What is pantoprazole?
Pantoprazole is in a group of drugs called proton pump inhibitors. It decreases the amount of acid produced in the stomach.
Pantoprazole is used to treat erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excess stomach acid such as Zollinger-Ellison syndrome.
Pantoprazole may also be used for purposes other than those listed in this medication guide.
Do not take this medication if you are allergic to pantoprazole. Before taking pantoprazole, tell your doctor if you are allergic to any drugs.
Some conditions must be treated long-term with pantoprazole. The chronic use of pantoprazole has caused stomach cancer in animal studies, but it is not known if this medication would have the same effects in humans. Talk with your doctor about your specific risk of developing stomach cancer.
Long-term treatment with pantoprazole may also make it harder for your body to absorb vitamin B-12, resulting in a deficiency of this vitamin. Symptoms of a vitamin B-12 deficiency may develop slowly and include pale skin, weakness, tired feeling, shortness of breath, and a fast heart rate. Talk with your doctor if you need long-term pantoprazole treatment and you have concerns about vitamin B-12 deficiency.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether pantoprazole passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using pantoprazole.
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Seek emergency medical attention if you think you have used too much of this medicine. An overdose of pantoprazole is not expected to produce life-threatening symptoms.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects are more likely to occur, such as:
- nausea, vomiting;
- gas, stomach pain;
- diarrhea; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.
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Before taking pantoprazole, tell your doctor if you are using any of the following drugs:
- ampicillin (Omnipen, Principen);
- atazanavir (Reyataz);
- a blood thinner such as warfarin (Coumadin);
- clopidogrel (Plavix);
- ketoconazole (Nizoral); or
- iron (Feosol, Mol-Iron, Fergon, Femiron, others).
This list is not complete and there may be other drugs that can interact with pantoprazole. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Protonix, Protonix IV, and pantoprazole
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