Dextromethorphan with Quinidine Treatment Report

Category: Prescription Drugs

Most Popular Types: Nuedexta, Neurodex, 07-AVR-123 OLE

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What is Dextromethorphan with Quinidine?

An example of Dextromethorphan with Quinidine

A dextromethorphan-quinidine combination was studied for its effect on inappropriate laughing and crying episodes experienced by some patients with brain injury or brain degeneration due to certain diseases. The incongruous laughing and crying episodes are due to pseudobulbar affect.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
46 16 Efficacy_major Efficacy_moderate Efficacy_none
18 5 Efficacy_moderate Efficacy_none
3 0
1 1 Efficacy_moderate
1 1 Efficacy_major
1 0

See all 60 patients currently taking Dextromethorphan with Quinidine

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Reported Side Effects

Side effects as an overall problem

Severe
 1
Moderate
 7
Mild
 3
None
 16

Commonly reported side effects, conditions, and hospitalizations associated with Dextromethorphan with Quinidine

2
1
1
1
1
1
See all 11 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Dextromethorphan with Quinidine. See all 18 dosages ►

  daily 1 cap(s) daily 2 cap(s) daily 2 mg daily 10 mg daily 20 mg daily 30 mg daily 40 mg daily 50 mg daily 60 mg daily
  5 Number of Patients: 5 3 Number of Patients: 3 8 Number of Patients: 8 4 Number of Patients: 4 6 Number of Patients: 6 11 Number of Patients: 11 6 Number of Patients: 6 8 Number of Patients: 8 3 Number of Patients: 3 5 Number of Patients: 5  

Reported Stop Reasons

Why Patients Stopped Taking Dextromethorphan with Quinidine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 7   Did not seem to work: 54%
Side effects too severe 5   Side effects too severe: 38%
Expense 2   Expense: 15%
Course of treatment ended 2   Course of treatment ended: 15%

See all 13 patients who’ve stopped taking Dextromethorphan with Quinidine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Dextromethorphan with Quinidine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Dextromethorphan with Quinidine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Dextromethorphan with Quinidine

Always
 22 81%
Usually
 4 15%
Sometimes
 0 0%
Never
 1 4%

Burden

Difficulty being on treatment

Burden of Dextromethorphan with Quinidine

Very
 0 0%
Somewhat
 0 0%
A little
 4 15%
Not at all
 23 85%

Cost

Paid out of pocket

Cost of Dextromethorphan with Quinidine

$200+
 1 6%
$100-199
 0 0%
$50-99
 3 19%
$25-49
 7 44%
< $25
 5 31%

Sort by: Helpfulness | Most Recent

9 patient evaluations for Dextromethorphan with Quinidine

Purposes: ALS (Amyotrophic Lateral Sclerosis), Emotional lability, and emotions, to stop uncontrollable laughing and crying (Started Jun 06, 2012)
Date Dosage ALS (Amyotrophic Lateral Sclerosis) Perceived effectiveness Emotional lability Perceived effectiveness emotions, to stop uncontrollable laughing and crying Perceived effectiveness Side Effects Adherence Burden
Mar 24, 2013 20 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_default Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_default NoneNoneNoneNone AlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at all
Nov 12, 2012 20 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_default Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_default NoneNoneNoneNone AlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at all
Jun 20, 2012 20 mg Daily Led_efficacy_2Led_efficacy_2Led_defaultLed_default Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4 Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4 NoneNoneNoneNone AlwaysAlwaysAlwaysAlways A littleA littleA littleA little
Jun 08, 2012 20 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_default Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4 Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4 MildMildMildMild AlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at all
Date
Mar 24, 2013
Advice & Tips
Stopped only because I stated Emsam (Segeline) which can interact with Dextromathorphan.
Cost
$25-49 monthly
Date
Nov 12, 2012
Advice & Tips
After 5 months of taking Nudexta my ability to swallow has hardly declined at all. My speech, however, has continued to decline and is now all but gone.
Cost
$25-49 monthly
Date
Jun 20, 2012
Advice & Tips
Nudexta has seemed to almost completely 'cure' my emotional lability issues. My swallowing improvements remain so far.
Cost
$25-49 monthly
Date
Jun 08, 2012
Advice & Tips
I am feeling pretty good about Nudexta. Today is the second day is a row that the paper towel I use when I drink my morning coffee was relatively 'dry'. Usually it is sopping wet with coffee by the time I finish the cup, mostly because I gag a few times and lose a whole mouthful of coffee. Today I drank it without gaging once. It seemed as thought it took me about half the time to drink it also but I have not been timing myself.
Cost
$25-49 monthly
  • Icon_thumb_off 0 helpful marks
Purpose: Emotional lability (Started Apr 20, 2010)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Jan 31, 2013 20 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Date
Jan 31, 2013
Advice & Tips
Helps with swallowing Side effects when I went off one time. I suggest weaning off if stopping
  • Icon_thumb_off 0 helpful marks
Purpose: Emotional lability (Started May 07, 2012)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Jul 02, 2012 40 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major ModerateModerateModerateModerateModerate UsuallyUsuallyUsuallyUsuallyUsually Not at allNot at allNot at allNot at allNot at all
May 25, 2012 40 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate NoneNoneNoneNoneNone UsuallyUsuallyUsuallyUsuallyUsually Not at allNot at allNot at allNot at allNot at all
Date
May 25, 2012
Advice & Tips
Improved unwanted laughter, drooling and speech
Cost
$50-99 monthly
  • Icon_thumb_on 1 helpful mark
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