Bupropion

QuietGuy's Bupropion History (Stopped)
150 mg Daily Jan 23 - Mar 23, 2008
113 mg Daily Mar 23 - 27, 2008
75 mg Daily Mar 27 - May 05, 2008
113 mg Daily May 05 - 08, 2008
75 mg Daily May 08 - 11, 2008
100 mg Daily May 11 - Jun 18, 2008
82 mg Daily Jun 18 - 23, 2008
50 mg Daily Jun 23 - Aug 01, 2008
60 mg Daily Aug 01, 2008 - Feb 17, 2009
68 mg Daily Feb 17 - Aug 17, 2009
25 mg Daily Aug 17, 2009 - Sep 30, 2010
13 mg Daily Dec 19, 2011 - Jan 25, 2012
Stopped Side effects too severe Sep 30, 2010
Stopped Side effects too severe Jan 25, 2012

QuietGuy's Bupropion is for…

  • Persistent depressive disorder (dysthymia)
  • Fatigue
  • Problems concentrating

QuietGuy's side effects of Bupropion…

  • Hypersexuality Aug 5, 2009
  • Alcohol consumption Aug 5, 2009
  • Irritable and grouchy Sep 15, 2010
  • Craving alcohol Jan 23, 2008
  • Insomnia Aug 19, 2008
  • Bruxism (teeth grinding) Sep 1, 2011
  • Agitation with irritability Sep 15, 2011

Evaluations


Dec 19, 2011

Dosage
13 mg Daily
  • Effectiveness
    Can’t tell (for Fatigue)
  • Effectiveness
    Can’t tell (for Problems concentrating)
  • Effectiveness
    Moderate (for Persistent depressive disorder (dysthymia))
  • side effects
    Moderate (Hypersexuality, Alcohol consumption, Irritable and grouchy, feeling well, energetic, Craving alcohol, Sleeplessness, Insomnia, Bruxism (teeth grinding), Agitation with irritability)
  • Adherence
    Always
  • Burden
    A little hard to take
Advice & Tips
Titrated downward twice in two weeks for the usual adverse effects: hypersexuality, insomnia, craving alcohol, slight hyperacusis (ear pulse), mild teeth grinding.
Cost
< $25 monthly

Sep 30, 2010

Dosage
25 mg Daily
  • Effectiveness
    Can’t tell (for Depressed mood)
  • Effectiveness
    Can’t tell (for Fatigue)
  • Effectiveness
    Can’t tell (for Problems concentrating)
  • side effects
    Moderate (Hypersexuality, Alcohol consumption, Irritable and grouchy, feeling well, energetic, Craving alcohol, Sleeplessness, Insomnia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips
At prescribed doses, induced hypomania. At lower doses, may have helped with concentration, depression and fatigue—or not. Did keep me awake if I took it after noon. Stopped because I came to see it as contributing to irritability. This gets complicated, because giving it up can do the same—perhaps because it's habituating/addictive. Be all that as it may, I feel better off without it now.
Cost
< $25 monthly

Aug 5, 2009

Dosage
68 mg Daily
  • Effectiveness
    Moderate (for Fatigue)
  • Effectiveness
    Can’t tell (for Problems concentrating)
  • Effectiveness
    Moderate (for Depressed mood)
  • side effects
    Moderate (Hypersexuality, Alcohol consumption, feeling well, energetic, Craving alcohol, Sleeplessness, Insomnia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips
Dosage, dosage, dosage! Be observant about effects, report them, and work with your prescriber to optimize the dose. Micromanage as needed. Use the instant mood readings to spot trends. Get multiiple prescriptions (in different dosages) if that's what you need to manage and your prescriber will cooperate.
Cost
< $25 monthly

Feb 21, 2009

Dosage
68 mg Daily
  • Effectiveness
    Moderate (for Problems concentrating)
  • side effects
    Mild (feeling well, energetic, Craving alcohol, Sleeplessness, Insomnia)
  • Adherence
    Always
  • Burden
    A little hard to take
Advice & Tips
Be vigilant about effects, particularly hypomania, and how they relate to dosage and timing of dose. Charting your instant mood can be very helpful for this. It works for me to adjust the dose according to my pattern of good and bad days, and this helps a lot in evening out my moods. If you notice tinnitus, particularly pounding in the ears at night, check out other causes; bupropion may be making you more sensitive to something that you can fix with an earwash or other measures.
Cost
< $25 monthly

Nov 10, 2008

Dosage
60 mg Daily
  • Effectiveness
    Major (for Problems concentrating)
  • side effects
    Moderate (feeling well, energetic, Craving alcohol, Sleeplessness, Insomnia)
  • Adherence
    Always
  • Burden
    A little hard to take
Advice & Tips
Dosage, dosage, dosage! Observe the effects, and work with your prescriber to find the dose that's best for you (assuming this is the right drug for you, which of course may not be the case). Through quite a bit of trial and error, I arrived at a dose of about 60 mg a day, which I manage by taking 50 mg (half a 100 mg tablet) 4 days a week and 75 mg (the smallest tab available) 3 days a week. I'm generally sensitive to medications, and many people tolerate and benefit from much more, but the same principle applies: weigh the cost and benefits and see if you can optimize their balance through adjusting dosage (always in consultation with your prescriber).
Cost
< $25 monthly

Aug 19, 2008

Dosage
60 mg Daily
  • Effectiveness
    Moderate (for Problems concentrating)
  • side effects
    Moderate (feeling well, energetic, Craving alcohol, Sleeplessness, Insomnia)
  • Adherence
    Always
  • Burden
    A little hard to take
Advice & Tips
This is in my experience and according to a friend's report a "speedy" drug. Watch effects carefully and be prepared to adjust dosage as needed.
Cost
< $25 monthly

About Bupropion (Prescription Drug)

Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder, and as an adjunct in smoking cessation. It may also be used for attention-deficit/hyperactivity and bipolar disorders.

Learn more about Bupropion in our Bupropion Community Report.