20 patient evaluations for Venlafaxine with a side effects rating of Moderate

351 members have decided to share their profiles only with other members of PatientsLikeMe.

Dec 15, 2017 (Started Jun 30, 2012)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Moderate (erectile dysfunction, difficulty with orgasm, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Twice daily

Oct 1, 2015 (Started Jun 30, 2012)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Mild (erectile dysfunction, difficulty with orgasm, nausea)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Twice daily

  • 0 helpful marks

Mar 21, 2017 (Started Sep 14, 2005)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Major (for major depressive disorder)
  • Effectiveness
    Major (for persistent depressive disorder (dysthymia))
  • Side effects
    Moderate (vivid nightmares)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 300 mg Daily
Advice & Tips: This was my 3rd try for a depression med. I have now been on in a majority of 18 years. It just works for me when I take it correctly. Don't suddenly stop, you must taper. It is really uncomfortable if you stop suddenly.
Cost: < $25 monthly

  • 1 helpful mark

Aug 15, 2013 (Started Jun 01, 2012)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (emotional lability, lack of motivation)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily
Advice & Tips: lack of emotion

  • 0 helpful marks

Aug 15, 2013 (Started Dec 30, 2012)

  • Effectiveness
    Slight (for depressed mood)
  • Effectiveness
    Slight (for social anxiety disorder)
  • Effectiveness
    Slight (for generalized anxiety disorder)
  • Side effects
    Moderate (night sweats, sweaty hands)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily

  • 0 helpful marks

Mar 1, 2013 (Started Jun 03, 2011)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Moderate (sexual dysfunction)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 150 mg Daily
Advice & Tips: Very difficult to withdraw from. Made me sexually promiscuous, a little known side effect.

  • 0 helpful marks

Feb 7, 2013 (Started Oct 04, 2009)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Can't tell (for persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for chronic idiopathic axonal polyneuropathy)
  • Side effects
    Moderate (vivid nightmares, sleepiness, somnolence, apathy, orthostatic hypotension, sexual dysfunction, tachycardia (fast heart rate))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 24.75 mg Daily
Advice & Tips: Effects both positive and adverse, both expected and unexpected, are pretty noticeable. Venlafaxine effects appear and fade much more rapidly than with SSRIs, and may change over time. By the time I stopped, I had been down to the lowest available dose of 25mg daily, which still seemed necessary for mood control, for a long time. It's been mostly helpful, and rarely burdensome except for the way it multiplies the effects of alcohol. Best unexpected benefit: mood control (less panicky/angry responses to cognitive dissonance). Intolerable imputed effect: Vividly unpleasant dreams, waking hyperventilating.
Cost: < $25 monthly
Side effects: excessive daytime sleepiness (somnolence), sleepiness, somnolence, orthostatic hypotension, sexual dysfunction, apathy, tachycardia (fast heart rate)

Mar 1, 2010 (Started Oct 04, 2009)

  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    Mild (sleepiness, somnolence, apathy, orthostatic hypotension, sexual dysfunction, tachycardia (fast heart rate))
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 37.5 mg Daily
Advice & Tips: Adverse effects now virtually disappear for me at 25 mg daily. This could change: some effects like the pounding in the ears at night or postural hypotension had previously disappeared at 37.5 mg; alarmingly rapid heart rate appeared over time at the same dosage (possibly associated with the transient hypotension). I'm still getting the good effects for the neuropathy, and the drug seems to act synergetically with cannabis in this area. The hypotension effect is probably aggravated by alcohol.
Cost: < $25 monthly
Side effects: excessive daytime sleepiness (somnolence), sleepiness, somnolence, orthostatic hypotension, sexual dysfunction, apathy, tachycardia (fast heart rate)

Nov 13, 2009 (Started Oct 04, 2009)

  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Can't tell (for anxious mood)
  • Side effects
    Mild (sleepiness, somnolence, apathy, orthostatic hypotension, sexual dysfunction)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 37.5 mg Daily
Advice & Tips: Venlaxafine seemed effective (within limits) for peripheral neuropathy and positive for relief of depression. Physical adverse effects at this dosage seemed minimal if any. Unresolved: Did this drug bliss me out too much, keeping me passive and lazy? And did it make me more suddenly irritable? I quit because of a pharmacy restriction (ironically based on the fact that I was taking "too little" of the drug), and will resume the trial once I talk to my primary provider in about 10 days.
Cost: < $25 monthly
Side effects: excessive daytime sleepiness (somnolence), sleepiness, somnolence, orthostatic hypotension, sexual dysfunction, apathy, tachycardia (fast heart rate)

Oct 28, 2009 (Started Oct 04, 2009)

  • Effectiveness
    Major (for anxious mood)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (sleepiness, somnolence, apathy, orthostatic hypotension, sexual dysfunction)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 37.5 mg Daily
Advice & Tips: Venlafaxine by itself seems both to increase my alertness and to bliss me out a little too much; I get lethargic at 75 mg daily. Even at 37.5 mg, I've added (after a bit of research) my previous low dose of bupropion (25 mg) back into the mix as a counterbalancing "upper". Although intermittent, I'm seeing some direct effects on the depression: e.g., posture as well as mood.
Cost: < $25 monthly
Side effects: excessive daytime sleepiness (somnolence), sleepiness, somnolence, orthostatic hypotension, sexual dysfunction, apathy, tachycardia (fast heart rate)

  • 0 helpful marks

Jun 24, 2011 (Started May 25, 2011)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily
Advice & Tips: I had increased fatigue with this drug. After telling my neurologist about it, he suggested changing to Cymbalta. I'll give that a try.
Cost: < $25 monthly

  • 0 helpful marks

Jun 2, 2010 (Started Mar 15, 2010)

  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Moderate (excessive daytime sleepiness (somnolence))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 225 mg Daily
Advice & Tips: Dr. had me stop this and go to the 150mg XR capsuel
Cost: < $25 monthly
Side effects: excessive daytime sleepiness (somnolence)

  • 0 helpful marks

Apr 29, 2010 (Started Apr 19, 2010)

  • Effectiveness
    Slight (for bipolar disorder)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    Moderate (sexual dysfunction, blurry vision, dry mouth, loss of energy, tired eyes)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: $25-49 monthly
Side effects: tired, nonchalant attitude., dry mouth, loss of energy, sexual dysfunction, tired eyes, blurry vision

  • 0 helpful marks

Feb 22, 2010 (Started Feb 15, 2010)

  • Effectiveness
    Major (for depressed mood)
  • Side effects
    Moderate (nausea)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 75 mg Daily
Side effects: nausea

  • 0 helpful marks
Last updated:
Showing 10 of 20 patient evaluations for Venlafaxine