Studying Patients With Cystic Fibrosis and Other Pulmonary and Pancreatic Disorders

Conditions Phase Intervention Type
N/A

Eligibility

Ages Eligible for Study
4 years and up
Genders Eligible for Study
Both

Keywords

Cystic Fibrosis, Pancreatic Insufficiency, and Bronchiectasis

Sponsors

NIH
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Inclusion Criteria

Patients and family members with known or suspected CF and related disorders of the
respiratory tract or pancreas as defined by clinical presentation, sweat testing and/or
genotyping.

Willingness of patients, or guardian to give informed consent.

Exclusion Criteria

Age less than 4 years.

Concomitant medical, psychiatric or other problems which might complicate interpretation of
studies of CF, or for which we are unable to provide adequate care.

Detailed Description

Cystic fibrosis is a disease that affects many parts of the body, particularly the lungs and pancreas. The main purpose of this study is to further understand the natural history, clinical presentation, and genetics of cystic fibrosis. Patients with cystic fibrosis will be asked to participate in this study by undergoing standard medical tests and procedures. Patients will have a history taken and have a physical examination as well as blood tests, and a sweat test (a test for cystic fibrosis of the pancreas in which electrolytes are measured in collected sweat). Patients may also be asked to provide samples of urine, stool, and sputum for additional tests. More complicated procedures such as bronchoscopy or bronchoalveolar lavage may be required for diagnosis, treatment, or research purposes. Patients will receive appropriate treatment with antibiotics, pancreatic enzymes, vitamins, physiotherapy, and other agents. Medications may be given by mouth or injected into a vein. This study will provide patients with information on the prognosis of the disease as well as recommendations for management of cystic fibrosis. In addition this study will provide information to researchers which may be useful in other studies of cystic fibrosis.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00001223

Overall Contact Backup

Milica S Chernick, M.D.
(301) 496-3434

Locations

  • National Institutes of Health Clinical Center, 9000 Rockville Pike
    Bethesda, Maryland United States

    Status: Recruiting

    Contact info For more information at the NIH Clinical Center contact Patient Recruitment and Public Liaison Office (PRPL)
    800-411-1222xTTY8664111010