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Entacapone is an inhibitor of catechol-O-methyltransferase (COMT) and is used as an adjunct treatment for patients taking levodopa and carbidopa for Parkinson’s Disease who experience the signs and symptoms of end-of-dose “wearing-off”.
Advice & Tips:
Must be taken with C/L dosage. My effects vary with duration, but I have bad off time wear off; which is why i am trying DBS.
Cost:
< $25 monthly
0helpful marks
Jan 15, 2017
(Started Mar 20, 2010)
Effectiveness
Major
(for wearing off effect)
Effectiveness
Major
(for Parkinson's disease)
Side effects
None
Adherence
Always
Burden
Not at all hard to take
Dosage:
400 mg
Daily
Advice & Tips:
I have not been on at 10 PM for some time (a year or two or more). But I no longer take comtan because I have had DBS.
Cost:
$25-49 monthly
Side effects:
orange colored urine
May 22, 2010
(Started Mar 20, 2010)
Effectiveness
Major
(for wearing off effect)
Side effects
Mild
(orange colored urine)
Adherence
Always
Burden
Not at all hard to take
Dosage:
600 mg
Daily
Advice & Tips:
Since going to three doses a day, I frequently have no off time, from about half an hour after I take the medication first thing in the AM, until 8 or 9 at night. Sometimes I"m still on at 10 PM when I go to bed.
Cost:
$25-49 monthly
Side effects:
orange colored urine
0helpful marks
Feb 24, 2016
(Started Feb 17, 2012)
Effectiveness
Major
(for Parkinson's disease)
Side effects
None
Adherence
Always
Burden
A little hard to take
Dosage:
800 mg
Daily
0helpful marks
Last updated:
Showing 3 of 17 patient evaluations for Entacapone
