What is major depressive disorder?

Major depressive disorder, also known as clinical depression, is marked by depressed mood, inactivity, lack of interest, insomnia, feelings of worthlessness, diminished ability to think, and may include thoughts of suicide.

How do members experience major depressive disorder?

Top 5 symptoms reported by people with major depressive disorder*

*Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.

Top treatments taken by people for major depressive disorder*

*Data from patients with major depressive disorder, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.

Compare treatments taken by people with major depressive disorder*

Treatment
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment

(Wellbutrin)
Perceived effectiveness
for major depressive disorder (43 evaluations)
Side effects
hyperactivity nausea 16 more
Total evaluations
43
Tried for
major depressive disorder (92)
Treatment

(Zoloft)
Perceived effectiveness
for major depressive disorder (28 evaluations)
Side effects
suicidal thoughts or urges bloodshot eyes 12 more
Total evaluations
28
Tried for
major depressive disorder (75)
Treatment

(Cymbalta)
Perceived effectiveness
for major depressive disorder (39 evaluations)
Side effects
abdominal pain bladder problems 7 more
Total evaluations
39
Tried for
major depressive disorder (72)
Treatment

(Effexor XR)
Perceived effectiveness
for major depressive disorder (23 evaluations)
Side effects
dizziness increased anxiety 25 more
Total evaluations
23
Tried for
major depressive disorder (63)
Treatment

(Lexapro)
Perceived effectiveness
for major depressive disorder (26 evaluations)
Side effects
brain fog diarrhea 28 more
Total evaluations
26
Tried for
major depressive disorder (61)

*Data from patients with major depressive disorder, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.

Who has major depressive disorder on PatientsLikeMe?

Age

Age Proportion # of patients
<20 174
20s 3,039
30s 8,326
40s 13,571
50s 17,658
60s 14,551
70+ 5,103

Distribution of sex

Sex

Sex Proportion # of patients
Male 13,346
Female 48,999