Brain Tissue Collection for Neuropathological Studies

Conditions Phase Intervention Type


Ages Eligible for Study
Genders Eligible for Study


Schizophrenia, Neuropathology, Neurochemistry, Substance Abuse, Bipolar Disorder, Aging, Normal Development, Depression, Anxiety Disorders, Suicide, Dementia, Neuropsychiatric Disorders, Tourettes Syndrome, and Normal Controls


National Institute of Mental Health (NIMH)

Inclusion Criteria

Brain tissue is needed from individuals suffering from a variety of neuropsychiatric
disorders, especially schizophrenia, but also anxiety disorders, suicide, bipolar disorder,
depression, Tourette's Syndrome, drug addictions (PCP, cocaine, alcohol, heroin or the
like) and any form of dementia. In addition, brains from normal individuals without a
history of neuropsychiatric disease will be needed for controls.

Exclusion Criteria

No living subjects are enrolled in this protocol. Tissue is obtained after death, with the
permission of next of kin, or from existing institutions with appropriate samples via an
MTA or other applicable agreement.

Brain tissue is excluded from collection if there is a previously known history of strokes,
lesions, or other major neuropathological abnormalities prior to the consenting process.

Detailed Description

The purpose of this study is to collect and study the brain tissue of deceased individuals to learn more about the nervous system and mental disorders. Information gained from donated tissue may lead to better treatments and potential cures for nervous system and mental disorders. This study will ask relatives of deceased individuals to donate the brains of their deceased relatives to allow further study of neurological and psychiatric disorders. We do not accept prospective donations....

Contacts and Locations

Please refer to this study by its identifier: NCT00001260


  • Office of the Chief Medical Examiner
    Washington, District of Columbia United States


  • National Institutes of Health Clinical Center, 9000 Rockville Pike
    Bethesda, Maryland United States

    Status: Recruiting

  • Office of the Chief Medical Examiner
    Fairfax, Virginia United States

    Status: Recruiting