Esomeprazole Treatment Report

Category: Prescription Drugs

Most Popular Types: Nexium, Neopral, Nexium IV

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See also: Esomeprazole-naproxen, Vimovo

What is Esomeprazole?

An example of Esomeprazole

Esomeprazole is a proton pump inhibitor. It is used for treatment of gastrointestinal reflux disease; for duodenal and gastric ulcers; and for conditions associated with hypersecretion of gastric acid, including Zollinger-Ellison syndrome.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
322 74 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
293 43 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
24 5 Efficacy_major Efficacy_moderate Efficacy_slight
19 1 Efficacy_slight
17 4 Efficacy_major Efficacy_moderate Efficacy_cant_tell
16 2 Efficacy_major Efficacy_none

See all 722 patients currently taking Esomeprazole

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Reported Side Effects

Side effects as an overall problem

Severe
2
Moderate
3
Mild
16
None
123

Commonly reported side effects, conditions, and hospitalizations associated with Esomeprazole

2
1
1
1
1
1
See all 13 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Esomeprazole. See all 20 dosages

  20mg as needed 40mg as needed daily 20 mg weekly 10 mg daily 40 mg m,w,f 20 mg daily 40 mg daily 80 mg daily 160 mg daily
  6 Number of Patients: 6 13 Number of Patients: 13 5 Number of Patients: 5 1 Number of Patients: 1 5 Number of Patients: 5 2 Number of Patients: 2 143 Number of Patients: 143 482 Number of Patients: 482 67 Number of Patients: 67 2 Number of Patients: 2  

Reported Stop Reasons

Why Patients Stopped Taking Esomeprazole (multiple reasons could be selected)
Reason # Patients Percentage of patients
Expense 35   Expense: 23%
Did not seem to work 31   Did not seem to work: 21%
Change in health plan coverage 27   Change in health plan coverage: 18%
Course of treatment ended 25   Course of treatment ended: 17%
Other 25   Other: 17%
Doctor's advice 23   Doctor's advice: 15%
Side effects too severe 9   Side effects too severe: 6%
Personal research 7   Personal research: 5%
Not indicated 3   Not indicated: 2%

See all 144 patients who’ve stopped taking Esomeprazole

Currently Taking Esomeprazole

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Esomeprazole

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Esomeprazole

Always
111 77%
Usually
26 18%
Sometimes
6 4%
Never
1 1%

Burden

Difficulty being on treatment

Burden of Esomeprazole

Very
0 0%
Somewhat
12 8%
A little
18 13%
Not at all
114 79%

Cost

Paid out of pocket

Cost of Esomeprazole

$200+
5 5%
$100-199
4 4%
$50-99
14 14%
$25-49
23 23%
< $25
52 53%

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30 patient evaluations for Esomeprazole

  • moogie16
    Sex: F
    Data Quality: 2 stars
    MS: 51 yrs
    Type: Relapsing-Remitting
    Sensation: Moderate
    Overall: Moderate
    Cognition: moderate
    Vision: moderate
    Speech: moderate
    Swallowing: mild
    Upper limb: moderate
    Walking: moderate
  • 4749-thumb
  • See moogie16's full Esomeprazole history
Purpose: GERD (Gastroesophageal reflux disease) (Started Sep 13, 2010)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Mar 07, 2013   Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Jul 07, 2012 80 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
Purposes: Duodenitis, Gastritis, Acid reflux, and GERD (Gastroesophageal reflux disease) (Started Jun 15, 2012)
Date Dosage Duodenitis Perceived effectiveness Gastritis Perceived effectiveness Acid reflux Perceived effectiveness GERD (Gastroesophageal reflux disease) Perceived effectiveness Side Effects Adherence Burden
Aug 16, 2012 40 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_default Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_default Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4 Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4 NoneNoneNoneNone UsuallyUsuallyUsuallyUsually Not at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
  • shell052169
    Data Quality: 2 stars
    • Sex: M
    • Age: 43y
    • Duration: 32 yrs
    PRO survey: PRO 3
    Quality of Life:
    • Mental: Mild
    • Physical: None
    Surgery type: Vagus Nerve Stimulation (VNS)
    0 seizures
    4 weeks ago
  • 27098-thumb
  • See shell052169's full Esomeprazole history
Purpose: Acid reflux (Started Jan 19, 2002)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Jun 18, 2012 40 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
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What is esomeprazole?

Esomeprazole decreases the amount of acid produced in the stomach.

Esomeprazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Esomeprazole is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

Esomeprazole may also be given to prevent gastric ulcer caused by infection with helicobacter pylori (H. pylori), or by the use of nonsteroidal anti-inflammatory drugs (NSAIDs).

Esomeprazole may also be used for other purposes not listed in this medication guide.


Precautions

Do not use this medication if you are allergic to esomeprazole or to any other benzimidazole medication such as albendazole (Albenza), or mebendazole (Vermox).

Before taking this medication, tell your doctor if you have ever had liver disease or any type of heart disease. You may need a dose adjustment or special tests during treatment.

Some conditions are treated with a combination of esomeprazole and antibiotics. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether esomeprazole passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using esomeprazole.

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Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include confusion, headache, drowsiness, blurred vision, fast heartbeat, nausea, dry mouth, sweating, flushing, shortness of breath, tremor, loss of coordination, or seizure (convulsions).

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

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Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

  • headache;
  • diarrhea;
  • nausea, stomach pain, gas, constipation; or
  • dry mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

Before taking esomeprazole, tell your doctor if you are using any of the following drugs:

  • clopidogrel (Plavix);
  • digoxin (Lanoxin, Lanoxicaps);
  • diazepam (Valium);
  • ketoconazole (Nizoral);
  • HIV or AIDS medication such as atazanavir (Reyataz), nelfinavir (Viracept), saquinavir (Invirase), and others;
  • iron (Feosol, Mol-Iron, Fergon, Femiron, others); or
  • a blood thinner such as warfarin (Coumadin).

This list is not complete and there may be other drugs that can interact with esomeprazole. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Other Names

Nexium, Nexium I.V., and esomeprazole

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Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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