What is letrozole?
Letrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.
Letrozole is used to treat breast cancer in postmenopausal women. It is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years.
Letrozole may also be used for purposes other than those listed here.
You should not use this medication if you are allergic to letrozole, or if you have not gone completely through menopause.
Before taking letrozole, tell your doctor if you have liver disease. You may need a dose adjustment or special tests to safely take this medication.
FDA pregnancy category D: This medication can cause harm to an unborn baby. Do not use letrozole if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.
It is not known whether letrozole passes into breast milk. Do not take letrozole if you are breast-feeding a baby.
Letrozole can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
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Seek emergency medical attention if you think you have used too much of this medicine.
An overdose of letrozole is not expected to produce life-threatening symptoms.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
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Stop using letrozole and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
- hot flashes, warmth or redness in your face or chest;
- headache, muscle or joint pain;
- night sweats;
- weight gain;
- fatigue, feeling weak;
- nausea; or
- swelling in your hands, ankles, or feet.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
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There may be other drugs that can affect letrozole. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Femara and letrozole
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