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What is Selegiline?

Selegiline is an antidepressant and anti-Parkinson's agent. Orally it is used as an adjunct to levodopa/carbidopa therapy for Parkinson's disease; transdermally it is used for major depressive disorder. Off label it is used for ADHD; negative symptoms of schizophrenia and extrapyramidal symptoms.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Parkinson's Disease 240 47 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Depressed mood 22 15 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Stiffness/Spasticity 11 1 Efficacy_none
Other 10 4 Efficacy_moderate Efficacy_slight Efficacy_none
Treat my mood condition(s) 9 3 Efficacy_moderate Efficacy_none
Major Depressive Disorder 8 4 Efficacy_major Efficacy_none

See all 229 patients currently taking Selegiline

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Reported Side Effects

Side effects as an overall problem

Severe
13
Moderate
8
Mild
14
None
43

Reported Dosages

Frequently reported dosages based on patients currently taking Selegiline. See all 25 dosages

  daily 1.25 mg daily 2.5 mg daily 5 mg daily 6 mg/24 hr daily 9 mg/24 hr daily 10 mg daily 12 mg/24 hr daily 15 mg daily 20 mg daily
  6 Number of Patients: 6 12 Number of Patients: 12 18 Number of Patients: 18 56 Number of Patients: 56 5 Number of Patients: 5 6 Number of Patients: 6 97 Number of Patients: 97 5 Number of Patients: 5 6 Number of Patients: 6 4 Number of Patients: 4  

Reported Stop Reasons

Why Patients Stopped Taking Selegiline (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 51   Did not seem to work: 37%
Doctor's advice 42   Doctor's advice: 31%
Side effects too severe 27   Side effects too severe: 20%
Other 23   Other: 17%
Personal research 12   Personal research: 9%
Expense 6   Expense: 4%
Course of treatment ended 3   Course of treatment ended: 2%
Not indicated 3   Not indicated: 2%
Change in health plan coverage 2   Change in health plan coverage: 1%

See all 130 patients who’ve stopped taking Selegiline

Currently Taking Selegiline

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0

Stopped Taking Selegiline

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Selegiline

Always
60 77%
Usually
10 13%
Sometimes
2 3%
Never
6 8%

Burden

Difficulty being on treatment

Burden of Selegiline

Very
5 6%
Somewhat
7 9%
A little
12 15%
Not at all
54 69%

Cost

Paid out of pocket

Cost of Selegiline

$200+
2 4%
$100-199
1 2%
$50-99
7 14%
$25-49
14 29%
< $25
25 51%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 28, 2012.