Resistance to Vitamin D or Parathyroid Hormone

Conditions Phase Intervention Type


Ages Eligible for Study
12 months and up
Genders Eligible for Study


Calcium, Vitamin D, Calcitriol, Parathyroid, Cyclic AMP, and Rickets


National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Inclusion Criteria

Patients of any age or sex with vitamin D resistance, rickets, osteomalacia,
pseudohypoparathyroidism, pseudo-pseudohypoparathyroidism, or suspicion of these or related
disorders based upon the appropriateness of their problem to ongoing investigations.

Current investigations are focused primarily upon subjects with target tissue resistance to
1,25-dihydroxyvitamin D, pseudohypoparathyroidism, and pseudo-pseudohypoparathyroidism.

Exclusion Criteria

Detailed Description

Patients with confirmed or suspected conditions with a resistance to vitamin D or parathyroid hormone (PTH) will be admitted for diagnosis and treatment, and inclusion in other studies pertaining to similar conditions. This study will provide information about problems relating to calcium in the blood, urine, and bones. Patients in this study will undergo a general evaluation / check-up to give researchers an idea of each person's condition or disease. Patients will receive treatment based on their diagnosis and asked to provide specimen samples for further research studies.

Contacts and Locations

Please refer to this study by its identifier: NCT00001242


  • National Institutes of Health Clinical Center, 9000 Rockville Pike
    Bethesda, Maryland United States

    Status: Recruiting

    Contact info For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Overall Contact Backup

Lee S Weinstein, M.D.
(301) 402-2923