Senna Treatment Report

Category: Over the Counter Drugs

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Generic Name: Senna

See also: Peri-Colace, Senna S, Senokot-S

What is Senna?

An example of Senna

Senna is a large genus of about 250-260 species of flowering plants containing the substance anthraquinone. This is a natural laxative used as the primary ingredient in certain commercial stimulant laxatives. It can also be made as a tea using senna leaves.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
63 13 Efficacy_major Efficacy_moderate Efficacy_slight
27 4 Efficacy_major Efficacy_moderate
7 2 Efficacy_slight Efficacy_cant_tell
2 1 Efficacy_moderate
1 0
1 1 Efficacy_slight

See all 105 patients currently taking Senna

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Reported Side Effects

Side effects as an overall problem

Severe
1
Moderate
4
Mild
2
None
11

Commonly reported side effects, conditions, and hospitalizations associated with Senna

3
2
2
2
1
1
See all 6 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Senna. See all 46 dosages

  daily 2tab(s) as needed 8.6mg as needed 2 8.6mg as needed 3 8.6mg as needed 8.6 mg daily 17.2 mg daily 34.4 mg daily 43 mg daily 600 mg daily
  5 Number of Patients: 5 2 Number of Patients: 2 7 Number of Patients: 7 3 Number of Patients: 3 2 Number of Patients: 2 10 Number of Patients: 10 27 Number of Patients: 27 8 Number of Patients: 8 2 Number of Patients: 2 2 Number of Patients: 2  

Reported Stop Reasons

Why Patients Stopped Taking Senna (multiple reasons could be selected)
Reason # Patients Percentage of patients
Other 6   Other: 40%
Did not seem to work 2   Did not seem to work: 13%
Doctor's advice 2   Doctor's advice: 13%
Side effects too severe 2   Side effects too severe: 13%
Course of treatment ended 2   Course of treatment ended: 13%
Personal research 1   Personal research: 7%

See all 14 patients who’ve stopped taking Senna

Currently Taking Senna

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Senna

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Senna

Always
9 50%
Usually
6 33%
Sometimes
3 17%
Never
0 0%

Burden

Difficulty being on treatment

Burden of Senna

Very
0 0%
Somewhat
2 11%
A little
8 44%
Not at all
8 44%

Cost

Paid out of pocket

Cost of Senna

$200+
0 0%
$100-199
0 0%
$50-99
0 0%
$25-49
0 0%
< $25
8 100%

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5 patient evaluations for Senna

Purpose: Constipation (Started Mar 01, 2009)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Jul 29, 2012 As needed Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate NoneNoneNoneNoneNone UsuallyUsuallyUsuallyUsuallyUsually A littleA littleA littleA littleA little
  • Icon_thumb_off 0 helpful marks
Purpose: Constipation (Started Jan 01, 2006)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Aug 13, 2011 17.2 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Nov 17, 2010 17.2 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
  • expastrychef
    Sex: M
    Data Quality: 1 star
    MS: 13 yrs
    Type: Secondary Progressive
    Sensation: Moderate
    Overall: Moderate
    Cognition: moderate
    Vision: none
    Speech: mild
    Swallowing: moderate
    Upper limb: moderate
    Walking: moderate
  • 12697-thumb
  • See expastrychef's full Senna history
Purpose: Bowel problems (Started Mar 22, 2008)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Feb 10, 2010 17.2 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways A littleA littleA littleA littleA little
  • Icon_thumb_off 0 helpful marks
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What is senna?

The use of senna in cultural and traditional settings may differ from concepts accepted by current Western medicine. When considering the use of herbal supplements, consultation with a primary health care professional is advisable. Additionally, consultation with a practitioner trained in the uses of herbal/health supplements may be beneficial, and coordination of treatment among all health care providers involved may be advantageous.

Senna is also known as Cassia senna, tinnevelly senna, India senna, Alexandrian senna, and Khartoum senna.

Senna has been used in the treatment of constipation.

Senna has not been evaluated by the FDA for safety, effectiveness, or purity. All potential risks and/or advantages of senna may not be known. Additionally, there are no regulated manufacturing standards in place for these compounds. There have been instances where herbal/health supplements have been sold which were contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Senna may also have uses other than those listed in this product guide.


Precautions

Do not take senna without first talking to your doctor if you have

  • an inflammatory bowel disease such as Crohn's disease or ulcerative colitis,
  • other intestinal problems, or
  • abdominal pain, nausea, or vomiting.

You may not be able to take senna or you may require special monitoring while taking senna if you have any of the conditions listed above.

Also, talk to your doctor before taking senna if you have any other medical conditions, allergies, or if you take other medicines or herbal/health supplements. Senna may not be recommended in some situations.

Do not take senna without first talking to your doctor if you are pregnant or could become pregnant.

Do not take senna without first talking to your doctor if you are breast-feeding a baby.

Some forms of senna are formulated for use by children. Talk to the child’s doctor before using this product to treat a child.

There are no known restrictions on food, beverages, or activity while taking senna, unless otherwise directed by your health care provider.

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Instructions

Seek emergency medical attention.

Symptoms of a senna overdose are not known.

No information is available regarding a missed dose of senna. Consult your doctor, pharmacist, or health care provider if you require further information.

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Side Effects

Although uncommon, allergic reactions to senna have been reported. Stop taking senna and seek emergency medical attention if you experience symptoms of a serious allergic reaction including difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives.

Prolonged use of senna has been reported to cause:

  • chronic diarrhea causing excessive electrolyte and nutrient loss,
  • worsened constipation after senna withdrawal (laxative dependency),
  • enlargement of the ends of the fingers and toes, and
  • pigmentation of the colon.

Notify your doctor if the constipation does not improve after one week of treatment with senna.

Other less serious side effects have also been infrequently reported. Talk to your doctor or pharmacist if you experience

  • abdominal cramping,
  • diarrhea, or
  • discoloration of the urine.

Side effects other than those listed here may also occur. Talk to your doctor, pharmacist, or health care professional about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

There are no reported interactions between senna and other medications. Talk to your doctor, pharmacist, or health care provider before taking any prescription or over-the-counter medicines or other herbal/health supplements.

Other Names

Black Draught, Dosaflex, Dr Caldwell Laxative, Ex-Lax Chocolated, Ex-Lax Gentle Nature, Ex-Lax Maximum Relief Formula, Ex-Lax Regular Strength Pills, Fletchers Castoria, Gentlax, Innerclean, Perdiem Overnight, Senexon, Senna, Senna Lax, Senna-gen, Sennalax, SenoSol, SenoSol-X, Senokot, Senokot Child, Senokot Extra, SenokotXTRA, Senolax, senna, Pedia-Lax, Senna Concentrate, Senna Smooth, Uni-Cenna, and X-Prep

Available Strengths & Dosages


Route Form Strength
oral tablet 8.6 mg
compounding powder -
oral syrup 8.8 mg/5 mL
oral syrup leaf extract 176 mg/5 mL

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Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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