What is basiliximab?
Basiliximab lowers your body’s immune system. The immune system helps your body fight infections. The immune system can also fight or "reject” a transplanted organ such as a liver or kidney. This is because the immune system treats the new organ as an invader.
Basiliximab is used with other medications to prevent organ rejection after a kidney transplant.
Basiliximab may also be used for purposes other than those listed in this medication guide.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether basiliximab passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Avoid contact with people who have colds, the flu, or other contagious illnesses. Contact your doctor immediately if you develop signs of infection.
Avoid receiving a vaccine shortly after you have been treated with basiliximab, unless your doctor has told you to.
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An overdose of basiliximab is not expected to produce life-threatening symptoms.
Since basiliximab is given while you are in the hospital, it is unlikely that you will miss a dose.
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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- pain or burning when you urinate;
- easy bruising or bleeding, unusual weakness;
- sleep problems (insomnia);
- tremors, shaking; or
- fever, chills, body aches, flu symptoms.
Other less serious side effects are more likely to occur, such as:
- nausea, vomiting, constipation, stomach pain;
- diarrhea, constipation; or
- swelling in your hands, ankles, or feet.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
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Before receiving basiliximab, tell your doctor if you are using any drugs that weaken your immune system, such as:
- chemotherapy or radiation;
- steroid medicine;
- sirolimus (Rapamune), tacrolimus (Prograf);
- efalizumab (Raptiva), muromonab-CD3 (Orthoclone);
- mycophenolate mofetil (CellCept); or
- azathioprine (Imuran), leflunomide (Arava), etanercept (Enbrel).
If you are using any of these drugs, you may not be able to receive basiliximab, or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect basiliximab. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Simulect and basiliximab
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