37 patient evaluations for Duloxetine taken for the purpose of 'depressed mood' with a perceived effectiveness rating of Moderate

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Nov 20, 2016 (Started May 15, 2012)

  • Effectiveness
    None (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Severe (muscle and joint pain, muscle fatigue)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 180 mg Twice daily
Advice & Tips: This medication is habit forming and it’s withdrawal effects took nearly SEVEN MONTHS to wear off! Be careful when you are prescribed this medication..
Cost: < $25 monthly

  • 0 helpful marks

May 29, 2016 (Started Jul 15, 2002)

  • Effectiveness
    Can't tell (for myalgic encephalomyelitis/chronic fatigue syndrome)
  • Effectiveness
    Can't tell (for fibromyalgia)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily

Mar 1, 2011 (Started Jul 15, 2002)

  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Slight (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Advice & Tips: For depression (which occured years before FMS or CFS), it took me several different depression meds to find out one that helped or didn't cause undesirably side effects. Cymbalta works for me. Don't give up if the firstbtwo or three don't work.

  • 1 helpful mark

May 24, 2014 (Started May 24, 2014)

  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Slight (for pain)
  • Side effects
    Mild (dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 120 mg Daily
Advice & Tips: Not only does it help for depression it helps for pain control.
Cost: < $25 monthly

  • 0 helpful marks

Feb 25, 2014 (Started Nov 06, 2006)

  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Major (for anxiety attacks)
  • Effectiveness
    Major (for anxiety attacks)
  • Side effects
    Moderate (excessive daytime sleepiness (somnolence), dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: Doctors tend to want you at the "recommended" dose, which is typically the highest. At the highest doses, the somnolence and dry mouth were unacceptable. I got the positive results at the lower titration doses without as much of the negative side effects. GPs don't know how hard it is to stop taking Cymbalta. I was trying to titrate down in order to start a different med. The doctor only gave me 15 days - 20 mg per day for a week, then 20 mg every other day for two weeks. I had severe dizziness, confusion, and irritability. The manufacturer no longer makes a 15 mg dose. I took my old 30 mg and opened them so I could take 10 mg a day. Took care of the dizziness almost immediately. FDA had a warning out about Cymbalta "Discontinuation Syndrome" back in 2009 (http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/PsychopharmacologicDrugsAdvisoryCommittee/UCM172866.pdf). When we're put on a medication, we're informed of the side effects, but not the side effects of withdrawing from said med. Cymbalta is hell to try to stop. Yes, it helps, but the side effects of stopping are worse than the symptoms that caused me to get on it in the first place. "All antidepressants have the potential to cause this after six weeks of use. However, no one has seen this type of severity until now. These newer antidepressant medications like Cymbalta are potent and have short half-lives. The primary reason people get sick when getting off these drugs is because they are left with too little serotonin. Without enough serotonin in the nervous system messaging system, everything goes haywire and the patient goes through hell. "Because many doctors and patients are unaware of these dangers, the diagnosis of Cymbalta Discontinuation Syndrome can be overlooked. Doctors need to get detailed medication histories and know that this syndrome can last for months. Once the diagnosis is made, then the doctor and the patient can try to treat the problem. In the above example, instead of restarting the Cymbalta, I elected to place the patient on an alternative antidepressant, Prozac. This medication replaces the Cymbalta and is easier to discontinue because it stays in the system longer (longer half-life)." You can find more info here: http://www.healthcentral.com/chronic-pain/c/27148/146506/cymbalta/

  • 0 helpful marks

Mar 15, 2013 (Started Sep 10, 2006)

  • Effectiveness
    Moderate (for burning sensation)
  • Effectiveness
    Moderate (for nerve pain (neuralgia))
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (constipation, weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: $100-199 monthly

  • 0 helpful marks

Jan 14, 2013 (Started Nov 04, 2012)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Severe (nausea, drowsy in a.m., ejaculation dysfunction, cramps in legs, decreased sex drive (libido))
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 30 mg Daily
Advice & Tips: I started to reduce dosage to half, in order to stop in 10days. I prefer my moderate depression to any of the side effects Some side effects were severe, mainly the cramps I was startled by noting that I had serious malaise when I took Zaldiar (Tramadol) for pain in SOS Then I read safety warnings not to combine Cymbalta with Tramadol. I had chest pain and heart runs, for example

Nov 16, 2012 (Started Nov 04, 2012)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (nausea, drowsy in a.m., decreased sex drive (libido))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily

  • 0 helpful marks

Dec 30, 2012 (Started Sep 15, 2012)

  • Effectiveness
    Slight (for social anxiety disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    None (for generalized anxiety disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: $50-99 monthly

  • 0 helpful marks

Sep 12, 2012 (Started Oct 15, 2009)

  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Mild (weight gain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Aug 16, 2012 (Started May 15, 2012)

  • Effectiveness
    Moderate (for social anxiety disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Slight (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Advice & Tips: it was difficult for me to access whether medicine was working or not, due to the rest of the medicines i have been switched on and off

  • 0 helpful marks

Jul 22, 2012 (Started Jul 01, 2011)

  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 60 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 10 of 37 patient evaluations for Duloxetine