Monoclonal gammopathy of undetermined significance

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What is monoclonal gammopathy of undetermined significance?

Monoclonal gammopathy of undetermined significance is a condition in which a paraprotein is found in the blood during standard laboratory tests. MGUS usually is asymptomatic, but peripheral neuropathy can occur.

Common symptoms reported by people with monoclonal gammopathy of undetermined significance

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
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Treatments taken by people with monoclonal gammopathy of undetermined significance

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
4
Tried for
depressed mood (3) Pain (2)
Treatment name(s)

(Lyrica)
Type
Prescription Drug
How many have tried
3
Tried for
Pain (3)
Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
3
Tried for
Pain (3)
Treatment name(s)

(Elavil)
Type
Prescription Drug
How many have tried
2
Tried for
Pain (2)
Treatment name(s)
Type
Procedures
How many have tried
2
Treatment name(s)

(Tylenol)
Type
Over the Counter Drug
How many have tried
1
Tried for
Pain (1)
Treatment name(s)

(Albuterol Inhaler)
Type
Prescription Drug
How many have tried
1
Tried for
fatigue (1)
Treatment name(s)

(Xanax)
Type
Prescription Drug
How many have tried
1
Tried for
anxious mood (1)
Treatment name(s)

(Plus CBD Oil)
Type
Other
How many have tried
1
Tried for
Pain (1)
Treatment name(s)

(Valium)
Type
Prescription Drug
How many have tried
1
Tried for
anxious mood (1)

Data from patients with monoclonal gammopathy of undetermined significance, who reported starting treatments within the last 5 years.
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Compare treatments taken by people with monoclonal gammopathy of undetermined significance

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for depressed mood (2 evaluations)
Side effects
nightmares tiredness 1 more
Total evaluations
4
Tried for
depressed mood (3) Pain (2)
Treatment name(s)

(Lyrica)
Perceived effectiveness
for Pain (5 evaluations)
Side effects
apathy cramps in toes 10 more
Total evaluations
5
Tried for
Pain (3)
Treatment name(s)

(Ultram)
Perceived effectiveness
for Pain (3 evaluations)
Side effects
tired for a few hours after treatment
Total evaluations
3
Tried for
Pain (3)
Treatment name(s)

(Elavil)
Perceived effectiveness
for Pain (1 evaluation)
Side effects
dry mouth tiredness
Total evaluations
2
Tried for
Pain (2)
Treatment name(s)
Perceived effectiveness
for monoclonal gammopathy of undetermined significance (2 evaluations)
Side effects
Hospitalization soreness
Total evaluations
2
Treatment name(s)

(Tylenol)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Tried for
Pain (1)
Treatment name(s)

(Albuterol Inhaler)
Perceived effectiveness
for fatigue (2 evaluations)
Side effects
jumpiness (startling easily)
Total evaluations
2
Tried for
fatigue (1)
Treatment name(s)

(Xanax)
Perceived effectiveness
for anxious mood (1 evaluation)
Side effects
drowsiness
Total evaluations
1
Tried for
anxious mood (1)
Treatment name(s)

(Plus CBD Oil)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Tried for
Pain (1)
Treatment name(s)

(Valium)
Perceived effectiveness
No evaluations
Side effects
No evaluations
Total evaluations
0
Tried for
anxious mood (1)
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with monoclonal gammopathy of undetermined significance, who reported starting treatments within the last 5 years.
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Who has monoclonal gammopathy of undetermined significance on PatientsLikeMe?


Age
Age Proportion # of patients
<20 1
20s 0
30s 5
40s 31
50s 70
60s 63
70+ 35
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 1
20-29 years 0
30-39 years 6
40-49 years 17
50-59 years 17
60-69 years 14
70+ years 0

Sex

Distribution of sex

80% Female
20% Male

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 103
Not Diagnosed 3

These charts show data from MGUS patients who have completed their condition history
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