Because colchicine was developed prior to federal regulations requiring FDA review of all marketed drug products, the uses for colchicine have not been approved by the FDA. Newer drugs have been developed and FDA-approved to treat the conditions that colchicine is used to treat.
You should not use this medication if you are allergic to colchicine, or if you have heart disease, kidney disease, or a severe gastrointestinal disorder.
Before taking colchicine, tell your doctor if you have a stomach ulcer, ulcerative colitis, Crohn’s disease, or intestinal bleeding or other disorder.
To treat a gout attack, for best results take colchicine at the first sign of the attack. The longer you wait to start taking the medication, the less effective it may be.
If you use this medication over a long period of time, your blood may need to be tested on a regular basis. Do not miss any scheduled appointments.
Call your doctor at once if you have a serious side effect such as severe vomiting or diarrhea, easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms, numbness, burning, pain, or tingly feeling, blood in your urine, or urinating less than usual or not at all.