Axert Treatment Report

Category: Prescription Drugs

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Generic Name: Almotriptan

What is Axert?

An example of Axert

This is an antimigraine agent used for acute treatment of migraine with or without aura. It causes vasoconstriction and reduces sterile inflammation associated with antidromic neuronal transmission correlating with relief of migraine.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
22 6 Efficacy_major Efficacy_moderate Efficacy_none
16 3 Efficacy_major Efficacy_moderate Efficacy_slight
3 2 Efficacy_moderate Efficacy_cant_tell
1 0
1 0

See all 21 patients currently taking Axert

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Reported Side Effects

Side effects as an overall problem

Severe
0
Moderate
0
Mild
3
None
8

Commonly reported side effects, conditions, and hospitalizations associated with Axert

1
1
1

Reported Dosages

  12.5 mg as needed 6.25mg as needed 2 12.5mg as needed 2 6.25mg as needed as needed 12.5mg as needed 6.25 mg daily 10 mg daily 12.5 mg daily
  1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 12 Number of Patients: 12 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2  

Reported Stop Reasons

Why Patients Stopped Taking Axert (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 12   Did not seem to work: 57%
Expense 3   Expense: 14%
Change in health plan coverage 3   Change in health plan coverage: 14%
Other 2   Other: 10%
Doctor's advice 1   Doctor's advice: 5%

See all 18 patients who’ve stopped taking Axert

Currently Taking Axert

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0
0
0

Stopped Taking Axert

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Axert

Always
7 64%
Usually
1 9%
Sometimes
2 18%
Never
1 9%

Burden

Difficulty being on treatment

Burden of Axert

Very
1 9%
Somewhat
0 0%
A little
1 9%
Not at all
9 82%

Cost

Paid out of pocket

Cost of Axert

$200+
0 0%
$100-199
2 40%
$50-99
0 0%
$25-49
0 0%
< $25
3 60%

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3 patient evaluations for Axert

Purpose: Migraine (Started Aug 01, 2005)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Jun 05, 2011   Led_efficacy_1Led_defaultLed_defaultLed_defaultNone NoneNoneNoneNoneNone NeverNeverNeverNeverNever Not at allNot at allNot at allNot at allNot at all
Date
Jun 05, 2011
Advice & Tips
didnt work for me (no triptans did except relpax and it only worked rarely)
Cost
< $25 monthly
  • Icon_thumb_off 0 helpful marks
  • Impy Ann1
    Sex: F
    Data Quality: 0 stars
    MS: 32 yrs
    Type: Relapsing-Remitting
    Sensation: Moderate
    Overall: Mild
    Cognition: mild
    Vision: mild
    Speech: mild
    Swallowing: mild
    Upper limb: mild
    Walking: moderate
  • 7119-thumb
  • See Impy Ann1's full Axert history
Purpose: Migraine headaches (Started Sep 01, 2008)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Dec 01, 2008 As needed Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways VeryVeryVeryVeryVery
Date
Dec 01, 2008
Advice & Tips
Find and use a migraine preventative as this is an expensive medication and should be used only when necessary.
Cost
$100-199 monthly
  • Icon_thumb_off 0 helpful marks
Purpose: Migraine (Started Jan 01, 2004)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Jul 01, 2006 As needed Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks

8 additional evaluations for Axert are not currently shared publicly.

What is almotriptan?

Almotriptan is a headache medicine. It is believed to work by narrowing the blood vessels around the brain. Almotriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Almotriptan is used to treat migraine headaches.

Almotriptan will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

Almotriptan should not be used to treat common tension headaches or any headache that seems to be different from your ususal migraine headaches. Use this medication only if your condition has been confirmed by a doctor as migraine headaches.

Almotriptan may also be used for purposes other than those listed in this medication guide.


Precautions

You should not use this medication if you are allergic to almotriptan, or if you have:

  • a history of heart disease, angina (chest pain), blood circulation problems, heart attack, or stroke, including "mini-stroke";
  • severe or uncontrolled high blood pressure; or
  • a headache that is not like other headaches you have had.

If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before taking almotriptan, tell your doctor if you have:

  • liver disease;
  • kidney disease;
  • ischemic bowel disease;
  • heart disease, high blood pressure, a heart rhythm disorder;
  • coronary artery disease (or risk factors that include diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).

FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Before taking almotriptan, tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether almotriptan passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medicine to anyone under 18 years old.

Do not take almotriptan within 24 hours before or after using another migraine headache medicine, including:

  • eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), sumatriptan (Imitrex, Treximet), or zolmitriptan (Zomig); or
  • ergot medicine such as dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), ergonovine (Ergotrate), methylergonovine (Methergine), or methysergide (Sansert).

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Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose could cause high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, or seizure).

Since almotriptan is used as needed, it does not have a daily dosing schedule. Call your doctor promptly if your symptoms do not improve after using almotriptan.

After taking a almotriptan tablet, you must wait two (2) hours before taking a second tablet. Do not take more than two (2) almotriptan tablets in 24 hours.

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Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using almotriptan and call your doctor at once if you have any of these serious side effects:

  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
  • sudden numbness or weakness, especially on one side of the body;
  • sudden headache, confusion, problems with vision, speech, or balance;
  • sudden and severe stomach pain and bloody diarrhea;
  • numbness or tingling and a pale or blue-colored appearance in your fingers or toes; or
  • (if you are also taking an antidepressant) - agitation, high fever, sweating, fast or pounding heartbeats, nausea, vomiting, diarrhea, loss of balance or coordination, overactive reflexes, hallucinations, fainting.

Less serious side effects may include:

  • mild headache (not a migraine);
  • dry mouth, mild nausea;
  • feeling of pain or tightness in your jaw, neck, or throat;
  • pressure or heavy feeling in any part of your body;
  • dizziness, drowsiness, weakness; or
  • mild tingly feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

Before taking almotriptan, tell your doctor if you are using any of the following drugs:

  • diclofenac (Arthrotec, Cataflam, Voltaren, Flector Patch, Solareze);
  • isoniazid (for treating tuberculosis);
  • an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), o venlafaxine (Effexor);
  • an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), or erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin);
  • an antifungal medication such as itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend);
  • heart or blood pressure medication such as diltiazem (Cardizem, Dilacor, Tiazac), nicardipine (Cardene), quinidine (Quinaglute, Quinidex, Quin-Release), or verapamil (Calan, Covera, Isoptin, Verelan); or
  • HIV/AIDS medicine such as amprenavir (Agenerase), atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase, Fortovase), or ritonavir (Norvir).

This list is not complete and there may be other drugs that can interact with almotriptan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Other Names

Axert and almotriptan

Available Strengths & Dosages


Route Form Strength
oral tablet 6.25 mg
oral tablet 12.5 mg

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Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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