61 patient evaluations for Duloxetine with a side effects rating of Severe

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Nov 20, 2016 (Started May 15, 2012)

  • Effectiveness
    None (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Severe (muscle and joint pain, muscle fatigue)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 180 mg Twice daily
Advice & Tips: This medication is habit forming and it’s withdrawal effects took nearly SEVEN MONTHS to wear off! Be careful when you are prescribed this medication..
Cost: < $25 monthly

  • 0 helpful marks

Oct 2, 2015 (Started Oct 01, 2010)

  • Effectiveness
    Can't tell (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Can't tell (for mild depression)
  • Effectiveness
    Can't tell (for generalized anxiety disorder)
  • Effectiveness
    Can't tell (for depressed mood)
  • Side effects
    Severe (decreased sex drive (libido))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Twice daily
Advice & Tips: I marked that there are negative and positive side effects with the Cymbalta. I will discuss the positive first. When I first started the Cymbalta the FDA had not yet approved it for helping fibro pain so I was just taking it to help control my mind that was bouncing all over the place, I could never settle my mind down and the Cymbalta helped with that along with sleeping medications. The negative side effect is still my lack of sex drive. It has gotten so bad that I don't even think about sex anymore. I feel so bad for my partner as he has gone nearly 2 years at one point without being intimate with me. Now my female parts are getting smaller and even trying to have sex causes me extreme pain on top of everything else. My doctor tried to get me to use some hormonal vaginal cream but it started me bleeding and I am 10 years past menopause so that was no good. I know that we should enjoy sex until the day we die and here I am not even 60 yet... I was horribly depressed by the death of my Mother-in-Law from May until September and I had to start taking Abilify again and now I am feeling a lot better. Cymbalta without Abilify doesn't seem to work very well for me.
Cost: < $25 monthly
Side effects: decreased sex drive (libido)

May 26, 2013 (Started Oct 01, 2010)

  • Effectiveness
    Can't tell (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Can't tell (for depressed mood)
  • Effectiveness
    Can't tell (for mild depression)
  • Effectiveness
    Can't tell (for generalized anxiety disorder)
  • Side effects
    Mild (decreased sex drive (libido))
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 90 mg Daily
Advice & Tips: When I saw my phychiatrist on May 23, 2013 he told me to divide my dose and take 30mg in the morning and 60mg with my night-time medicine. This is supposed to help my fatigue. I still have not felt any different. I am exhausted all the time and I do not think it is from the pain meds that I take. I was tired before I started taking those meds. I have lost my spark!
Cost: < $25 monthly
Side effects: decreased sex drive (libido)

Oct 1, 2010 (Started Oct 01, 2010)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (decreased sex drive (libido))
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 150 mg Daily
Advice & Tips: I think that Cymbalta has totally erased my sex drive. I do not experience drowsiness with Cymbalta. Drug companies have programs to help pay for the Cymbalta.
Cost: < $25 monthly
Side effects: decreased sex drive (libido)

Nov 29, 2009 (Started Oct 01, 2010)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: I take quite a high dose of the Cymbalta and I have to help it out with Abilify so I am not sure exactly how good the Cymbalta really is. It has been approved by the FDA to help with FM pain so it was a good choice that my doctor had made years before the FDA made the announcement. I still feel like I am on the edge of my seat alot of the time and I also take Visteril when needed.
Cost: < $25 monthly
Side effects: decreased sex drive (libido)

Apr 4, 2009 (Started Oct 01, 2010)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: It probably is working and I don't even know it.
Cost: < $25 monthly
Side effects: decreased sex drive (libido)

  • 0 helpful marks

Aug 29, 2015 (Started Jul 01, 2007)

  • Effectiveness
    Slight (for fibromyalgia)
  • Side effects
    Severe (fluid retention weight gain)
  • Adherence
    Never taken as prescribed
  • Burden
    Very hard to take
Dosage: 60 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Jun 18, 2015 (Started Apr 15, 2015)

  • Effectiveness
    Slight (for migraine)
  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    None (for generalized anxiety disorder)
  • Effectiveness
    Slight (for chronic pain)
  • Side effects
    Severe (restlessness (akathisia), uncontrollable crying, agitation, generalized anxiety disorder)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: Severely elevated anxiety levels to unmanageable levels
Cost: < $25 monthly

  • 0 helpful marks

Apr 5, 2014 (Started Jun 25, 2012)

  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    None (for depressed mood)
  • Side effects
    Severe (nightmares, heart palpitations, dizziness)
  • Adherence
    Always
  • Burden
    Not at all hard to take

Jul 1, 2013 (Started Jun 25, 2012)

  • Effectiveness
    None (for fibromyalgia)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Severe (nightmares, heart palpitations, dizziness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily

Jul 25, 2012 (Started Jun 25, 2012)

  • Effectiveness
    Slight (for fibromyalgia)
  • Side effects
    Mild (nightmares, heart palpitations, dizziness)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily

  • 0 helpful marks

Aug 24, 2013 (Started Feb 06, 2013)

  • Effectiveness
    None (for major depressive disorder)
  • Side effects
    Severe (brain fog)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 60 mg Daily
Cost: $100-199 monthly

  • 0 helpful marks

Mar 28, 2013 (Started Sep 13, 2012)

  • Effectiveness
    None (for mild depression)
  • Effectiveness
    None (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    None (for fibromyalgia)
  • Side effects
    Severe (anxious mood, tiredness, fuzzy thinking, grogginess, weepy)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 10 mg Daily
Advice & Tips: I felt Crappy before Cymbalta, and I feel evan worse from it! Now I not only have all the pain and uncomfortably symptoms, but my brain is also working so much slower! My choice to use Cymbalta was a Disparate attempt to regain evan a tiny bit of function and semblance of normalcy. It has been proving to be very LONG road to get back from the assault it had on my body, and it's almost ALL I can do to stay on the positive side of it. This was a BAD LESSON for me, and another GREAT Blow to my hope for healing! I suspect Seritonin Syndrome!

Nov 20, 2012 (Started Sep 13, 2012)

  • Effectiveness
    Moderate (for mild depression)
  • Effectiveness
    None (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    Moderate (anxious mood, tiredness, fuzzy thinking, grogginess, weepy)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 20 mg Daily
Advice & Tips: I was given a 60 mg cap which I open and muscle test. I get a Very clear amount every time, which seems to give me 3 days per capsule. =20mgs

  • 0 helpful marks

Mar 19, 2013 (Started Aug 15, 2012)

  • Effectiveness
    Moderate (for migraine headaches)
  • Effectiveness
    None (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    None (for major depressive disorder)
  • Effectiveness
    None (for fibromyalgia)
  • Side effects
    Severe (weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: I have been constantly hungry and binge-eating carbs and sugars which I have never done before! (I already ate too many carbs/sugars, didn't need this to be worse!)
Cost: < $25 monthly

  • 0 helpful marks

Jan 14, 2013 (Started Nov 04, 2012)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Severe (nausea, drowsy in morning, ejaculation dysfunction, cramps in legs, decreased sex drive (libido))
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 30 mg Daily
Advice & Tips: I started to reduce dosage to half, in order to stop in 10days. I prefer my moderate depression to any of the side effects Some side effects were severe, mainly the cramps I was startled by noting that I had serious malaise when I took Zaldiar (Tramadol) for pain in SOS Then I read safety warnings not to combine Cymbalta with Tramadol. I had chest pain and heart runs, for example

Nov 16, 2012 (Started Nov 04, 2012)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (nausea, drowsy in morning, decreased sex drive (libido))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily

  • 0 helpful marks

Nov 29, 2012 (Started Oct 22, 2012)

  • Effectiveness
    Slight (for fibromyalgia)
  • Side effects
    Severe (nausea, hallucinations, hot and cold flashes)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: The startup was a little rough but it has helped the mental side of it all for me. I only cried for 20 minutes after my first attack then got right back to work. Over time I'm thinking it might not always be this way but it was nice when it worked.
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
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