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Brand Names:
Sirdalud Retard, Zanaflex
What is Tizanidine? Tizanidine is a centrally acting alpha2-adrenergic agonist. It is a skeletal muscle relaxant used for treatment of muscle spasticity. Off label it is used for tension headaches, low back pain, and trigeminal neuralgia.
See more information, including instructions, precautions, side effects, and interactions.
438 patients in the community are taking or have taken Tizanidine.
| Reason | # Patients | Percentage of patients |
|---|---|---|
| Stiffness/spasticity | 294 | 67% |
| Other | 47 | 10% |
| Pain | 18 | 4% |
| disease-related symptoms | 14 | 3% |
| Muscle Spasms, feet and toes | 5 | 1% |
| Spasms | 4 | <1% |
| Muscle spasms, neck and shoulders | 4 | <1% |
| General health | 3 | <1% |
| Slow my MS progress | 3 | <1% |
| Fasciculations | 3 | <1% |
| Support another treatment | 2 | <1% |
| Insomnia | 2 | <1% |
| Depression | 2 | <1% |
| MS Hug, or girdle-band sensation, stomach/chest/thighs | 1 | <1% |
| Burning sensation, soles of feet | 1 | <1% |
| Headaches/ Migraines | 1 | <1% |
| Muscle twitching (fasciculations) | 1 | <1% |
| Muscle cramping, spasms | 1 | <1% |
| Night-time leg spasms | 1 | <1% |
| Fatigue | 1 | <1% |
| Pain, leg | 1 | <1% |
| twitches and jerks | 1 | <1% |
| Sexual dysfunction | 1 | <1% |
| Calf, feet cramps and muscle spasms | 1 | <1% |
| Cramps, calf muscles | 1 | <1% |
| tonic spasm | 1 | <1% |
| Spasms, calves | 1 | <1% |
| Don't know | 1 | <1% |
| Mobility | 1 | <1% |
| Treat Parkinson's | 1 | <1% |
| Muscle tension | 1 | <1% |
| 0 mg day | 0 mg none | 1 mg day | 2 mg none | 2 mg day | 2.5 mg day | 3 mg day | 3 day | 4 mg none | 4 mg day | 5 mg day | 6 mg day | 8 mg day | 10 mg day | 12 mg day | 14 mg day | 16 mg day | 18 mg day | 20 mg day | 24 mg day | 28 mg day | 30 mg day | 32 mg day | 40 mg day | 50 mg day | 100 mg day | 300 mg day | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
41
|
15
|
1
|
1
|
28
|
1
|
3
|
1
|
3
|
98
|
6
|
20
|
49
|
8
|
26
|
2
|
26
|
6
|
10
|
17
|
2
|
4
|
5
|
1
|
1
|
2
|
2
|
||
How long current patients have been taking Tizanidine or how long patients were taking Tizanidine before stopping.
Results from 36 patient evaluations. See the overall results and all individual evaluations.
| Major | 39% | 11 |
|---|---|---|
| Moderate | 29% | 8 |
| Slight | 25% | 7 |
| None | 7% | 2 |
Stiffness/spasticity
| Severe | 8% | 3 |
|---|---|---|
| Moderate | 31% | 11 |
| Mild | 31% | 11 |
| None | 31% | 11 |
Top reported side-effects include: sleepy, Fatigue, makes me very sleepy
Summary results are based on 36 individual responses. For more information, see overall results for Adherence, Burden and Cost.