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What is Alendronate?

Alendronate is a bisphosphonate that is used to treat and prevent osteoporosis due to menopause, low bone mineral density or induced by glucocorticoid therapy; for Paget's disease of the bone in patients who are symptomatic, at risk for future complications or with elevated alkaline phosphatase.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Osteoporosis 98 19 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Osteopenia 47 12 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Other 27 9 Efficacy_major Efficacy_none Efficacy_cant_tell
General health 15 3 Efficacy_moderate Efficacy_cant_tell
Bone loss preventative 6 1 Efficacy_cant_tell
Treat side effects of another treatment 5 1 Efficacy_none

See all 163 patients currently taking Alendronate

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Reported Side Effects

Side effects as an overall problem

Severe
7
Moderate
4
Mild
3
None
35

Reported Dosages

Frequently reported dosages based on patients currently taking Alendronate. See all 25 dosages

  70mg as needed weekly 10 mg weekly 70 mg monthly 35 mg weekly 70 mg every other week 70 mg weekly 70 mg/75 mL weekly 40 mg daily 70 mg/75 mL daily
  2 Number of Patients: 2 2 Number of Patients: 2 4 Number of Patients: 4 2 Number of Patients: 2 8 Number of Patients: 8 3 Number of Patients: 3 80 Number of Patients: 80 45 Number of Patients: 45 2 Number of Patients: 2 3 Number of Patients: 3  

Reported Stop Reasons

Why Patients Stopped Taking Alendronate (multiple reasons could be selected)
Reason # Patients Percentage of patients
Doctor's advice 26   Doctor's advice: 38%
Side effects too severe 20   Side effects too severe: 29%
Other 14   Other: 20%
Personal research 13   Personal research: 19%
Did not seem to work 4   Did not seem to work: 6%
Course of treatment ended 2   Course of treatment ended: 3%
Change in health plan coverage 2   Change in health plan coverage: 3%
Not indicated 1   Not indicated: 1%

See all 66 patients who’ve stopped taking Alendronate

Currently Taking Alendronate

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Alendronate

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Alendronate

Always
32 65%
Usually
12 24%
Sometimes
2 4%
Never
3 6%

Burden

Difficulty being on treatment

Burden of Alendronate

Very
4 8%
Somewhat
13 27%
A little
12 24%
Not at all
20 41%

Cost

Paid out of pocket

Cost of Alendronate

$200+
1 3%
$100-199
1 3%
$50-99
1 3%
$25-49
2 6%
< $25
26 84%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 28, 2012.