Clorazepate is a benzodiazepine-type used for the treatment of generalized anxiety disorder; for the management of alcohol withdrawal; and as an adjunct anticonvulsant for the management of partial seizures.
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What is clorazepate?
Clorazepate is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Clorazepate affects chemicals in the brain that may become unbalanced and cause anxiety or seizures.
Clorazepate is used to treat anxiety disorders, partial seizures, or alcohol withdrawal symptoms.
Clorazepate may also be used for other purposes not listed in this medication guide.
Do not use this medication if you have narrow-angle glaucoma, or if you are allergic to clorazepate or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).
Before taking clorazepate, tell your doctor if you are allergic to any drugs, or if you have:
asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;
kidney or liver disease;
epilepsy or other seizure disorder;
a history of depression or suicidal thoughts or behavior; or
a history of drug or alcohol addiction.
If you have any of these conditions, you may need a dose adjustment or special tests during treatment.
Clorazepate can cause birth defects in an unborn baby. Do not use clorazepate without your doctor’s consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.
Clorazepate can pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
The sedative effects of clorazepate may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking clorazepate.
Do not give this medication to a child younger than 9 years old.
Do not drink alcohol while taking clorazepate. This medication can increase the effects of alcohol.
Clorazepate can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by clorazepate.
Seek emergency medical attention if you think you have used too much of this medicine. An overdose of clorazepate can be fatal.
Overdose symptoms may include extreme drowsiness, feeling light-headed, fainting, or coma.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
This list is not complete and there may be other drugs that can interact with clorazepate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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