Multiple system atrophy

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What is multiple system atrophy?

Multiple system atrophy (MSA) is a degenerative neurological disorder. MSA is associated with the degeneration of nerve cells in specific areas of the brain. This cell degeneration causes problems with movement, balance and autonomic functions of the body such as bladder control.

Common symptoms reported by people with multiple system atrophy

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, insomnia, fatigue, and pain) regardless of condition.
Last updated:

Treatments taken by people with multiple system atrophy

You’ve tried
Treatment name(s)
Type
How many have tried
Tried for
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Treatment name(s)

(Sinemet)
Type
Prescription Drug
How many have tried
22
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Treatment name(s)

(Florinef)
Type
Prescription Drug
How many have tried
12
Tried for
multiple system atrophy (12)
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Treatment name(s)

(Klonopin)
Type
Prescription Drug
How many have tried
10
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Treatment name(s)

(Symmetrel)
Type
Prescription Drug
How many have tried
4
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Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
4
Tried for
Depressed mood (3) Pain (1)
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Treatment name(s)

(Rytary XR)
Type
Prescription Drug
How many have tried
3
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Treatment name(s)

(Lexapro)
Type
Prescription Drug
How many have tried
3
Tried for
Depressed mood (2) Anxious mood (1)
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Treatment name(s)

(Xanax)
Type
Prescription Drug
How many have tried
2
Tried for
Anxious mood (2)
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Treatment name(s)

(Elavil)
Type
Prescription Drug
How many have tried
2
Tried for
Insomnia (2)
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Treatment name(s)

(Mylan-Baclofen)
Type
Prescription Drug
How many have tried
2
Tried for
Pain (1) Stiffness/Spasticity (1)

Data from patients with multiple system atrophy, who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

Compare treatments taken by people with multiple system atrophy

You’ve tried
Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Check to add this treatment to your profile
Treatment name(s)

(Sinemet)
Perceived effectiveness
for multiple system atrophy (9 evaluations)
Side effects
Allergic reaction Constipation 3 more
Total evaluations
13
Check to add this treatment to your profile
Treatment name(s)

(Florinef)
Perceived effectiveness
for multiple system atrophy (8 evaluations)
Side effects
Could not walk for 6-8 hour afterwards Fluid retention weight gain
Total evaluations
8
Tried for
multiple system atrophy (12)
Check to add this treatment to your profile
Treatment name(s)

(Klonopin)
Perceived effectiveness
for multiple system atrophy (2 evaluations)
Side effects
Drowsy in a.m. Morning sleepiness
Total evaluations
4
Check to add this treatment to your profile
Treatment name(s)

(Symmetrel)
Perceived effectiveness
for multiple system atrophy (1 evaluation)
Side effects
Dizziness and feeling faint
Total evaluations
1
Check to add this treatment to your profile
Treatment name(s)

(Cymbalta)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Tried for
Depressed mood (3) Pain (1)
Check to add this treatment to your profile
Treatment name(s)

(Rytary XR)
Perceived effectiveness
for multiple system atrophy (2 evaluations)
Side effects
Bruxism (teeth grinding) Unresponsiveness
Total evaluations
2
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Treatment name(s)

(Lexapro)
Perceived effectiveness
for Depressed mood (1 evaluation)
Side effects
Excessive daytime sleepiness (somnolence)
Total evaluations
2
Tried for
Depressed mood (2) Anxious mood (1)
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Treatment name(s)

(Xanax)
Perceived effectiveness
for Anxious mood (2 evaluations)
Side effects
Drowsiness
Total evaluations
2
Tried for
Anxious mood (2)
Check to add this treatment to your profile
Treatment name(s)

(Elavil)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Tried for
Insomnia (2)
Check to add this treatment to your profile
Treatment name(s)

(Mylan-Baclofen)
Perceived effectiveness
for Pain (1 evaluation)
Side effects
Shortness of breath (dyspnea)
Total evaluations
2
Tried for
Pain (1) Stiffness/Spasticity (1)
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with multiple system atrophy, who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

Who has multiple system atrophy on PatientsLikeMe?


Age
Age Proportion # of patients
<20 0
20s 11
30s 26
40s 47
50s 167
60s 248
70+ 159
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 8
20-29 years 14
30-39 years 31
40-49 years 90
50-59 years 157
60-69 years 72
70+ years 13

Sex

Distribution of sex

52% Female
48% Male

Types
Condition Types Proportion # of patients
Multiple System Atrophy (MSA) 301
Olivopontocerebellar atrophy (OPCA/MSA-c) 105
Shy-Drager Syndrome (MSA-a) 61
Striatonigral degeneration (MSA-p) 82
Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 400
Not Diagnosed 61

These charts show data from MSA patients who have completed their condition history
Last updated: