What is albuterol-ipratropium?
Albuterol and ipratropium are bronchodilators that relax muscles in the airways and increase air flow to the lungs.
The combination of albuterol and ipratropium inhalation is used to prevent bronchospasm in people with chronic obstructive pulmonary disease (COPD) who are also using other medicines to control their condition.
Albuterol and ipratropium inhalation may also be used for other purposes not listed in this medication guide.
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Precautions
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Instructions
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Side Effects
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Interactions
Precautions
Do not use the albuterol and ipratropium inhaler (Combivent) if you are allergic to soybeans, peanuts, or other food products that contain soya lecithin.
Before using this medication, tell your doctor if you have:
- heart disease, high blood pressure, or congestive heart failure;
- a seizure disorder such as epilepsy;
- diabetes;
- overactive thyroid;
- glaucoma;
- an enlarged prostate or problems with urination; or
- liver or kidney disease.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether albuterol and ipratropium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Avoid getting this medication in your eyes. If this does happen, rinse the eyes with water and seek medical attention.
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Instructions
Seek emergency medical attention if you think you have used too much of this medicine. An overdose of albuterol and ipratropium can be fatal. Overdose symptoms may include chest pain or heavy feeling, rapid or uneven heart rate, pain spreading to the arm or shoulder, nausea, sweating, weakness, or general ill feeling.
Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.
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Side Effects
Stop using this medication and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using albuterol and ipratropium and call your doctor at once if you have any of these serious side effects:
- bronchospasm (wheezing, chest tightness, trouble breathing), especially after starting a new canister of this medicine;
- chest pain and fast, pounding, or uneven heart beats;
- swelling of your ankles or feet;
- pain or burning with urination; or
- increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure).
Less serious side effects may include:
- headache, dizziness, nervousness;
- drowsiness or sleep problems (insomnia);
- cough, hoarseness, sore throat, runny or stuffy nose;
- dry mouth, unusual taste in your mouth;
- tremors, numbness or tingly feeling;
- nausea, vomiting, upset stomach, diarrhea, constipation; or
- blurred vision.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
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Interactions
Before using this medication, tell your doctor if you are taking any of the following medicines:
- atropine (Donnatal, and others);
- belladonna;
- clidinium (Quarzan);
- dicyclomine (Bentyl);
- glycopyrrolate (Robinul);
- hyoscyamine (Anaspaz, Cystospaz, Levsin, and others);
- mepenzolate (Cantil);
- methantheline (Provocholine);
- methscopolamine (Pamine), scopolamine (Transderm-Scop);
- propantheline (Pro-Banthine);
- a beta-blocker such as acebutolol (Sectral), atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor), or propranolol (Inderal);
- a stimulant, ADHD medication, diet pills, or over-the-counter cold or allergy medicines;
- a diuretic (water pill) such as furosemide (Lasix), bumetanide (Bumex), ethacrynic acid (Edecrin), torsemide (Demadex), hydrochlorothiazide (Hydrodiuril), chlorthalidone (Hygroton, Thalitone), or chlorothiazide (Diuril); or
- an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate).
This list is not complete and there may be other drugs that can interact with albuterol and ipratropium. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Other Names
Combivent, DuoNeb, albuterol-ipratropium, and ipratropium-albuterol
Available Strengths & Dosages
| Route |
Form |
Strength |
| inhalation |
aerosol with adapter |
90 mcg-18 mcg/inh |
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Disclaimer
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04
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