What is chlordiazepoxide-clidinium?
Chlordiazepoxide is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Chlordiazepoxide affects chemicals in the brain that may become unbalanced and cause anxiety.
Clidinium reduces stomach acid and decreases intestinal spasms.
The combination of chlordiazepoxide and clidinium is used to treat stomach ulcers, irritable bowel syndrome, and intestinal infections.
Chlordiazepoxide and clidinium may also be used for other purposes not listed in this medication guide.
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Precautions
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Instructions
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Side Effects
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Interactions
Precautions
Do not use this medication if you are allergic to chlordiazepoxide or to other benzodiazepines, such as alprazolam (Xanax), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).
Do not take chlordiazepoxide and clidinium if you have:
- glaucoma;
- an enlarged prostate;
- a bladder obstruction; or
- problems with urination.
Before taking chlordiazepoxide and clidinium, tell your doctor if you are allergic to any drugs, or if you have:
- asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;
- myasthenia gravis;
- ulcerative colitis, or a blockage in your intestines;
- kidney or liver disease;
- a history of depression or suicidal thoughts or behavior; or
- a history of drug or alcohol addiction.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.
Chlordiazepoxide can cause birth defects in an unborn baby. Do not use chlordiazepoxide and clidinium without your doctor’s consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.
Chlordiazepoxide and clidinium may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
The sedative effects of chlordiazepoxide may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking chlordiazepoxide and clidinium.
Do not drink alcohol while taking chlordiazepoxide and clidinium. This medication can increase the effects of alcohol.
Chlordiazepoxide and clidinium can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid using other medicines that make you sleepy (especially cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety). They can add to the side effects of chlordiazepoxide and clidinium. Tell your doctor if you regularly use any of these medicines.
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Instructions
Seek emergency medical attention if you think you have used too much of this medicine. An overdose of chlordiazepoxide can be fatal.
Overdose symptoms may include extreme drowsiness, dry mouth, blurred vision, confusion, muscle weakness, slow or shallow breathing, feeling light-headed, or fainting.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
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Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- confusion;
- depressed mood, thoughts of suicide or hurting yourself;
- restless muscle movements in your eyes, tongue, jaw, or neck;
- hyperactivity, agitation, hostility;
- hallucinations;
- jaundice (yellowing of the skin or eyes); or
- urinating less than usual or not at all.
Less serious side effects may include:
- drowsiness, tiredness;
- swelling;
- skin rash;
- blurred vision;
- dry mouth;
- nausea, vomiting, constipation; or
- irregular menstrual periods.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
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Interactions
Before taking chlordiazepoxide and clidinium, tell your doctor if you are using any of the following drugs:
- a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Luminal, Solfoton);
- a blood thinner such as warfarin (Coumadin);
- an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate);
- medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), mesoridazine (Serentil), pimozide (Orap), or thioridazine (Mellaril);
- narcotic medications such as butorphanol (Stadol), codeine, hydrocodone (Lortab, Vicodin), levorphanol (Levo-Dromoran), meperidine (Demerol), methadone (Dolophine, Methadose), morphine (Kadian, MS Contin, Oramorph), naloxone (Narcan), oxycodone (OxyContin), propoxyphene (Darvon, Darvocet); or
- antidepressants such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), protriptyline (Vivactil), sertraline (Zoloft), or trimipramine (Surmontil).
This list is not complete and there may be other drugs that can interact with chlordiazepoxide and clidinium. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Other Names
Chlordinium, Clindex, Librax, chlordiazepoxide-clidinium, and clidinium-chlordiazepoxide
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Disclaimer
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04
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