19 patient evaluations for Rituximab

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May 25, 2010 (Started May 22, 2008)

  • Effectiveness
    Major (for neuromyelitis optica)
  • Side effects
    Severe (allergic reaction)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 10000 mg Every 3 months
Advice & Tips: Make sure you are not allergic to the medication. Thought it was just an chronic infusion rxn, when I consulted the allergist, he said I was very allergic to it. Hated to stop the medication as it was very helpful. If you are allergic to guninea pigs/ mice do not take it!
Cost: $200+ monthly
Side effects: allergic reaction

Mar 7, 2010 (Started May 22, 2008)

  • Effectiveness
    Major (for neuromyelitis optica)
  • Side effects
    Moderate (allergic reaction)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 10000 mg Every 3 months
Cost: $100-199 monthly
Side effects: allergic reaction

Mar 5, 2010 (Started May 22, 2008)

  • Effectiveness
    Can’t tell (for neuromyelitis optica)
  • Side effects
    Moderate (allergic reaction)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 1000 mg Every 3 months
Advice & Tips: Due to increased severity of pain from the Devic's uncontrolled with the max dose of 200mcg Fentanyl, it was decided that by neurology to do an early dose of Rituxan. In other words, instead of 3 months, we did the Rituxan in 2 months as in the past this has helped with the pain. The infusion was over 24 hours and I had severe issues with hypotension and ventricular arrythmias, needed increased fluid support and keeps the support meds scheduled at every 6 hours (increased the dosages of Benadryl and demerol, tylenol). Will see if the pain improves!
Cost: $100-199 monthly
Side effects: allergic reaction

Feb 28, 2010 (Started May 22, 2008)

  • Effectiveness
    Major (for neuromyelitis optica)
  • Side effects
    Severe (allergic reaction)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 1000 mg Every 3 months
Advice & Tips: This is the only tx that seems to be best though for some reason my relapses try to recur with two months after the infusion. With the other chemo (MTX) I had too many life threatening infections so I had to stop, I will have to deal with the side effects for now. I do feel great for the first two months after the treatment. Usually the tx is done outpatient, but in my case I must stay inpt and the infusion is done between 12-18 hours due to side effects. Need hydration and cardiac monitoring before, during amd after to help deal/ monitor some of the adverse side effects. Myneurologist doesn't understand these increasing adverse reactions with each successive dose. Afraid to increase the frequency for this reason.
Cost: $100-199 monthly
Side effects: allergic reaction

  • 2 helpful marks

Oct 30, 2009 (Started Feb 01, 2009)

  • Effectiveness
    Major (for neuromyelitis optica)
  • Side effects
    Mild (insomnia)
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 10 mg Every Other Week
Advice & Tips: Has made me feel alot better; however, I still have symptoms from permanet scare tissue damage. However; after my last two treatments: 1) Feb 2) Oct...both MRI's following each treatment showed significant improvement and no activity and no inflamation. I was and am happy with the results. However, if you are thinking about starting this treatment, it is very important to monitor your B cells through monthly Blood Tests to make sure the medication is doing its job and working.
Side effects: insomnia

  • 1 helpful mark

Dec 31, 2008 (Started May 05, 2005)

  • Effectiveness
    Slight (for Other)
  • Side effects
    Mild (low blood pressure)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 1000 other Yearly
Advice & Tips: In 2005 when I had this treatment it gave me moderate improvement but this time in 2008 I only had slight improvement and that only seemed to last for not quite a full year, unlike the other time which I had some benefit up to 3 years.
Cost: $200+ monthly
Side effects: low blood pressure

  • 1 helpful mark

Mar 1, 2010 (Started Nov 12, 2009)

  • Effectiveness
    Can’t tell (for multiple sclerosis)
  • Side effects
    Moderate (respiratory infections)
  • Adherence
    Never taken as prescribed
  • Burden
    Somewhat hard to take
Dosage: 10 mg Weekly
Side effects: respiratory infections

Dec 9, 2009 (Started Nov 12, 2009)

  • Effectiveness
    Can’t tell (for multiple sclerosis)
  • Side effects
    Moderate (respiratory infections)
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: 10 mg Weekly
Advice & Tips: Got too many respiratory infections after the first dose. Second dose, tomorrow after three weeks
Side effects: respiratory infections

  • 1 helpful mark

Mar 25, 2013 (Started Mar 15, 2006)

  • Effectiveness
    Major (for systemic lupus erythematosus)
  • Effectiveness
    Major (for rheumatoid arthritis)
  • Side effects
    Moderate (nausea, migraine)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: As needed
Advice & Tips: I use the Scopalamine Patch the night before (helps eliminate the nausea - I have tried Phenergan and Zofran -both used to work, but don't any more). Occasionally I have side effects during the drip (itchiness in throat, ears and head - now they add tagamet and claritin to stop that - last infusion it worked well). Retuxan has changed my life - I was unable to work before i was on it- after the first infusion about 1 month later I went to EUROPE for a week (I never could have gone before!) and I walked, went to Paris, London, had a blast! Prior to retuxan I had stopped working completely and spend most of my life in bed. I had researched this drug and was waiting for for the FDA to approve. As soon as it did my doc got approval ( had been on EVERYTHING prior to that) and had a needle in my arm! I was the second patient to receive treatment at my clinic! It is a godsend! I'm not "normal" but I am a LOT better (I can tell when I can't afford it- it is pricey but the company has started a program to help you pay for what insurance wont (it's apprx 7-20,000 per infusion)So with a copay or if you get it early in the year you owe all of your out of pocked and deductible (3K for me!). It is an all day infusion (about 6 hours) and bc of problems years ago with an insurance company that paid for it, then when we moved to a different insurance company they went back and "retroactively denied treatment" I fought but still owed the clinic $8000 which I did NOT have on hand. They have told me I can NEVER get infused at their clinic (which is a problem bc many clinics are with hospitals and they won't let me get infusioned if my doc doesn't have privs, or the hospitals want the doctor to get approval and her office refuses since they aren't getting paid. SO..advice - even if your doctor says you are approved CALL INSURANCE find out how much you will owe. Once it's in your arm you could owe a lot of money. AND some clinics don't actually get authorization (then they will charge you a LARGE fee - your insurance). BUT apart from the cost (LOL) it is brilliant! OH - the typical dose is 2 infusions 2 weeks apart every 4 months (that is NOT ON THE LIST OF CHOICES). You can get it more frequently (and I did once) but you need to get approval from your insurance.

  • 1 helpful mark

Sep 15, 2014 (Started Jul 15, 2012)

  • Effectiveness
    Slight (for rheumatoid arthritis)
  • Side effects
    Mild (sinus headaches)
  • Adherence
    Always
  • Burden
    Very hard to take
Dosage: 10 mg Every 3 months
Advice & Tips: This was an infusion. Go prepared to sit back and relax. Take the Benedryl offered to you and go to sleep for a while. Depending on the dose, you may be there for five hours (or as little as two). Bring a book. No work. No annoying phone calls. This was a perfect excuse to rest. You will havwe to go into the doctor's office and miss a day of work. Immediately after an infusion I would be hungry and tired. So I would go home and take a nap after lunch. Because of small veins and constant dehydration, it would take five to five and a half hours for me to get my dosage. I went once every six months initially, then once every four months. If after three doses you were not getting any relief, talk to your doctor. She may wish to change the number of times you were getting treated.

  • 1 helpful mark

Jan 9, 2009 (Started Aug 29, 2008)

  • Effectiveness
    Moderate (for Other)
  • Side effects
    Mild (migraine headaches)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 10 mg Yearly
Cost: $100-199 monthly
Side effects: migraine headaches

Oct 10, 2008 (Started Aug 29, 2008)

  • Effectiveness
    Can’t tell (for Other)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 10 mg Yearly
Cost: < $25 monthly
Side effects: migraine headaches

  • 0 helpful marks

Jan 21, 2009 (Started Dec 10, 2007)

  • Effectiveness
    Major (for neuromyelitis optica)
  • Side effects
    Mild (tiredness, muscle pain)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: As needed
Cost: $200+ monthly
Side effects: muscle pain, tiredness, tiredness

  • 0 helpful marks

Nov 1, 2009 (Started May 01, 2008)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 500 mg Every 3 months
Cost: < $25 monthly

Jun 18, 2009 (Started May 01, 2008)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Cost: < $25 monthly

  • 0 helpful marks

Jul 24, 2008 (Started May 29, 2008)

  • Effectiveness
    Slight (for Prevention of recurrence of disease)
  • Side effects
    Moderate
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 1 other Weekly
Advice & Tips: It's a painless infusion. You don't feel, taste, or smell anything.
Cost: $50-99 monthly
Side effects: hair loss, hair thinning, nausea, hair curling, fatigue, fatigue

  • 0 helpful marks
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Showing 10 of 19 patient evaluations for Rituximab