What is oxybutynin?
Oxybutynin reduces muscle spasms of the bladder and urinary tract.
Oxybutynin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased night-time urination.
Oxybutynin may also be used for other purposes not listed in this medication guide.
Do not use this medication if you are allergic to oxybutynin, or if you have:
- untreated or uncontrolled glaucoma;
- a blockage in your digestive tract (stomach or intestines); or
- if you are unable to urinate.
If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before taking oxybutynin, tell your doctor if you have:
- liver disease;
- kidney disease;
- an enlarged prostate;
- ulcerative colitis;
- a blockage in your stomach or intestines;
- a muscle disorder such as myasthenia gravis; or
- a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether oxybutynin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Oxybutynin can cause blurred vision, drowsiness, or dizziness. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease perspiration and you may be more prone to heat stroke.
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Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include restlessness, tingly feeling, fever, uneven heart rate, vomiting, and urinating less than usual or not at all.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using oxybutynin and call your doctor at once if you have any of these serious side effects:
- hot, dry skin and extreme thirst;
- severe stomach pain or constipation;
- pain or burning when you urinate; or
- urinating less than usual or not at all.
Less serious side effects may include:
- dry mouth;
- dry eyes, blurred vision;
- mild constipation;
- nausea, mild stomach pain or upset;
- dizziness, drowsiness, weakness;
- sleep problems; or
- runny nose.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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The following drugs can interact with oxybutynin. Tell your doctor if you are using any of these:
- other bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), tolterodine (Detrol), or solifenacin (Vesicare);
- glycopyrrolate (Robinul);
- flecainide (Tambocor);
- mepenzolate (Cantil);
- thioridazine (Mellaril);
- HIV /AIDS medicine such as nelfinavir (Viracept) or ritonavir (Norvir);
- an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), or troleandomycin (Tao);
- an antifungal medication such as itraconazole (Sporanox) or ketoconazole (Nizoral);
- atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);
- bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);
- irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine); or
- an antidepressant such as amitriptyline (Elavil, Etrafon), fluoxetine (Prozac), fluvoxamine (Luvox), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), and others.
This list is not complete and there are many other drugs that can interact with oxybutynin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
Ditropan, Ditropan XL, Oxytrol, Urotrol, oxybutynin, and Gelnique
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