Glatiramer acetate Treatment Report

Category: Prescription Drugs

Most Popular Types: Copaxone

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What is Glatiramer acetate?

An example of Glatiramer acetate

Glatiramer acetate combines four amino acids including L-alanine, L-glutamic acid, L-lysine and L-tyrosine. It is used for Relapsing-Remitting Multiple Sclerosis (RRMS) to reduce the frequency and severity of relapses. It is administered as a subcutaneous injection.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
4,559 1,551 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
64 28 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
35 5 Efficacy_major Efficacy_moderate Efficacy_none Efficacy_cant_tell
26 11 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
10 1 Efficacy_cant_tell
8 1 Efficacy_slight

See all 3,641 patients currently taking Glatiramer acetate

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Reported Side Effects

Side effects as an overall problem

Severe
182
Moderate
282
Mild
717
None
430

Commonly reported side effects, conditions, and hospitalizations associated with Glatiramer acetate

370
293
273
265
241
160
See all 320 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Glatiramer acetate. See all 49 dosages

  daily 1 mg daily 1 mL daily 20 mg weekly 20 mg m,w,f 20 mg every other day 10 mg daily 20 mg daily 40 mg daily 200 mg daily
  210 Number of Patients: 210 39 Number of Patients: 39 9 Number of Patients: 9 8 Number of Patients: 8 8 Number of Patients: 8 149 Number of Patients: 149 13 Number of Patients: 13 3,107 Number of Patients: 3,107 12 Number of Patients: 12 8 Number of Patients: 8  

Reported Stop Reasons

Why Patients Stopped Taking Glatiramer acetate (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 764   Did not seem to work: 40%
Side effects too severe 601   Side effects too severe: 31%
Doctor's advice 554   Doctor's advice: 29%
Other 382   Other: 20%
Expense 139   Expense: 7%
Personal research 110   Personal research: 6%
Change in health plan coverage 57   Change in health plan coverage: 3%
Course of treatment ended 32   Course of treatment ended: 2%
Not indicated 29   Not indicated: 2%

See all 1824 patients who’ve stopped taking Glatiramer acetate

Currently Taking Glatiramer acetate

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Glatiramer acetate

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Glatiramer acetate

Always
1,209 75%
Usually
323 20%
Sometimes
46 3%
Never
33 2%

Burden

Difficulty being on treatment

Burden of Glatiramer acetate

Very
170 11%
Somewhat
358 22%
A little
561 35%
Not at all
522 32%

Cost

Paid out of pocket

Cost of Glatiramer acetate

$200+
142 12%
$100-199
71 6%
$50-99
132 11%
$25-49
307 25%
< $25
557 46%

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238 patient evaluations for Glatiramer acetate

  • sunset15
    Sex: F
    Data Quality: 2 stars
    MS: 7 yrs
    Type: Relapsing-Remitting
    Relapse: Moderate
    Sensation: Mild
    Overall: Mild
    Cognition: moderate
    Vision: none
    Speech: none
    Swallowing: none
    Upper limb: moderate
    Walking: moderate
  • 7890-thumb
  • See sunset15's full Glatiramer acetate history
Purposes: MS (Multiple Sclerosis) and General health (Started Oct 15, 2008)
Date Dosage MS (Multiple Sclerosis) Perceived effectiveness General health Perceived effectiveness Side Effects Adherence Burden
May 24, 2012 20 mg Daily Led_efficacy_2Led_efficacy_2Led_defaultLed_defaultSlight Led_efficacy_2Led_efficacy_2Led_defaultLed_defaultSlight NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Feb 20, 2009 20 mg Daily ?Can't tell MildMildMildMildMild AlwaysAlwaysAlwaysAlwaysAlways SomewhatSomewhatSomewhatSomewhatSomewhat
Side effects:
Lumps and bumps, Itching (pruritus), Injection site itching, Injection site reaction, Redness, Bee sting sensation, Injection site pain
Date
May 24, 2012
Advice & Tips
Always took it at night so I would not forget and I always wrote down the time and day.
Cost
< $25 monthly
  • Icon_thumb_off 0 helpful marks
  • dschipman
    Sex: F
    Data Quality: 2 stars
    MS: 13 yrs
    Type: Relapsing-Remitting
    Relapse: Moderate
    Sensation: Mild
    Overall: Mild
    Cognition: moderate
    Vision: moderate
    Speech: mild
    Swallowing: mild
    Upper limb: mild
    Walking: moderate
  • 9019-thumb
  • See dschipman's full Glatiramer acetate history
Purpose: MS (Multiple Sclerosis) (Started May 18, 2012)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
May 18, 2012 20 mg Daily ?Can't tell ModerateModerateModerateModerateModerate AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Date
May 18, 2012
Advice & Tips
Heat the site first, then apply a cold compress after taking the shot.
Cost
$25-49 monthly
  • Icon_thumb_off 0 helpful marks
  • TinkFan
    Sex: F
    Data Quality: 2 stars
    MS: 12 yrs
    Type: Relapsing-Remitting
    Sensation: Moderate
    Overall: Mild
    Cognition: moderate
    Vision: moderate
    Speech: mild
    Swallowing: mild
    Upper limb: mild
    Walking: moderate
  • 12492-thumb
  • See TinkFan's full Glatiramer acetate history
Purpose: MS (Multiple Sclerosis) (Started Apr 28, 2009)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
May 17, 2012 20 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major ModerateModerateModerateModerateModerate AlwaysAlwaysAlwaysAlwaysAlways A littleA littleA littleA littleA little
Aug 11, 2011 20 mg Daily Led_efficacy_2Led_efficacy_2Led_defaultLed_defaultSlight MildMildMildMildMild AlwaysAlwaysAlwaysAlwaysAlways A littleA littleA littleA littleA little
Side effects:
Injection site itching, Injection site pain, Injection site reaction, Lumps and bumps
  • Icon_thumb_off 0 helpful marks
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What is glatiramer?

Glatiramer is a combination of four amino acids (proteins) that affect the immune system.

Glatiramer is used to treat multiple sclerosis (MS) and to prevent relapse of MS.

This medication will not cure MS, but it can make relapses occur less often.

Glatiramer may also be used for other purposes not listed in this medication guide.


Precautions

Do not use this medication if you are allergic to glatiramer or to mannitol.

Before using glatiramer, tell your doctor if you are allergic to any drugs, or if you have any other illness or if you take any other medicines. You may not be able to use glatiramer, or you may require a dosage adjustment or special monitoring during treatment.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether glatiramer passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using glatiramer.

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Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a glatiramer overdose are not known.

Use the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

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Side Effects

Some people receiving a glatiramer injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel anxious, warm, itchy, tingly, or have a pounding heartbeat, tightness in your throat, or trouble breathing during the injection. This type of reaction may occur even after you have been using glatiramer for several months.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • chest pain;
  • fast heart rate;
  • fever, chills, body aches, flu symptoms; or
  • severe pain where the injection is given.

Less serious side effects include:

  • redness, minor pain, swelling, irritation, or a hard lump where the injection was given;
  • warmth, redness, or tingly feeling under the skin;
  • weakness, dizziness;
  • white patches or sores inside your mouth or on your lips;
  • joint pain;
  • nausea, diarrhea;
  • muscle tension or stiffness;
  • runny nose;
  • changes in your menstrual periods; or
  • increased urge to urinate.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

There may be other drugs that can affect glatiramer. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Other Names

Copaxone and glatiramer

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Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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