66 patient evaluations for Duloxetine with a side effects rating of Moderate

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Nov 16, 2017 (Started Mar 15, 2012)

  • Effectiveness
    Moderate (for pain)
  • Side effects
    Moderate (brain fog)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: < $25 monthly

Jun 20, 2016 (Started Mar 15, 2012)

  • Effectiveness
    Moderate (for pain)
  • Side effects
    Severe (brain fog)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: < $25 monthly

Dec 22, 2012 (Started Mar 15, 2012)

  • Effectiveness
    Slight (for pain)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Cost: < $25 monthly

Oct 22, 2012 (Started Mar 15, 2012)

  • Effectiveness
    Can't tell (for pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Nov 8, 2017 (Started Jul 15, 1996)

  • Effectiveness
    Slight (for persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Side effects
    Moderate (feelings of hopelessness)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Advice & Tips: It seems to work. I have been on it so long I cant remember not being on the medication
Cost: < $25 monthly
Side effects: feelings of hopelessness

  • 0 helpful marks

Jul 2, 2017 (Started Jan 18, 2017)

  • Effectiveness
    Slight (for pain)
  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Moderate (lack of motivation)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 60 mg Daily

  • 0 helpful marks

Jun 17, 2017 (Started Feb 23, 2017)

  • Effectiveness
    Slight (for major depressive disorder)
  • Side effects
    Moderate (dizziness, tremor(s))
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 30 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks

Mar 29, 2016 (Started Jul 01, 2015)

  • Effectiveness
    None (for fibromyalgia)
  • Effectiveness
    Can't tell (for bipolar II disorder)
  • Side effects
    Moderate (diabetic neuropathy)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Cost: < $25 monthly

  • 0 helpful marks

Sep 10, 2014 (Started Nov 26, 2012)

  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    Slight (for generalized anxiety disorder)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Feb 25, 2014 (Started Nov 06, 2006)

  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Major (for anxiety attacks)
  • Effectiveness
    Major (for anxiety attacks)
  • Side effects
    Moderate (excessive daytime sleepiness (somnolence), dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: Doctors tend to want you at the "recommended" dose, which is typically the highest. At the highest doses, the somnolence and dry mouth were unacceptable. I got the positive results at the lower titration doses without as much of the negative side effects. GPs don't know how hard it is to stop taking Cymbalta. I was trying to titrate down in order to start a different med. The doctor only gave me 15 days - 20 mg per day for a week, then 20 mg every other day for two weeks. I had severe dizziness, confusion, and irritability. The manufacturer no longer makes a 15 mg dose. I took my old 30 mg and opened them so I could take 10 mg a day. Took care of the dizziness almost immediately. FDA had a warning out about Cymbalta "Discontinuation Syndrome" back in 2009 (http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/PsychopharmacologicDrugsAdvisoryCommittee/UCM172866.pdf). When we're put on a medication, we're informed of the side effects, but not the side effects of withdrawing from said med. Cymbalta is hell to try to stop. Yes, it helps, but the side effects of stopping are worse than the symptoms that caused me to get on it in the first place. "All antidepressants have the potential to cause this after six weeks of use. However, no one has seen this type of severity until now. These newer antidepressant medications like Cymbalta are potent and have short half-lives. The primary reason people get sick when getting off these drugs is because they are left with too little serotonin. Without enough serotonin in the nervous system messaging system, everything goes haywire and the patient goes through hell. "Because many doctors and patients are unaware of these dangers, the diagnosis of Cymbalta Discontinuation Syndrome can be overlooked. Doctors need to get detailed medication histories and know that this syndrome can last for months. Once the diagnosis is made, then the doctor and the patient can try to treat the problem. In the above example, instead of restarting the Cymbalta, I elected to place the patient on an alternative antidepressant, Prozac. This medication replaces the Cymbalta and is easier to discontinue because it stays in the system longer (longer half-life)." You can find more info here: http://www.healthcentral.com/chronic-pain/c/27148/146506/cymbalta/

  • 0 helpful marks

Dec 10, 2013 (Started Mar 15, 2013)

  • Effectiveness
    None (for fibromyalgia)
  • Effectiveness
    None (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Side effects
    Moderate (weight gain)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 30 mg Daily
Advice & Tips: Weight gain when double dose only Didn't work at single dose 30 mg start dose changed to 60 mg quickly then to 120mg
Cost: $50-99 monthly

  • 0 helpful marks

May 26, 2013 (Started Nov 15, 2009)

  • Effectiveness
    Major (for fibromyalgia)
  • Effectiveness
    Moderate (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Side effects
    Moderate (chronic constipation, weight gain, tremor in hands)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: Potential unexpected benefits: improved incontinence Be VERY careful and take your time weening yourself off, after discussing with dr, of course! Cost kept increasing so I was considering going off of it. Finally, I was losing my insurance and I definitely could not afford to keep taking it! I thought it wasn't helping anymore but, after getting off of it, it appears it was helping after all, unless it is a coincidence that my health plummeted since!
Cost: $100-199 monthly

  • 1 helpful mark

Mar 15, 2013 (Started Jul 01, 2009)

  • Effectiveness
    None (for fibromyalgia)
  • Effectiveness
    None (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Side effects
    Moderate (feeling strange, bad dreams)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Cymbalta caused vivid horrible nightmares.
Cost: $25-49 monthly

  • 0 helpful marks
Last updated:
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