What is pancrelipase?
Pancrelipase is a combination of three enzymes (proteins): lipase, protease, and amylase. These enzymes are normally produced by the pancreas and are important in the digestion of fats, proteins, and sugars.
Pancrelipase is used to replace these enzymes when the body does not have enough of its own. Certain medical conditions can cause this lack of enzymes, including cystic fibrosis, chronic inflammation of the pancreas, or blockage of the pancreatic ducts.
Pancrelipase may also be used following surgical removal of the pancreas.
Pancrelipase may also be used for purposes other than those listed in this medication guide.
You should not take pancrelipase if you are allergic to pork proteins.
Before taking pancrelipase, tell your doctor if you are allergic to any drugs, or if you have:
- a sudden onset of pancreatitis; or
- worsening of chronic pancreatic disease.
If you have any of these conditions, you may need a dose adjustment or special tests to safely use this medication.
This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether pancrelipase passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Follow your doctor’s instructions about any restrictions on food, beverages, or activity while you are using pancrelipase.
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Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include diarrhea or stomach upset.
Skip the missed dose and wait until your next scheduled dose to take the medicine. Do not take extra medicine to make up the missed dose.
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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Less serious side effects may include:
- nausea or vomiting;
- stomach pain or upset;
- diarrhea or constipation;
- greasy stools;
- rectal irritation; or
- bloating or gas.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
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This list is not complete and there may be other drugs that can interact with pancrelipase. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Arco-Lase, Cotazym, Cotazym-S, Creon 10, Creon 20, Creon 5, Dygase, Encron-10, Ilozyme, Ku-Zyme, Ku-Zyme HP, Kutrase, Lapase, Lipram-CR, Lipram-CR5, Lipram-UL 12, Lipram-UL 18, Palcaps 10, Panase, Pancrease MT 10, Pancrease MT 16, Pancrease MT 20, Pancrease MT 4, Pancrecarb MS-16, Pancrecarb MS-4, Pancrecarb MS-8, Pancron D/R, Panocaps, Panocaps MT 16, Protilase, Protilase MT-16, Ultrase, Ultrase MT 12, Ultrase MT 18, Ultrase MT 20, Vio-Moore, Viokase, Viokase 16, Viokase 8, Zymase, pancrelipase, Lipram, Lipram-CR10, Lipram-CR20, Lipram-PN10, Lipram-PN16, Lipram-PN20, Lipram-UL 20, Pancrease, Pancreatil-UL 12, Pangestyme CN 10, Pangestyme CN 20, Pangestyme EC, Pangestyme MT 16, Pangestyme UL 18, Pangestyme UL 20, Panokase, Panokase 16, and Plaretase
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Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04