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Home > Community Treatment Reports and Side Effects > Dornase alfa Treatment Report
What is Dornase alfa?

Dornase alfa is an enzyme used with cystic fibrosis patients to reduce the frequency of respiratory infections that require IV antibiotics; in conjunction with standard therapies, it is used to improve pulmonary function in patients with cystic fibrosis.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Cystic Fibrosis 66 2 Efficacy_major
Increased secretions 2 1 Efficacy_major
cystic fibrosis 1 0
Other 1 0

See all 68 patients currently taking Dornase alfa

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Reported Side Effects

Side effects as an overall problem

Severe
 0
Moderate
 0
Mild
 0
None
 3

Reported Dosages

  1 mg daily 2.5 mg/2.5 mL m,w,f 2 mg daily 2.5 mg/2.5 mL daily 2 x 2.5 mg/2.5 mL daily 5 mg daily
  1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 45 Number of Patients: 45 21 Number of Patients: 21 1 Number of Patients: 1  

Reported Stop Reasons

Why Patients Stopped Taking Dornase alfa (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 2   Did not seem to work: 25%
Change in health plan coverage 2   Change in health plan coverage: 25%
Not indicated 2   Not indicated: 25%
Doctor's advice 1   Doctor's advice: 13%
Side effects too severe 1   Side effects too severe: 13%
Other 1   Other: 13%

See all 8 patients who’ve stopped taking Dornase alfa

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Dornase alfa

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Dornase alfa

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Dornase alfa

Always
 2 67%
Usually
 1 33%
Sometimes
 0 0%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Dornase alfa

Very
 0 0%
Somewhat
 0 0%
A little
 2 67%
Not at all
 1 33%

Cost

Paid out of pocket

Cost of Dornase alfa

$200+
 0 0%
$100-199
 0 0%
$50-99
 0 0%
$25-49
 0 0%
< $25
 0 0%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 28, 2012.