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Brand Names: Methotrexate IV Trial

What is Methotrexate? Methotrexate is an antineoplastic drug used in the treatment of cancer. Also used as an antirheumatic for rheumatoid arthritis. Off label use in treatment of Crohn's disease and ectopic pregnancy. Experimental use in MS. It is given as an IM or SC injection, via IV or intrathecally.

See more information, including instructions, precautions, side effects, and interactions.


Reasons Taken

56 patients in the community are taking or have taken Methotrexate.

Reason # Patients Percentage of patients
Slow my MS progress 30 53%
Other 20 35%
Pain 4 7%
Slow my Devic's progress 1 1%
Depression 1 1%

Dosages

Based on the patients currently taking Methotrexate.

Top 10 (Show all)

All (Show Top 10)

  0 g none 0 none 3 mg week 3.5 mg week 7.5 mg week 10 mg week 12.5 mg week 15 mg week 17 mg week 17.5 mg week 18 mg week 20 mg week 25 mg week 10 mg day 15 mg day
  1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 4 Number of Patients: 4 4 Number of Patients: 4 2 Number of Patients: 2 4 Number of Patients: 4 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1 5 Number of Patients: 5 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1  

Duration

How long current patients have been taking Methotrexate or how long patients were taking Methotrexate before stopping.

Currently taking Methotrexate

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
1
1
5
3
7
12

Stopped taking Methotrexate

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
1
0
2
3
1
5
Why Patients Stopped Taking Methotrexate (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 4 33% Side effects too severe: 33%
Did not seem to work 3 25% Did not seem to work: 25%
Doctor's advice 2 17% Doctor's advice: 17%
Course of treatment ended 2 17% Course of treatment ended: 17%
Personal research 1 8% Personal research: 8%
Other 1 8% Other: 8%
Not indicated 1 8% Not indicated: 8%

Patient Reported Evaluations

Results from 5 patient evaluations. See the overall results and all individual evaluations.

Efficacy (Effect based on reason taken)

Major 67% 2
Moderate 33% 1

Other

Side-effects (as an overall problem)

Severe 0% 0
Moderate 40% 2
Mild 20% 1
None 40% 2

Top reported side-effects include: Mouth sores/ulcers, stomach upset, hair loss

Summary results are based on 5 individual responses. For more information, see overall results for Adherence, Burden and Cost.

Individual Patient Reported Evaluations (2 of 5)

  • pokie too
    Mouth/throat: mild
    Arms: mild
    Chest: mild
    Legs: mild
    See profile
  • pokie too
  • by pokie too
    Aug 19, 2008
  • EfficacyMajor
  • Side-effectsMild
  • Other
Advice/Tips
does cause hair thinning

  • shuffles
    Sensation: Severe
    Overall: Moderate
    Cognition: moderate
    Vision: moderate
    Speech: moderate
    Swallowing: moderate
    Upper limb: moderate
    Walking: moderate
    See profile
  • shuffles
  • by shuffles
    Sep 09, 2008
  • EfficacyMajor
  • Side-effectsNone
  • Pain
Advice/Tips
this medication works well combined with other medication for rheamatoid arthritis.

See all evaluation results for Methotrexate



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