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What is Mesalamine?

Mesalamine, a derivative of 5-aminosalicylic acid, is an anti-inflammatory agent. Orally it is used to treat and maintain remission of mild to moderate ulcerative colitis. Rectal administration is used to treat active mild-to-moderate distal ulcerative colitis, proctosigmoiditis, or proctitis.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Ulcerative colitis 66 25 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Crohn's Disease 60 11 Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Ulcerative colitis 12 5 Efficacy_major Efficacy_moderate Efficacy_slight
Other 9 2 Efficacy_none Efficacy_cant_tell
Crohn's disease and Colitis 5 0
Colitis 5 2 Efficacy_major

See all 129 patients currently taking Mesalamine

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Reported Side Effects

Side effects as an overall problem

Severe
 1
Moderate
 7
Mild
 8
None
 31

Commonly reported side effects, conditions, and hospitalizations associated with Mesalamine

Hair loss 5
Diarrhea 2
None 2
Abdominal bloating 1
Stomach pain 1
Abdominal pain 1
See all 11 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Mesalamine. See all 35 dosages ►

  4g/60mL as needed 2.4 g daily 4 g daily 4.8 g daily 800 mg daily 1,000 mg daily 2,400 mg daily 3,000 mg daily 3,200 mg daily 4,000 mg daily
  4 Number of Patients: 4 11 Number of Patients: 11 4 Number of Patients: 4 13 Number of Patients: 13 7 Number of Patients: 7 7 Number of Patients: 7 21 Number of Patients: 21 10 Number of Patients: 10 4 Number of Patients: 4 11 Number of Patients: 11  

Reported Stop Reasons

Why Patients Stopped Taking Mesalamine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 20   Did not seem to work: 43%
Doctor's advice 14   Doctor's advice: 30%
Side effects too severe 11   Side effects too severe: 23%
Other 7   Other: 15%
Course of treatment ended 5   Course of treatment ended: 11%
Personal research 3   Personal research: 6%
Expense 2   Expense: 4%
Change in health plan coverage 2   Change in health plan coverage: 4%
Not indicated 2   Not indicated: 4%

See all 44 patients who’ve stopped taking Mesalamine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Mesalamine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Mesalamine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Mesalamine

Always
 30 64%
Usually
 13 28%
Sometimes
 3 6%
Never
 1 2%

Burden

Difficulty being on treatment

Burden of Mesalamine

Very
 3 6%
Somewhat
 11 23%
A little
 14 30%
Not at all
 19 40%

Cost

Paid out of pocket

Cost of Mesalamine

$200+
 1 4%
$100-199
 2 8%
$50-99
 1 4%
$25-49
 3 12%
< $25
 18 72%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 28, 2012.