Mixed connective tissue disease

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What is mixed connective tissue disease?

Mixed connective tissue disease is an uncommon autoimmune disorder that causes overlapping features of primarily three connective tissue diseases: lupus, scleroderma and polymyositis. It may be preceded by Raynaud's phenomenon and have features of rheumatoid arthritis.

Common symptoms reported by people with mixed connective tissue disease

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
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Treatments taken by people with mixed connective tissue disease

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Plaquenil)
Type
Prescription Drug
How many have tried
68
Treatment name(s)

(Deltasone)
Type
Prescription Drug
How many have tried
26
Treatment name(s)

(Apo-Methotrexate)
Type
Prescription Drug
How many have tried
20
Treatment name(s)

(Folic Acid Prescription)
Type
Supplement
How many have tried
16
Treatment name(s)

(Neurontin)
Type
Prescription Drug
How many have tried
13
Treatment name(s)

(Advil)
Type
Over the Counter Drug
How many have tried
8
Treatment name(s)

(Naprosyn)
Type
Prescription Drug
How many have tried
8
Treatment name(s)

(Flexeril)
Type
Prescription Drug
How many have tried
7
Treatment name(s)

(Mobic)
Type
Prescription Drug
How many have tried
7
Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
7
Tried for
pain (7)

Data from patients with mixed connective tissue disease, who reported starting treatments within the last 5 years.
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Compare treatments taken by people with mixed connective tissue disease

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Plaquenil)
Perceived effectiveness
for mixed connective tissue disease (22 evaluations)
Side effects
nausea blurry vision 27 more
Total evaluations
29
Treatment name(s)

(Deltasone)
Perceived effectiveness
for mixed connective tissue disease (13 evaluations)
Side effects
weight gain headaches 27 more
Total evaluations
21
Treatment name(s)

(Apo-Methotrexate)
Perceived effectiveness
for mixed connective tissue disease (7 evaluations)
Side effects
nausea fatigue 13 more
Total evaluations
14
Treatment name(s)

(Folic Acid Prescription)
Perceived effectiveness
for mixed connective tissue disease (6 evaluations)
Side effects
Total evaluations
6
Treatment name(s)

(Neurontin)
Perceived effectiveness
for pain (8 evaluations)
Side effects
drowsiness weight gain 1 more
Total evaluations
9
Treatment name(s)

(Advil)
Perceived effectiveness
No evaluations
Side effects
liver damage
Total evaluations
1
Treatment name(s)

(Naprosyn)
Perceived effectiveness
for mixed connective tissue disease (6 evaluations)
Side effects
abdominal pain gastric ulcer 2 more
Total evaluations
6
Treatment name(s)

(Flexeril)
Perceived effectiveness
for pain (12 evaluations)
Side effects
drowsiness constipation 8 more
Total evaluations
12
Treatment name(s)

(Mobic)
Perceived effectiveness
for pain (3 evaluations)
Side effects
water retention in hands and feet
Total evaluations
3
Treatment name(s)

(Ultram)
Perceived effectiveness
for pain (2 evaluations)
Side effects
brain fog drowsiness 1 more
Total evaluations
2
Tried for
pain (7)
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with mixed connective tissue disease, who reported starting treatments within the last 5 years.
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Who has mixed connective tissue disease on PatientsLikeMe?


Age
Age Proportion # of patients
<20 9
20s 44
30s 159
40s 315
50s 345
60s 167
70+ 28
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 62
20-29 years 80
30-39 years 134
40-49 years 106
50-59 years 44
60-69 years 11
70+ years 0

Distribution of sex

Sex
Sex Proportion # of patients
Male 41
Female 1,034

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 546
Not Diagnosed 29

These charts show data from mixed connective tissue disease patients who have completed their condition history
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