Major depressive disorder

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What is major depressive disorder?

Major depressive disorder, also known as clinical depression, is marked by depressed mood, inactivity, lack of interest, insomnia, feelings of worthlessness, diminished ability to think, and may include thoughts of suicide.

Common symptoms reported by people with major depressive disorder

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition.
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Treatments taken by people for major depressive disorder

Treatment name(s)
Type
How many have tried
Tried for
Treatment name(s)

(Wellbutrin)
Type
Prescription Drug
How many have tried
15732
Tried for
major depressive disorder (547)
Treatment name(s)

(Talk therapy)
Type
Psychotherapy
How many have tried
23175
Tried for
major depressive disorder (381)
Treatment name(s)

(Cymbalta)
Type
Prescription Drug
How many have tried
11642
Tried for
major depressive disorder (364)
Treatment name(s)

(Effexor XR)
Type
Prescription Drug
How many have tried
15328
Tried for
major depressive disorder (327)
Treatment name(s)

(Zoloft)
Type
Prescription Drug
How many have tried
18811
Tried for
major depressive disorder (319)
Treatment name(s)

(Lexapro)
Type
Prescription Drug
How many have tried
10290
Tried for
major depressive disorder (262)
Treatment name(s)

(Prozac)
Type
Prescription Drug
How many have tried
18114
Tried for
major depressive disorder (258)
Treatment name(s)

(Celexa)
Type
Prescription Drug
How many have tried
10662
Tried for
major depressive disorder (150)

Data from patients with major depressive disorder, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.
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Compare treatments taken by people with major depressive disorder

Treatment name(s)
Perceived effectiveness
Side effects
Total evaluations
Tried for
Treatment name(s)

(Wellbutrin)
Perceived effectiveness
for major depressive disorder (299 evaluations)
Side effects
dry mouth headaches 139 more
Total evaluations
329
Tried for
major depressive disorder (547)
Treatment name(s)

(Talk therapy)
Perceived effectiveness
for major depressive disorder (200 evaluations)
Side effects
anxious mood flashbacks 39 more
Total evaluations
231
Tried for
major depressive disorder (381)
Treatment name(s)

(Cymbalta)
Perceived effectiveness
for major depressive disorder (208 evaluations)
Side effects
dry mouth weight gain 109 more
Total evaluations
231
Tried for
major depressive disorder (364)
Treatment name(s)

(Effexor XR)
Perceived effectiveness
for major depressive disorder (229 evaluations)
Side effects
dry mouth nausea 118 more
Total evaluations
247
Tried for
major depressive disorder (327)
Treatment name(s)

(Zoloft)
Perceived effectiveness
for major depressive disorder (214 evaluations)
Side effects
weight gain decreased sex drive (libido) 107 more
Total evaluations
227
Tried for
major depressive disorder (319)
Treatment name(s)

(Lexapro)
Perceived effectiveness
for major depressive disorder (154 evaluations)
Side effects
decreased sex drive (libido) dry mouth 83 more
Total evaluations
156
Tried for
major depressive disorder (262)
Treatment name(s)

(Prozac)
Perceived effectiveness
for major depressive disorder (160 evaluations)
Side effects
nausea decreased sex drive (libido) 76 more
Total evaluations
171
Tried for
major depressive disorder (258)
Treatment name(s)

(Celexa)
Perceived effectiveness
for major depressive disorder (89 evaluations)
Side effects
nausea dizziness 44 more
Total evaluations
92
Tried for
major depressive disorder (150)
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Data from patients with major depressive disorder, who have ever reported treatments, ordered by their reporting frequency during the last 5 years.
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Who has major depressive disorder on PatientsLikeMe?

  • 43 new patients joined this month
  • 31688 say MDD is their primary condition

Age
Age Proportion # of patients
<20 261
20s 4139
30s 9283
40s 14067
50s 16844
60s 10931
70+ 2597
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 8822
20-29 years 3724
30-39 years 2725
40-49 years 1749
50-59 years 611
60-69 years 114
70+ years 19

Distribution of sex

Sex
Sex Proportion # of patients
Male 12050
Female 46375

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 23895
Not Diagnosed 2334

These charts show data from MDD patients who have completed their condition history
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