Omeprazole-sodium bicarbonate is a proton pump inhibitor used for short term treatment of ulcer disease; for heartburn and other symptoms of gastroesophageal reflux disease; for healing of erosive esophagitis.
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What is omeprazole-sodium bicarbonate?
Omeprazole decreases the amount of acid your stomach produces. Sodium bicarbonate is an antacid that raises the pH in your stomach to keep the omeprazole from breaking down in stomach acid.
Omeprazole and sodium bicarbonate is used to treat ulcers, gastroesophageal reflux disease (GERD), and other conditions involving excessive stomach acid production.
Omeprazole and sodium bicarbonate may also be used for other purposes not listed in this medication guide.
This medication contains sodium bicarbonate, a form of salt. Each capsule contains the equivalent of 300 mg of sodium. Each packet of powder contains the equivalent of 460 mg of sodium. If you are on a low-salt or low-sodium diet, you may not be able to use omeprazole and sodium bicarbonate. Talk with your doctor.
Before using this medication, tell your doctor if you have any of the following conditions:
metabolic or respiratory alkalosis (usually after prolonged illness); or
low calcium or potassium levels in your blood.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Omeprazole can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using omeprazole and sodium bicarbonate.
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include confusion, drowsiness, blurred vision, fast heartbeat, sweating, dry mouth, nausea or vomiting.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
easy bruising or bleeding, unusual weakness; or
fast, slow, or uneven heartbeat.
Less serious side effects may include:
nausea, stomach pain; or
diarrhea or constipation;
white patches or sores inside your mouth or on your lips;
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medicines you use, especially:
cyclosporine (Neoral, Sandimmune, Gengraf);
diazepam (Valium) or similar sedatives;
tacrolimus (Prograf); or
This list is not complete and there may be other drugs that can interact with omeprazole and sodium bicarbonate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Zegerid, omeprazole-sodium bicarbonate, and sodium bicarbonate-omeprazole
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