What is atovaquone?
Atovaquone is a medication that interferes with the reproduction of protozoa (single-cell organisms) that can cause disease in the body.
Atovaquone is used to treat or prevent pneumonia caused by a fungal infection called Pneumocystitis carinii (also called Pneumocystis jiroveci).
Atovaquone may also be used for other purposes not listed in this medication guide.
You should not use this medication if you are allergic to atovaquone.
If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before you take atovaquone, tell your doctor if you have:
- liver disease; or
- a stomach or intestinal disorder.
FDA pregnancy category C. It is not known whether atovaquone is harmful to an unborn baby. Before you take atovaquone, tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether atovaquone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using this medication.
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Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of an atovaquone overdose are not known.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- easy bruising or bleeding, unusual weakness;
- fever, flu symptoms;
- white patches in your mouth or throat;
- worsening cough;
- bronchospasm (wheezing, chest tightness, trouble breathing);
- fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
- nausea, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
- mild nausea, vomiting, stomach pain or upset,
- diarrhea, constipation;
- weakness, dizziness;
- muscle pain;
- mild skin rash;
- sweating; or
- sleep problems (insomnia).
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
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Tell your doctor about all other medications you are using, especially:
- carbamazepine (Carbatrol, Tegretol);
- clozapine (Clozaril, FazaClo);
- rifabutin (Mycobutin); or
- rifampin (Rifadin, Rifater, Rifamate, Rimactane).
This list is not complete and there may be other drugs that can interact with atovaquone. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Mepron and atovaquone
Available Strengths & Dosages
||750 mg/5 mL
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