• Effectiveness

  Can't tell (for chronic inflammatory demyelinating polyneuropathy)
• Side effects

  None (for Overall)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 5 mg Weekly

Cost: < $25 monthly

• Effectiveness

  Moderate (for rheumatoid arthritis)
• Side effects

  Moderate (for Overall) (cognitive impairment)
• Adherence

  Usually
• Burden

  Somewhat hard to take

Dosage: 0.8 mL Weekly

Cost: < $25 monthly

• Effectiveness

  Major (for rheumatoid arthritis)
• Side effects

  Mild (for Overall) (cognitive impairment)
• Adherence

  Usually
• Burden

  A little hard to take

Cost: < $25 monthly

• Effectiveness

  Moderate (for rheumatoid arthritis)
• Side effects

  Mild (for Overall) (cognitive impairment)
• Adherence

  Always
• Burden

  A little hard to take

Dosage: 20 mg Weekly

Advice & Tips: Methotrexate injections have been more beneficial than the oral form. The side effects are way less on injections. It still makes me feel slow and sleepy for a day or two after but not nauseous. When I was taking the oral form I would always only be able to sleep for six hours, then have to take a nap two hours after I would get up the day after I took the weekly dose. I had to stop taking my shot because I got a lung infection.

Cost: < $25 monthly

• Effectiveness

  Moderate (for Crohn's disease)
• Effectiveness

  Major (for rheumatoid arthritis)
• Side effects

  Moderate (for Overall) (grogginess)
• Adherence

  Always
• Burden

  Not at all hard to take

Dosage: 25 mg Weekly

Advice & Tips: Allow time to adjust after taking it for tiredness and very groggy and hard to focus. It is good for getting more than usual sleep.

Cost: $25-49 monthly