133 patient evaluations for Carbidopa-Levodopa

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Jan 12, 2017 (Started Jun 30, 2004)

  • Effectiveness
    Major (for restless legs syndrome)
  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (headaches, headache)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: I am so afraid of increasing my dose of carbidopa/levadopa that I still have not even tried it. I might be able to move better if I increased it but I fear the nausea, the dyskinesia, the near syncope. However, I have such back pain that it interferes with everythingI want to do. I can only walk for a short time before I am looking for a place to sit. That eliminates any tours, any walks in the woods. I used to enjoy walking. And I have gained a lot of weight from being sedentary.
Cost: < $25 monthly

Apr 24, 2016 (Started Jun 30, 2004)

  • Effectiveness
    Can't tell (for restless legs syndrome)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (headaches, headache)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: The carbidopa/levodopa works the best for me to lessen the symptoms of PD. Other Rx drugs I tried didn't work as well or they worked well for symptoms but caused syncope or near syncope and left me feeling drained. It took many months to find the right med & the right dose. I do realize that carb/levo may cause tardive dyskinesia before it's over. But right now it is the best I can do & I want to enjoy it while I can. I can do quite a bit still . I owe that to the carb/levo.
Cost: < $25 monthly

Nov 26, 2015 (Started Jun 30, 2004)

  • Effectiveness
    Moderate (for restless legs syndrome)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (headaches, headache)
  • Adherence
    Usually
  • Burden
    Very hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: My niece showed me how to set my iPhone clock to have a timer go off every day at 1pm to remind me to take my mid day dose of carb/levo & pramipexole. It works!!! It has worked. I have not missed a day since using the timer. I now am aware of "wearing off" of the meds. I never noticed it until a few months ago. At my last appt with Neurologist he increased my carb/levo to 1 1/2 TID. He said to increase gradually. I haven't increased just yet because I want to be firmly on the previous dose first which I am with this timer helping me. Soon I will try the new increase.
Cost: < $25 monthly

Jun 5, 2015 (Started Jun 30, 2004)

  • Effectiveness
    Can't tell (for restless legs syndrome)
  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (headaches, headache)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: Now I am taking a new dose-1 TID-gradually titrating up from 1/2 TID. I still miss my noon dose although not as often. It is difficult remembering. I do notice the increase in dose is helping me stand up straighter longer & within about an hour of taking my dose. It is a pain in the neck to take 3 x a day but it improves my symptoms.
Cost: < $25 monthly

Feb 11, 2015 (Started Jun 30, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Major (for restless legs syndrome)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: I no longer am seeing any improvement. Maybe I have just gotten used to it & no longer notice it. Maybe it is time to increase again.
Cost: < $25 monthly

Nov 10, 2014 (Started Jun 30, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: This formula (immediate release) was given so I can see if I can get more carb/levo into me for better symptom control, but the problem with this formula is that I have a hard time remembering the noon dose. I am having an easier time remembering it now that I am retired, but I still forget sometimes. So far I MAY have experienced improvement in symptoms: I occasionally get relief from my back pain. I think the pain is caused by the postural changes with PD & anything I do to correct posture relieves the pain. This 1/2 pill taken 3x a day gives me more levo than I was getting with the CR 50/200 1/2 daily. Just that small amt more seems to have helped me stand up better which relieves the pain.
Cost: < $25 monthly

  • 0 helpful marks

Jan 3, 2017 (Started Jun 23, 2006)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (jerky movements)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 6 mg Daily
Cost: $100-199 monthly

  • 0 helpful marks

Jan 3, 2017 (Started Mar 01, 2012)

  • Effectiveness
    Moderate (for tremor in hands)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (heartburn, nausea during and after eating)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 x 25-100 mg Daily
Advice & Tips: when I first started this treatment the doctor prescribed Levadopa 25mg to balance out the nausea . It really seem to work well . I've since been taken off the additional Levadopa since my insurance will not cover it . If your insurance will cover it then I would advise asking about the Levadopa 25mg to go with the carbadopa/levadopa 100/25mg if you have nausea .
Cost: $50-99 monthly

  • 0 helpful marks

Nov 10, 2016 (Started Jan 20, 2009)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (jerky movements)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25-250 mg Five times daily
Cost: $25-49 monthly

May 26, 2015 (Started Jan 20, 2009)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Moderate (jerky movements)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 4 x 25 mg-250 mg Daily
Cost: < $25 monthly

May 19, 2013 (Started Jan 20, 2009)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (jerky movements)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 4 x 25 mg-100 mg Daily
Advice & Tips: I use a talking alarm watch to help me take my medication on time.
Cost: < $25 monthly

May 24, 2009 (Started Jan 20, 2009)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 x 25 mg-100 mg Daily
Advice & Tips: Take your pills on time
Cost: $25-49 monthly

  • 0 helpful marks

Oct 11, 2016 (Started Jun 30, 2012)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (freezing of gait)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 25-100 mg Twice daily
Advice & Tips: n/a
Cost: < $25 monthly

  • 0 helpful marks

Sep 23, 2016 (Started Jul 27, 2011)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (jerky movements)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Advice & Tips: Have stopped this and have been on Rytary since about August 2015
Cost: < $25 monthly
Side effects: jerky movements

Oct 15, 2015 (Started Jul 27, 2011)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (jerky movements)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Rytary is better. It gives me a much smoother delivery.
Cost: < $25 monthly
Side effects: jerky movements

Feb 1, 2015 (Started Jul 27, 2011)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (jerky movements)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: As needed
Advice & Tips: On the average, it is best to take 0.75 tablet every 4.00 to 4.25 hrs. If I am doing something physical like a long walk or if I have to keep moving my whole body for 2-3 hours, then 1.00 tablet. Do not do this if sitting at a desk-dyskinesia.
Cost: < $25 monthly
Side effects: jerky movements

Nov 8, 2014 (Started Jul 27, 2011)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (jerky movements)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: As needed
Advice & Tips: It's the fall/winter season, and I made a med change. IT coincides with the daylight getting shorter. About mid-to late Sept I increase the Cymbalta(depression) from 60mg to 120mg. This seems to affect how the L-dopa is metabolized. For a few weeks I was taking 1 whole tablet (100/25), every 5-6 hrs. The 0.75 dose wasn't doing its work. I also start on modafinil for alertness. Due to Rx screw up I wasn't able to start in Oct, but had to start in Nov. I was maintaining, but now I feel better with the modafinil. Like someone turning up the TV brightness switch just a little bit. But now I think I am very sensitive to the amount of L-dopa. I will work it out.
Cost: < $25 monthly
Side effects: jerky movements

Apr 18, 2013 (Started Jul 27, 2011)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (jerky movements)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: As needed
Advice & Tips: This survey doesn't account for the way i take L-dopa. I started out at 1 tablet every 6 hours. Now I am at 0.75 tablet every 4 hours. So this means i am taking a smaller dose at more frequent intervals as Parkinson's progresses. If I take more than needed, the dyskinesia starts. If I go too long without a dose (usually sitting at work or computer), forget to take it, hand tremor starts.
Cost: < $25 monthly
Side effects: jerky movements

  • 0 helpful marks

Jun 11, 2016 (Started Sep 15, 2010)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Moderate (muscle and joint pain, nausea and vomiting)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 12 x 25-100 mg Five times daily
Advice & Tips: During a month long stay in hospital I did not have a problem with the nausea and vomiting.
Cost: $25-49 monthly

Jun 30, 2013 (Started Sep 15, 2010)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (nausea and vomiting)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 4 x 25 mg-100 mg Daily
Advice & Tips: In spite of the recommendation of taking the pills an hour before eating, I take it with food.
Cost: $25-49 monthly

  • 0 helpful marks

May 30, 2016 (Started Aug 26, 2008)

  • Effectiveness
    Major (for tremor(s))
  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Moderate (jerky movements, on to off fluctuations worsening, balance problems, dizziness, nausea, sleep problems, fatigue)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 3 x 25-100 mg Five times daily
Cost: < $25 monthly
Side effects: dizziness, sleep problems, nausea, fatigue

Jan 9, 2014 (Started Aug 26, 2008)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Major (for tremor(s))
  • Side effects
    Moderate (dizziness, nausea, sleep problems, fatigue)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 10 x 25 mg-100 mg Daily
Advice & Tips: This medication appears to be the primary building block with individuals having the type that I have (Mainly tremors and speech). It all too often happens that you feel so good that you fail to realize that it is time for another dose. Stress is a big factor in the degree of symptoms experienced. In stressful situations I sometimes take an addition pill. This seems to help.
Cost: < $25 monthly
Side effects: dizziness, sleep problems, nausea, fatigue

Mar 25, 2013 (Started Aug 26, 2008)

  • Effectiveness
    Major (for tremor(s))
  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (dizziness, nausea, sleep problems, fatigue)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 x 25 mg-100 mg Daily
Cost: < $25 monthly
Side effects: dizziness, sleep problems, nausea, fatigue

Feb 13, 2012 (Started Aug 26, 2008)

  • Effectiveness
    Major (for tremor(s))
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (dizziness, nausea, sleep problems, fatigue)
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 10 x 25 mg-100 mg Daily
Cost: < $25 monthly
Side effects: dizziness, sleep problems, nausea, fatigue

Jan 27, 2009 (Started Aug 26, 2008)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Major (for tremor(s))
  • Side effects
    Moderate (dizziness, nausea, sleep problems, fatigue)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 2 x 25 mg-100 mg Daily
Cost: < $25 monthly
Side effects: dizziness, sleep problems, nausea, fatigue

Dec 1, 2008 (Started Aug 26, 2008)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Effectiveness
    Slight (for tremor(s))
  • Side effects
    Mild (nausea, sleep problems)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 2 x 25 mg-100 mg Daily
Advice & Tips: uncertain at this point
Cost: < $25 monthly
Side effects: dizziness, sleep problems, nausea, fatigue

  • 0 helpful marks

Apr 24, 2016 (Started Jun 30, 2012)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (involuntary movement)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: I look and feel better taking the meds.  My hand writing is much better.  I don't stare as much.  I move better.
Cost: < $25 monthly

  • 0 helpful marks

Mar 23, 2016 (Started Jul 16, 2014)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
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