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Brand Names: Sirdalud Retard, Zanaflex

What is Tizanidine? Tizanidine is a centrally acting alpha2-adrenergic agonist. It is a skeletal muscle relaxant used for treatment of muscle spasticity. Off label it is used for tension headaches, low back pain, and trigeminal neuralgia.

See more information, including instructions, precautions, side effects, and interactions.


Dosages

Based on the patients currently taking Tizanidine.

Top 10 (Show all)

All (Show Top 10)

  0 mg day 0 mg none 1 mg day 2 mg none 2 mg day 2.5 mg day 3 mg day 3 day 4 mg none 4 mg day 5 mg day 6 mg day 8 mg day 10 mg day 12 mg day 14 mg day 16 mg day 18 mg day 20 mg day 24 mg day 28 mg day 30 mg day 32 mg day 40 mg day 50 mg day 100 mg day 300 mg day
  41 Number of Patients: 41 15 Number of Patients: 15 1 Number of Patients: 1 1 Number of Patients: 1 28 Number of Patients: 28 1 Number of Patients: 1 3 Number of Patients: 3 1 Number of Patients: 1 3 Number of Patients: 3 98 Number of Patients: 98 6 Number of Patients: 6 20 Number of Patients: 20 49 Number of Patients: 49 8 Number of Patients: 8 26 Number of Patients: 26 2 Number of Patients: 2 26 Number of Patients: 26 6 Number of Patients: 6 10 Number of Patients: 10 17 Number of Patients: 17 2 Number of Patients: 2 4 Number of Patients: 4 5 Number of Patients: 5 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2 2 Number of Patients: 2  

Duration

How long current patients have been taking Tizanidine or how long patients were taking Tizanidine before stopping.

Currently taking Tizanidine

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
4
15
28
40
60
105

Stopped taking Tizanidine

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
9
13
17
6
4
13
Why Patients Stopped Taking Tizanidine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 28 44% Did not seem to work: 44%
Side effects too severe 14 22% Side effects too severe: 22%
Doctor's advice 11 17% Doctor's advice: 17%
Other 8 13% Other: 13%
Personal research 6 10% Personal research: 10%
Expense 6 10% Expense: 10%
Course of treatment ended 2 3% Course of treatment ended: 3%
Not indicated 1 2% Not indicated: 2%

Patient Reported Evaluations

Results from 36 patient evaluations. See the overall results and all individual evaluations.

Efficacy (Effect based on reason taken)

Major 39% 11
Moderate 29% 8
Slight 25% 7
None 7% 2

Stiffness/spasticity

Side-effects (as an overall problem)

Severe 8% 3
Moderate 31% 11
Mild 31% 11
None 31% 11

Top reported side-effects include: sleepy, Fatigue, makes me very sleepy

Summary results are based on 36 individual responses. For more information, see overall results for Adherence, Burden and Cost.

Individual Patient Reported Evaluations (2 of 36)

  • feathers4me
    Sensation: Severe
    Overall: Moderate
    Cognition: moderate
    Vision: moderate
    Speech: mild
    Swallowing: mild
    Upper limb: moderate
    Walking: severe
  • feathers4me
  • by feathers4me
    Aug 18, 2008
  • EfficacyMajor
  • Side-effectsModerate
  • Stiffness/spasticity

  • jntdsn
    Mouth/throat: none
    Arms: mild
    Chest: mild
    Legs: mild
  • jntdsn
  • by jntdsn
    Aug 18, 2008
  • EfficacyMajor
  • Side-effectsModerate
  • Stiffness/spasticity

See all evaluation results for Tizanidine



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