9 patient evaluations for Milnacipran taken for the purpose of 'fibromyalgia' with a perceived effectiveness rating of Major

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Jun 15, 2015 (Started Jul 01, 2010)

  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    Mild (weight gain)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 12.5 mg Daily
Advice & Tips: I felt that Savella was very effective in managing FM symptoms, however, with Obamacare, it was too expensive to keep taking it. I gradually weened off the medication, and am now using supplements from Melaleuca and JuicePlus and am doing just as well.
Cost: $200+ monthly

  • 1 helpful mark

Jul 27, 2012 (Started Jun 30, 2012)

  • Effectiveness
    Major (for pain)
  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    Severe (atrial fibrillation, tachycardia (fast heart rate), heart stopped, heart palpitations)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Twice daily
Advice & Tips: Although Savella almost killed me... It did work 99% of my symptoms were gone. I felt like I had a new lease on life. On day 11 I felt weird like my heart was pounding for no reason non-stop
Cost: < $25 monthly

  • 0 helpful marks

May 9, 2011 (Started Apr 23, 2011)

  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    Moderate (irritability)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 50 mg Daily
Cost: $100-199 monthly
Side effects: irritability

  • 0 helpful marks

Jan 13, 2011 (Started Dec 10, 2010)

  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    Moderate (nausea, racing heart feeling, brain fog, restless feeling in legs, giddiness, jittery feeling)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 100 mg Daily
Advice & Tips: I was joking with my partner yesterday that "Save-ella" is aptly named :) I've been on it for almost a month now and just refilled for the next three months at my new stable dosage (100mg/day). I requested, and got, a rx for one 100mg tab a day instead of two 50mg tabs because it would be half the cost through my insurance that way. I noticed a HUGE difference with Savella. Clearly whatever that's wrong with me Savella fixes. I do notice the odd nausea or "hot flash" from time to time, but it's gone down in intensity and frequency considerably. And, frankly, the side effects are worth the benefits for me. Actually -- and this could be because it's winter -- I've felt colder in general than I did when I was taking tramadol daily, which also made me sweat. The only problem that I'm still struggling with is an amplification of RLS symptoms, which is common with anything that increases serotonin. I feel almost normal again. I haven't felt like this in four years or so. For people considering taking Savella, two recommendations are to advance dosage MUCH slower than the mfgr suggests. I didn't up my dose until I was OK at the dose I was already at. Also, take it with food. This forced me to eat breakfast every day, which I never did before. Savella is not a 100% cure. I'd say it's muted my pain by about 40-50%, which is a huge improvement. It's given me the "space" to actually consider exercising, which is also supposed to help FM.
Cost: $25-49 monthly
Side effects: jittery feeling, racing heart feeling, giddiness, restless feeling in legs, excessive sweating, brain fog, nausea

Dec 24, 2010 (Started Dec 10, 2010)

  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    Moderate (nausea, racing heart feeling, brain fog, restless feeling in legs, jittery feeling)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Now that I've finally stabilized my Savella dosage, I have to say that's I'm extremely pleased with this drug. I feel like myself again for the first time in five years. The strongest positive effect has been with my energy level. I don't have to drag myself to and from bed anymore. I don't dread going up the stairs to fetch something. I actually can do something after work at night instead of collapse in my recliner. I'm still tired at the end of the day, but it's a normal, ready-to-go-to-bed tired instead of exhaustion. I'd say it's muted my pain level by about 40-50%, which feels wonderful. I'm still managing what's left through other medications, but having the fatigue lifted makes a big difference in my mood. If I have to rest because of physical pain I can still be mentally active, which I wasn't able to do before because of brain fog. Lots of people complain about side effects with Savella. As long as I eat a few bites of something in the morning I have no nausea. I'm not sweating anymore either, which is nice, because I was sweating constantly on the tramadol. I think if you want to give this drug a try, make the commitment to go up SLOWLY on your dose, and give it a little time before you expect to see anything. I didn't advance my dose until I was fully adjusted to the dose I was already on, so it was fairly painless.
Cost: $25-49 monthly
Side effects: jittery feeling, racing heart feeling, giddiness, restless feeling in legs, excessive sweating, brain fog, nausea

Dec 20, 2010 (Started Dec 10, 2010)

  • Effectiveness
    Moderate (for fibromyalgia)
  • Side effects
    Moderate (nausea, racing heart feeling, brain fog, restless feeling in legs, jittery feeling)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 75 mg Daily
Advice & Tips: Yesterday and today were the first days I really started to feel better. Last week I noticed I was feeling more cheerful overall, but it wasn't until I hit the 75mg/day mark that it started to make an impact on my pain. I stepped up pretty gradually -- each time I had a little bit of nausea (unless I forgot to eat when I took it, and then I had a LOT of nausea). I feel a LOT more energetic, almost a nervous, over-caffeinated energy which is a little annoying. I expect that to go away after awhile. I take my afternoon dose about 3/4pm so it doesn't interfere with my sleep. Last week I was having a terrible time with RLS symptoms, which might have been because I was coming off of tramadol which is often used for RLS. Last couple of nights were better but I stayed awake until I was exhausted and then took a double does of melatonin when I finally did go to bed. So far feeling REALLY positive about this drug. I feel like "myself" for the first time in years. I hope it continues!
Cost: $25-49 monthly
Side effects: jittery feeling, racing heart feeling, giddiness, restless feeling in legs, excessive sweating, brain fog, nausea

Dec 15, 2010 (Started Dec 10, 2010)

  • Effectiveness
    Can't tell (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg Daily
Advice & Tips: On day 5 of my titration for Savella. Doc was worried about nausea so he started me on 12.5mg a day. When I took the rx to the pharamcy I found out I could get 25mg tablets instead and split them for a cost savings. My insurance copay was $10 for 15 tablets instead of $17.75 for 30 12.5mgs, which the pharmacy didn't stock. Note: 25mg tablets are frickin' tiny! Anyway, I did the 12.5mg a day, with my bedtime medicine cocktail, for 4 days. No effects, bad or good. Started 2 x 12.5mg at lunch and bedtime yesterday and today. If nothing happens, I will go to 2 x 25mg tomorrow. Because of the possible serotonin interaction with Savella, I have to discontinue my tramadol, which I've been on for over a year. I've halved my dose and plan to be done by Friday. I feel like crap, so clearly the tramadol has been doing something for me.
Side effects: jittery feeling, racing heart feeling, giddiness, restless feeling in legs, excessive sweating, brain fog, nausea

  • 2 helpful marks

Oct 5, 2010 (Started Oct 05, 2010)

  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg Daily
Cost: $25-49 monthly

  • 0 helpful marks

May 14, 2010 (Started May 14, 2010)

  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    Severe (excessive sweating, difficulty urinating (dysuria))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Very difficult to reach recommended dosage. Lots of side effects but little by little was able to make it. Lot's of sweating, issues with urination, hypoglycemia feeling, and restlessness at night. Appetite is greatly affected. That isn't so much of a problem.
Cost: < $25 monthly
Side effects: difficulty urinating (dysuria), excessive sweating

  • 0 helpful marks

Feb 18, 2010 (Started Oct 01, 2009)

  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    Mild (constipation)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: The Savella causes constipation. I manage it may eating more fiber and drinking lots of water.
Cost: $25-49 monthly
Side effects: constipation

  • 0 helpful marks

Feb 1, 2010 (Started Oct 05, 2009)

  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    Mild (fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: It was amazing stuff. I am now taking a light anti-depressant but it is not as effective as the Savella. My Husband's company went for the cheap and changed insurance to a very slight care provider so now that wasn't covered although the doctors wrote to them they completely turned it all down. The new stuff is better than nothing but not much. Savella was a miracle if you can get it covered you owe yourself a trial. I am in so much better shape all except the back went out already and I was down with pain for a few days. With Savella I have a more positive outlook, better sleep, rested sleep. Now my sleep patterns are starting to turn and I am not doing as well. But I am trying to make it work. Savella again was a miracle for me. :) It was 33.00 for month with insurance.
Cost: $100-199 monthly
Side effects: fatigue

Dec 29, 2009 (Started Oct 05, 2009)

  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    Mild (fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Someone on here said they took Savella and had stomach problems after taking. They suggested to eat half of your food for say breakfast take your pill then eat the rest. I do that still but sometimes I am unable and seem to tolerate it quite well. I am a different person. I thought I was going to have to go on disability but I feel so much more positive. I really felt so tired and lacking any energy. I was working 6 hours per day. Starting the 4th of Jan 2010 I will go back to 40 hours. They agreed I could come in at 9 am and stay until 5 pm which is really 7.5 hours. After a week I hope I will still feel better. But it may be difficult for me to work that long. Only time will tell. But I have to say Savella is a miracle. I really thought here we go turn 60 and put me out to pasture. I so hope this keeps on working. I wish everyone would try it and see if it works. I still have pain, the doctor prescribed Naproxyn which is helping. I can handle the pain to a degree just not the fatigue. I feel like Eyore when I get fatigued. I hope this helps even one person.
Cost: $25-49 monthly
Side effects: fatigue

  • 3 helpful marks

Nov 19, 2009 (Started Oct 28, 2009)

  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    Mild (fatigue, excessive sweating)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: 1. Easy to manage; side effects are mild, at least in comparison to previous medications, such as Cymbalta and Lyrica. Those medications, along with others, had moderate to severe side effects, at least for me. 2. Unexpected benefits: Have tried virtually everything for fibromyalgia, so I had sort of lost hope. So it has been extraordinarily positive to find that Savella really works well. 3. Impact on daily life includes the ability to function during the day, which has been a long-time schedule for me. I would often stay up all night and sleep all day, which made a variety of things extremely difficult.
Cost: $25-49 monthly
Side effects: fatigue, excessive sweating

  • 13 helpful marks
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Showing 9 of 9 patient evaluations for Milnacipran