What is felodipine?
Felodipine is in a class of drugs called calcium channel blockers. Felodipine relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.
Felodipine is used to treat hypertension (high blood pressure).
Felodipine may also be used for purposes other than those listed in this medication guide.
Before taking felodipine, tell your doctor if you have
- liver disease; or
- another disease of the heart or blood vessels such as sick sinus syndrome, aortic stenosis, heart failure, low blood pressure, or coronary artery disease.
You may not be able to take felodipine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Felodipine is in the FDA pregnancy category C. This means that it is not known whether felodipine will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.
It is not known whether felodipine passes into breast milk. Do not take felodipine without first talking to your doctor if you are breast-feeding a baby.
If you are over 65 years of age, you may be more likely to experience side effects from felodipine. Your doctor may prescribe a lower dose of this medication.
Grapefruit and grapefruit juice may interact with felodipine. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Follow any recommendations your doctor makes about diet or exercise.
Use caution when you stand or sit up from a lying position, especially if you wake up during the night. You may become dizzy when changing positions.
Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness or dizziness while taking felodipine.
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Seek emergency medical attention.
Symptoms of a felodipine overdose include dizziness, weakness, chest pain, shortness of breath, fainting, an unusually fast or slow heartbeat, coma, slurred speech, and confusion.
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.
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If you experience any of the following serious side effects, stop taking felodipine and contact your doctor immediately or seek emergency medical treatment:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- unusually fast or slow heartbeat;
- chest pain;
- severe dizziness or fainting;
- abnormal behavior or psychosis;
- jaundice (yellowing of the skin or eyes), or
- swelling of the legs, ankles, or face.
Other, less serious side effects may be more likely to occur. Continue to take felodipine and talk to your doctor if you experience
- fatigue or tiredness;
- insomnia or difficulty sleeping;
- swelling of your gums;
- nausea or diarrhea;
- increased or difficult urination;
- muscle or joint discomfort; or
- flushing (redness).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.
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Before taking felodipine, tell your doctor if you are taking any of the following drugs:
- another heart medication to treat the same or another condition;
- erythromycin (E-Mycin, E.E.S., Eryc, Ery-Tab, others);
- itraconazole (Sporanox) or ketoconazole (Nizoral);
- cimetidine (Tagamet, Tagamet HB);
- carbamazepine (Tegretol);
- phenytoin (Dilantin); or
- rifampin (Rifadin, Rimactane) or rifabutin (Mycobutin).
You may not be able to take felodipine, or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.
Drugs other than those listed here may also interact with felodipine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.
Plendil and felodipine
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