Cataplexy

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By sharing your stories and data, you will:
  • help each other live better and uncover the best ways to manage your health today
  • help researchers shorten the path to new treatments tomorrow

How much good can your data do? A whole lot, as co-founder Jamie Heywood explains in this video.

What is cataplexy?

Cataplexy is the sudden loss of muscle tone that is triggered by the experience of an intense emotion. Cataplexy is the result of an absence of a neurotransmitter in the hypothalamus known as hypocretin or orexin. It is often associated with narcolepsy but is seen in other pathological conditions.

Common symptoms reported by people with cataplexy

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, insomnia, fatigue, and pain) regardless of condition.
Last updated:

Treatments taken by people with cataplexy

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Xyrem)
Type
Prescription Drug
How many have tried
10
Tried for
cataplexy (10)
Treatment name(s)

(Effexor XR)
Type
Prescription Drug
How many have tried
5
Tried for
cataplexy (4) Depressed mood (1)
Treatment name(s)

(Adderall)
Type
Prescription Drug
How many have tried
3
Tried for
Fatigue (3)
Treatment name(s)

(Elavil)
Type
Prescription Drug
How many have tried
2
Tried for
Insomnia (2) Pain (2)
Treatment name(s)

(Nuvigil)
Type
Prescription Drug
How many have tried
2
Tried for
cataplexy (1) Fatigue (1)
Treatment name(s)

(Wellbutrin XL)
Type
Prescription Drug
How many have tried
2
Tried for
Depressed mood (2) Anxious mood (1)
Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
2
Tried for
Depressed mood (2)
Treatment name(s)

(Provigil)
Type
Prescription Drug
How many have tried
2
Tried for
cataplexy (1) Fatigue (1)
Treatment name(s)

(Xanax)
Type
Prescription Drug
How many have tried
1
Tried for
Anxious mood (1)
Treatment name(s)

(Mylan-Baclofen)
Type
Prescription Drug
How many have tried
1
Tried for
cataplexy (1)

Data from patients with cataplexy, who reported starting treatments within the last 5 years.
Last updated:

Compare treatments taken by people with cataplexy

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Xyrem)
Perceived effectiveness
for cataplexy (4 evaluations)
Side effects
Nausea Brain fog 4 more
Total evaluations
4
Tried for
cataplexy (10)
Treatment name(s)

(Effexor XR)
Perceived effectiveness
for cataplexy (6 evaluations)
Side effects
Nausea and dizziness Tiredness
Total evaluations
6
Tried for
cataplexy (4) Depressed mood (1)
Treatment name(s)

(Adderall)
Perceived effectiveness
for Fatigue (1 evaluation)
Side effects
Heart rate increased
Total evaluations
1
Tried for
Fatigue (3)
Treatment name(s)

(Elavil)
Perceived effectiveness
for Insomnia (3 evaluations)
Side effects
Excessive daytime sleepiness (somnolence)
Total evaluations
3
Tried for
Insomnia (2) Pain (2)
Treatment name(s)

(Nuvigil)
Perceived effectiveness
for Fatigue (1 evaluation)
Side effects
Total evaluations
1
Tried for
cataplexy (1) Fatigue (1)
Treatment name(s)

(Wellbutrin XL)
Perceived effectiveness
for Depressed mood (1 evaluation)
Side effects
Total evaluations
1
Tried for
Depressed mood (2) Anxious mood (1)
Treatment name(s)

(Cymbalta)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Tried for
Depressed mood (2)
Treatment name(s)

(Provigil)
Perceived effectiveness
for cataplexy (1 evaluation)
Side effects
Headaches in morning
Total evaluations
1
Tried for
cataplexy (1) Fatigue (1)
Treatment name(s)

(Xanax)
Perceived effectiveness
for Anxious mood (1 evaluation)
Side effects
Total evaluations
1
Tried for
Anxious mood (1)
Treatment name(s)

(Mylan-Baclofen)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Tried for
cataplexy (1)
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with cataplexy, who reported starting treatments within the last 5 years.
Last updated:

Who has cataplexy on PatientsLikeMe?


Age
Age Proportion # of patients
<20 0
20s 16
30s 27
40s 42
50s 17
60s 10
70+ 2
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 33
20-29 years 19
30-39 years 17
40-49 years 11
50-59 years 4
60-69 years 0
70+ years 0

Sex

Distribution of sex

82% Female
18% Male

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 87
Not Diagnosed 5

These charts show data from cataplexy patients who have completed their condition history
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