9 patient evaluations for Venlafaxine XR

May 2, 2014 (Started Jan 15, 2011)

  • Effectiveness
    Major (for chronic pain)
  • Effectiveness
    Major (for peripheral neuropathy)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily
Advice & Tips: Stopped taking it in a.m. And now take at hs. Helps with peripheral neuropathy. Cut down on drowsiness in am.

Jan 12, 2014 (Started Jan 15, 2011)

  • Effectiveness
    Moderate (for chronic pain)
  • Effectiveness
    Major (for peripheral neuropathy)
  • Side effects
    Mild (dry mouth)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 75 mg Daily

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Aug 15, 2013 (Started Jul 01, 2011)

  • Effectiveness
    Major (for agoraphobia)
  • Side effects
    Severe (elevated blood pressure)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 37.5 mg Daily
Advice & Tips: Monitor blood pressure, which may increase even after taking it for years. It generally made me calm. I forget to take it one day and I was very sleepy and groggy for a day. Going off of it was difficult: I had to do it very slowly, going down about 1 mg per day til I was completely off of it.
Cost: < $25 monthly

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Feb 7, 2013 (Started Oct 04, 2009)

  • Effectiveness
    Moderate (for generalized anxiety disorder)
  • Effectiveness
    Can't tell (for persistent depressive disorder (dysthymia))
  • Effectiveness
    Moderate (for chronic idiopathic axonal polyneuropathy)
  • Side effects
    Moderate (vivid nightmares, sleepiness, somnolence, apathy, orthostatic hypotension, sexual dysfunction, tachycardia (fast heart rate))
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 24.75 mg Daily
Advice & Tips: Effects both positive and adverse, both expected and unexpected, are pretty noticeable. Venlafaxine effects appear and fade much more rapidly than with SSRIs, and may change over time. By the time I stopped, I had been down to the lowest available dose of 25mg daily, which still seemed necessary for mood control, for a long time. It's been mostly helpful, and rarely burdensome except for the way it multiplies the effects of alcohol. Best unexpected benefit: mood control (less panicky/angry responses to cognitive dissonance). Intolerable imputed effect: Vividly unpleasant dreams, waking hyperventilating.
Cost: < $25 monthly
Side effects: excessive daytime sleepiness (somnolence), sleepiness, somnolence, orthostatic hypotension, sexual dysfunction, apathy, tachycardia (fast heart rate)

Mar 1, 2010 (Started Oct 04, 2009)

  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Moderate (for anxious mood)
  • Side effects
    Mild (sleepiness, somnolence, apathy, orthostatic hypotension, sexual dysfunction, tachycardia (fast heart rate))
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 37.5 mg Daily
Advice & Tips: Adverse effects now virtually disappear for me at 25 mg daily. This could change: some effects like the pounding in the ears at night or postural hypotension had previously disappeared at 37.5 mg; alarmingly rapid heart rate appeared over time at the same dosage (possibly associated with the transient hypotension). I'm still getting the good effects for the neuropathy, and the drug seems to act synergetically with cannabis in this area. The hypotension effect is probably aggravated by alcohol.
Cost: < $25 monthly
Side effects: excessive daytime sleepiness (somnolence), sleepiness, somnolence, orthostatic hypotension, sexual dysfunction, apathy, tachycardia (fast heart rate)

Nov 13, 2009 (Started Oct 04, 2009)

  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Can't tell (for anxious mood)
  • Side effects
    Mild (sleepiness, somnolence, apathy, orthostatic hypotension, sexual dysfunction)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 37.5 mg Daily
Advice & Tips: Venlaxafine seemed effective (within limits) for peripheral neuropathy and positive for relief of depression. Physical adverse effects at this dosage seemed minimal if any. Unresolved: Did this drug bliss me out too much, keeping me passive and lazy? And did it make me more suddenly irritable? I quit because of a pharmacy restriction (ironically based on the fact that I was taking "too little" of the drug), and will resume the trial once I talk to my primary provider in about 10 days.
Cost: < $25 monthly
Side effects: excessive daytime sleepiness (somnolence), sleepiness, somnolence, orthostatic hypotension, sexual dysfunction, apathy, tachycardia (fast heart rate)

Oct 28, 2009 (Started Oct 04, 2009)

  • Effectiveness
    Major (for anxious mood)
  • Effectiveness
    Moderate (for depressed mood)
  • Side effects
    Moderate (sleepiness, somnolence, apathy, orthostatic hypotension, sexual dysfunction)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 37.5 mg Daily
Advice & Tips: Venlafaxine by itself seems both to increase my alertness and to bliss me out a little too much; I get lethargic at 75 mg daily. Even at 37.5 mg, I've added (after a bit of research) my previous low dose of bupropion (25 mg) back into the mix as a counterbalancing "upper". Although intermittent, I'm seeing some direct effects on the depression: e.g., posture as well as mood.
Cost: < $25 monthly
Side effects: excessive daytime sleepiness (somnolence), sleepiness, somnolence, orthostatic hypotension, sexual dysfunction, apathy, tachycardia (fast heart rate)

  • 0 helpful marks
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Showing 3 of 9 patient evaluations for Venlafaxine XR