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What is Naltrexone?

Naltrexone, in low doses such as 3mg to 4.5mg, has been found to boost the immune system in MS, autoimmune diseases, and central nervous system disorders. Naltrexone was FDA-approved in 1985 for the management of alcohol dependence and opioid dependence at 50mg doses.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
MS (Multiple Sclerosis) 391 161 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Fibromyalgia 79 51 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Fatigue 74 42 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Other 42 16 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
ALS (Amyotrophic Lateral Sclerosis) 36 19 Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Pain 31 16 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell

See all 646 patients currently taking Naltrexone

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Reported Side Effects

Side effects as an overall problem

Severe
 20
Moderate
 28
Mild
 63
None
 215

Commonly reported side effects, conditions, and hospitalizations associated with Naltrexone

Vivid dreams 20
Nausea 11
Stiffness/Spasticity 10
Headaches 7
Stiffness in morning 7
Early morning wakefulness 6
See all 90 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Naltrexone. See all 53 dosages ►

  daily 1 mg daily 1.5 mg daily 2 mg daily 2.5 mg daily 3 mg daily 3.5 mg daily 4 mg daily 4.5 mg daily 50 mg daily
  7 Number of Patients: 7 17 Number of Patients: 17 29 Number of Patients: 29 14 Number of Patients: 14 8 Number of Patients: 8 154 Number of Patients: 154 24 Number of Patients: 24 33 Number of Patients: 33 306 Number of Patients: 306 16 Number of Patients: 16  

Reported Stop Reasons

Why Patients Stopped Taking Naltrexone (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 94   Did not seem to work: 50%
Other 49   Other: 26%
Side effects too severe 38   Side effects too severe: 20%
Doctor's advice 30   Doctor's advice: 16%
Expense 7   Expense: 4%
Personal research 6   Personal research: 3%
Course of treatment ended 6   Course of treatment ended: 3%
Not indicated 5   Not indicated: 3%
Change in health plan coverage 1   Change in health plan coverage: 1%

See all 184 patients who’ve stopped taking Naltrexone

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Naltrexone

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Naltrexone

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Naltrexone

Always
 279 86%
Usually
 37 11%
Sometimes
 4 1%
Never
 6 2%

Burden

Difficulty being on treatment

Burden of Naltrexone

Very
 5 2%
Somewhat
 17 5%
A little
 31 10%
Not at all
 273 84%

Cost

Paid out of pocket

Cost of Naltrexone

$200+
 0 0%
$100-199
 1 0%
$50-99
 37 13%
$25-49
 147 50%
< $25
 109 37%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 28, 2012.