Isradipine Treatment Report

Category: Prescription Drugs

Most Popular Types: DynaCirc CR, DynaCirc

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What is Isradipine?

An example of Isradipine

Isradipine is a calcium channel blocker of the dihydropyridine class. It is usually prescribed for the treatment of high blood pressure in order to reduce the risk of stroke and heart attack. More recent research suggests that isradipine may have potential uses for treating Parkinson's disease.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
16 4 Efficacy_major Efficacy_cant_tell
7 1 Efficacy_major
2 0
1 0
1 1 Efficacy_moderate

See all 25 patients currently taking Isradipine

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Reported Side Effects

Side effects as an overall problem

Severe
2
Moderate
0
Mild
0
None
7

Commonly reported side effects, conditions, and hospitalizations associated with Isradipine

1
1
1
1

Reported Dosages

  daily 2.5 mg daily 5 mg daily 7.5 mg daily 10 mg daily 20 mg daily
  1 Number of Patients: 1 3 Number of Patients: 3 8 Number of Patients: 8 1 Number of Patients: 1 8 Number of Patients: 8 4 Number of Patients: 4  

Reported Stop Reasons

Why Patients Stopped Taking Isradipine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Expense 3   Expense: 38%
Course of treatment ended 2   Course of treatment ended: 25%
Not indicated 2   Not indicated: 25%
Doctor's advice 2   Doctor's advice: 25%
Did not seem to work 2   Did not seem to work: 25%
Side effects too severe 1   Side effects too severe: 13%
Other 1   Other: 13%

See all 8 patients who’ve stopped taking Isradipine

Currently Taking Isradipine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0
0

Stopped Taking Isradipine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Isradipine

Always
8 89%
Usually
1 11%
Sometimes
0 0%
Never
0 0%

Burden

Difficulty being on treatment

Burden of Isradipine

Very
1 11%
Somewhat
0 0%
A little
2 22%
Not at all
6 67%

Cost

Paid out of pocket

Cost of Isradipine

$200+
0 0%
$100-199
0 0%
$50-99
2 40%
$25-49
1 20%
< $25
2 40%

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4 patient evaluations for Isradipine

Purpose: Other (Started Mar 29, 2008)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Jul 22, 2012 7.5 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways A littleA littleA littleA littleA little
Sep 29, 2008 7.5 mg Daily Led_efficacy_2Led_efficacy_2Led_defaultLed_defaultSlight NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Aug 20, 2008 7.5 mg Daily Led_efficacy_2Led_efficacy_2Led_defaultLed_defaultSlight NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Date
Sep 29, 2008
Advice & Tips
My blood pressure is running quite high with this medication. I am in the process of switching back to my former treatment of Lisinopril.
  • Icon_thumb_on 1 helpful mark
Purposes: Support circulatory health and Parkinson's Disease (Started Feb 14, 2011)
Date Dosage Support circulatory health Perceived effectiveness Parkinson's Disease Perceived effectiveness Side Effects Adherence Burden
Nov 10, 2011 5 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate ?Can't tell NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways A littleA littleA littleA littleA little
Feb 28, 2011 5 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate ?Can't tell MildMildMildMildMild AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Side effects:
Swelling in feet
Date
Feb 28, 2011
Advice & Tips
I experienced some swelling in my feet. This improved when HCT 12.3 mg was added to my BP meds.
Cost
$25-49 monthly
  • Icon_thumb_off 0 helpful marks
Purpose: Elevated blood pressure (Started Sep 15, 2009)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Jan 19, 2010 5 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Dec 07, 2009 5 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways SomewhatSomewhatSomewhatSomewhatSomewhat
Date
Dec 07, 2009
Advice & Tips
I have found that my tremors from PD have seemed to have lowered.
Cost
$25-49 monthly
  • Icon_thumb_on 1 helpful mark
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What is isradipine?

Isradipine is in a group of drugs called calcium channel blockers. It works by relaxing the muscles of your heart and blood vessels.

Isradipine is used to treat high blood pressure (hypertension). It is sometimes given with other blood pressure medications.

Isradipine may also be used for purposes other than those listed in this medication guide.


Precautions

You should not take this medication if you are allergic to isradipine.

Before taking isradipine, tell your doctor if you are allergic to any drugs, or if you have:

  • kidney disease;
  • liver disease;
  • congestive heart failure; or
  • a narrowing or blockage in your digestive tract.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take isradipine.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Isradipine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Isradipine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

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Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include fast heart rate, sluggish feeling, or feeling like you might pass out.

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

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Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • feeling like you might pass out;
  • feeling short of breath, even with mild exertion;
  • swelling in your hands and feet;
  • fast or pounding heartbeats; or
  • chest pain.

Less serious side effects may include:

  • dizziness;
  • warmth, redness, or tingly feeling under your skin;
  • headache;
  • weakness, tired feeling;
  • nausea, vomiting, diarrhea, upset stomach; or
  • skin rash or itching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

Before taking isradipine, tell your doctor if you are using any of the following drugs:

  • cimetidine (Tagamet, Tagamet HB);
  • fentanyl (Duragesic, Ionsys, Actiq); or
  • rifampin (Rifadin, Rimactane, Rifater).

This list is not complete and there may be other drugs that can interact with isradipine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Other Names

Dynacirc, Dynacirc CR, and isradipine

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Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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