Do not this medication if you are allergic to temozolomide or to another cancer medication called dacarbazine (DTIC-Dome). Before taking temozolomide, tell your doctor if you have liver or kidney disease.
Do not use this medication without telling your doctor if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.
Do not open the temozolomide capsule, or use a capsule that has been accidentally broken. The powder inside the capsule can be dangerous if you accidentally inhale it or if it gets in your eyes, mouth, or nose, or on your skin. If you must handle a broken capsule, ask your doctor or pharmacist how to safely handle and dispose of it. Rinse off any medicine that gets on your skin or in your eyes, nose, or mouth.
Temozolomide is often given together with radiation treatment, and then continued for several weeks or months after radiation treatment ends. There may be periods of time when you will take temozolomide for only a few days in a row and then wait another 2 to 4 weeks before you start a new treatment cycle and take it again. Follow your doctor’s instructions carefully.
Your doctor may occasionally change your dose to make sure you get the best results from this medication. The size, color, and number of temozolomide capsules you take may be different from time to time as your doctor adjusts your dose. Be sure you know the correct number of capsules to take and on which days to take them. Contact your doctor or pharmacist if you have any questions.
Taking temozolomide may increase your risk of developing certain types of bone marrow cancer. Talk with your doctor about your individual risk.