Mixed connective tissue disease

We’re all in this for good.

By sharing your stories and data, you will:
  • help each other live better and uncover the best ways to manage your health today
  • help researchers shorten the path to new treatments tomorrow

How much good can your data do? A whole lot, as co-founder Jamie Heywood explains in this video.

What is mixed connective tissue disease?

Mixed connective tissue disease is an uncommon autoimmune disorder that causes overlapping features of primarily three connective tissue diseases: lupus, scleroderma and polymyositis. It may be preceded by Raynaud's phenomenon and have features of rheumatoid arthritis.

Common symptoms reported by people with mixed connective tissue disease

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
Last updated:

Treatments taken by people with mixed connective tissue disease

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Plaquenil)
Type
Prescription Drug
How many have tried
66
Treatment name(s)

(Deltasone)
Type
Prescription Drug
How many have tried
29
Treatment name(s)

(Apo-Methotrexate)
Type
Prescription Drug
How many have tried
20
Treatment name(s)

(Folic Acid Prescription)
Type
Supplement
How many have tried
14
Treatment name(s)

(Neurontin)
Type
Prescription Drug
How many have tried
11
Treatment name(s)

(Advil)
Type
Over the Counter Drug
How many have tried
10
Treatment name(s)

(Naprosyn)
Type
Prescription Drug
How many have tried
10
Treatment name(s)

(Ultram)
Type
Prescription Drug
How many have tried
7
Tried for
pain (7)
Treatment name(s)

(Flexeril)
Type
Prescription Drug
How many have tried
6
Treatment name(s)

(Mobic)
Type
Prescription Drug
How many have tried
6

Data from patients with mixed connective tissue disease, who reported starting treatments within the last 5 years.
Last updated:

Compare treatments taken by people with mixed connective tissue disease

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Plaquenil)
Perceived effectiveness
for mixed connective tissue disease (22 evaluations)
Side effects
nausea blurry vision 28 more
Total evaluations
29
Treatment name(s)

(Deltasone)
Perceived effectiveness
for mixed connective tissue disease (17 evaluations)
Side effects
weight gain headaches 29 more
Total evaluations
27
Treatment name(s)

(Apo-Methotrexate)
Perceived effectiveness
for mixed connective tissue disease (8 evaluations)
Side effects
nausea diarrhea 13 more
Total evaluations
15
Treatment name(s)

(Folic Acid Prescription)
Perceived effectiveness
for mixed connective tissue disease (7 evaluations)
Side effects
Total evaluations
7
Treatment name(s)

(Neurontin)
Perceived effectiveness
for pain (7 evaluations)
Side effects
drowsiness weight gain 1 more
Total evaluations
8
Treatment name(s)

(Advil)
Perceived effectiveness
No evaluations
Side effects
liver damage
Total evaluations
1
Treatment name(s)

(Naprosyn)
Perceived effectiveness
for mixed connective tissue disease (6 evaluations)
Side effects
abdominal pain gastrointestinal (GI) bleeding 1 more
Total evaluations
6
Treatment name(s)

(Ultram)
Perceived effectiveness
for pain (2 evaluations)
Side effects
brain fog drowsiness 1 more
Total evaluations
2
Tried for
pain (7)
Treatment name(s)

(Flexeril)
Perceived effectiveness
for pain (10 evaluations)
Side effects
drowsiness constipation 8 more
Total evaluations
10
Treatment name(s)

(Mobic)
Perceived effectiveness
for pain (3 evaluations)
Side effects
water retention in hands and feet
Total evaluations
3
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with mixed connective tissue disease, who reported starting treatments within the last 5 years.
Last updated:

Who has mixed connective tissue disease on PatientsLikeMe?


Age
Age Proportion # of patients
<20 8
20s 43
30s 162
40s 304
50s 329
60s 161
70+ 23
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 63
20-29 years 80
30-39 years 133
40-49 years 105
50-59 years 43
60-69 years 11
70+ years 0

Distribution of sex

Sex
Sex Proportion # of patients
Male 40
Female 995

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 536
Not Diagnosed 29

These charts show data from mixed connective tissue disease patients who have completed their condition history
Last updated: