What is Nitrofurantoin?

An example of Nitrofurantoin

Nitrofurantoin is an antibiotic that is used to prevent and treat urinary tract infections caused by susceptible strains of E. coli, S. aureus, Enterococcus, Klebsiella, and Enterobacter.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
42 5 Efficacy_major Efficacy_moderate Efficacy_cant_tell
34 18 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
32 6 Efficacy_major Efficacy_moderate
4 3 Efficacy_major Efficacy_moderate Efficacy_cant_tell
3 0
3 1 Efficacy_major

See all 97 patients currently taking Nitrofurantoin

Mouse over the table for more information

Reported Side Effects

Side effects as an overall problem

Severe
0
Moderate
5
Mild
6
None
26

Reported Dosages

Frequently reported dosages based on patients currently taking Nitrofurantoin. See all 20 dosages

  macrocrystals-monohydrate100mg as needed macrocrystals50mg as needed macrocrystals100mg as needed daily 25 mg daily 50 mg daily 75 mg daily 100 mg daily 150 mg daily 200 mg daily
  2 Number of Patients: 2 2 Number of Patients: 2 2 Number of Patients: 2 5 Number of Patients: 5 7 Number of Patients: 7 25 Number of Patients: 25 11 Number of Patients: 11 25 Number of Patients: 25 3 Number of Patients: 3 4 Number of Patients: 4  

Reported Stop Reasons

Why Patients Stopped Taking Nitrofurantoin (multiple reasons could be selected)
Reason # Patients Percentage of patients
Course of treatment ended 31   Course of treatment ended: 61%
Doctor's advice 9   Doctor's advice: 18%
Other 6   Other: 12%
Side effects too severe 3   Side effects too severe: 6%
Did not seem to work 2   Did not seem to work: 4%
Personal research 1   Personal research: 2%

See all 48 patients who’ve stopped taking Nitrofurantoin

Currently Taking Nitrofurantoin

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Nitrofurantoin

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Nitrofurantoin

Always
29 78%
Usually
6 16%
Sometimes
1 3%
Never
1 3%

Burden

Difficulty being on treatment

Burden of Nitrofurantoin

Very
0 0%
Somewhat
4 11%
A little
3 8%
Not at all
30 81%

Cost

Paid out of pocket

Cost of Nitrofurantoin

$200+
1 5%
$100-199
0 0%
$50-99
1 5%
$25-49
2 9%
< $25
18 82%

Sort by: Helpfulness | Most Recent

11 patient evaluations for Nitrofurantoin

Purpose: Prevent infection (Started Jan 21, 2013)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Apr 20, 2013 100 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate MildMildMildMildMild AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Date
Apr 20, 2013
Advice & Tips
Had started antibiotic forgetting NOT to take Cranberry caps as it interfears with it. Stopped mid way through same on advice of MS Nurse Specialist. Brainfog!!!
Cost
< $25 monthly
  • Icon_thumb_off 0 helpful marks
  • jmellow
    Sex: F
    Data Quality: 3 stars
    MS: 19 yrs
    Type: Relapsing-Remitting
    Sensation: Moderate
    Overall: Mild
    Cognition: moderate
    Vision: none
    Speech: mild
    Swallowing: none
    Upper limb: mild
    Walking: mild
  • 11599-thumb
  • See jmellow's full Nitrofurantoin history
Purpose: UTI (Urinary Tract Infection) (Started Sep 18, 2012)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Sep 22, 2012 200 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate ModerateModerateModerateModerateModerate AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Date
Sep 22, 2012
Advice & Tips
Take with food and a lot of fluids
Cost
< $25 monthly
  • Icon_thumb_off 0 helpful marks
  • Jazz1982
    Sex: F
    Data Quality: 2 stars
    MS: 6 yrs
    Type: Relapsing-Remitting
    Sensation: None
    Overall: None
    Cognition: none
    Vision: none
    Speech: none
    Swallowing: none
    Upper limb: none
    Walking: none
  • 44931-thumb
  • See Jazz1982's full Nitrofurantoin history
Purpose: UTI symptoms (Started May 09, 2012)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Jul 26, 2012   Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate NoneNoneNoneNoneNone UsuallyUsuallyUsuallyUsuallyUsually A littleA littleA littleA littleA little
  • Icon_thumb_off 0 helpful marks
1 2 3 4    You are at the first page First There is no previous page Prev | Next Go to the next page Last Go to the last page 

What is nitrofurantoin?

Nitrofurantoin is an antibiotic that fights bacteria in the body.

Nitrofurantoin is used to treat urinary tract infections.

Nitrofurantoin may also be used for other purposes not listed in this medication guide.


Precautions

You should not use this medication if you are allergic to nitrofurantoin, or if you have:

  • severe kidney disease;
  • a history of jaundice or liver problems caused by taking nitrofurantoin;
  • if you are urinating less than usual or not at all; or
  • if you are in the last 2 to 4 weeks of pregnancy.

If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before taking nitrofurantoin, tell your doctor if you have:

  • kidney disease;
  • anemia;
  • diabetes;
  • an electrolyte imbalance or vitamin B deficiency;
  • glucose-6-phosphate dehydrogenase (G6PD) deficiency; or
  • any type of debilitating disease.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby, unless it is used during the last 2 to 4 weeks of pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Nitrofurantoin passes into breast milk and may harm a nursing baby. Do not take this medication without telling your doctor if you are breast feeding a baby.

Do not give nitrofurantoin to a child younger than 12 years old.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Avoid using antacids without your doctor’s advice. Use only the specific type of antacid your doctor recommends. Antacids contain different medicines and some types can make it harder for your body to absorb nitrofurantoin.

Back to top

Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea or vomiting.

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

Back to top

Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • diarrhea that is watery or bloody;
  • shortness of breath, running out of breath easily;
  • fever, chills, cough, chest pain;
  • nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • pale skin, easy bruising, confusion or weakness;
  • numbness or tingling; or
  • headache, ringing in your ears, dizziness, vision problems, pain behind your eyes;

Less serious side effects may include:

  • rust-colored or brownish urine;
  • headache;
  • upset stomach, vomiting;
  • bloating or gas, constipation;
  • feeling dizzy or drowsy;
  • blurred vision; or
  • vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Back to top

Interactions

Before taking nitrofurantoin, tell your doctor if you are taking:

  • magnesium salicylate (Doan's Pills, Mobidin, Momentum);
  • choline magnesium salicylate (Tricosal, Trilisate);
  • probenecid (Benemid); or
  • sulfinpyrazone (Anturane).

This list is not complete and there may be other drugs that can interact with nitrofurantoin. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Other Names

Furadantin, Macrobid, Macrodantin, Nitro Macro, and nitrofurantoin

Back to top

Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

Last updated: