Lacosamide Treatment Report

Category: Prescription Drugs

Most Popular Types: Vimpat

false

What is Lacosamide?

An example of Lacosamide

Lacosamide is an anticonvulsant agent used for adjunctive therapy in the treatment of partial-onset seizures. Lacosamide was previously known as harkoseride and then SPM 927.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
259 94 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
42 19 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
10 4 Efficacy_major Efficacy_slight Efficacy_cant_tell
4 1 Efficacy_slight
2 0
1 0

See all 276 patients currently taking Lacosamide

Mouse over the table for more information

Reported Side Effects

Side effects as an overall problem

Severe
18
Moderate
27
Mild
38
None
29

Commonly reported side effects, conditions, and hospitalizations associated with Lacosamide

10
10
7
6
6
4
See all 111 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Lacosamide. See all 30 dosages

  50 mg daily 100 mg daily 150 mg daily 200 mg/20 mL daily 200 mg daily 300 mg daily 400 mg daily 2 x 200 mg/20 mL daily 500 mg daily 600 mg daily
  17 Number of Patients: 17 49 Number of Patients: 49 6 Number of Patients: 6 9 Number of Patients: 9 60 Number of Patients: 60 31 Number of Patients: 31 63 Number of Patients: 63 17 Number of Patients: 17 5 Number of Patients: 5 10 Number of Patients: 10  

Reported Stop Reasons

Why Patients Stopped Taking Lacosamide (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 28   Did not seem to work: 46%
Side effects too severe 26   Side effects too severe: 43%
Doctor's advice 14   Doctor's advice: 23%
Other 8   Other: 13%
Expense 8   Expense: 13%
Course of treatment ended 2   Course of treatment ended: 3%
Change in health plan coverage 2   Change in health plan coverage: 3%
Not indicated 2   Not indicated: 3%

See all 60 patients who’ve stopped taking Lacosamide

Currently Taking Lacosamide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Lacosamide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Lacosamide

Always
102 91%
Usually
6 5%
Sometimes
2 2%
Never
2 2%

Burden

Difficulty being on treatment

Burden of Lacosamide

Very
5 4%
Somewhat
11 10%
A little
16 14%
Not at all
80 71%

Cost

Paid out of pocket

Cost of Lacosamide

$200+
8 11%
$100-199
5 7%
$50-99
6 8%
$25-49
11 15%
< $25
41 58%

Sort by: Helpfulness | Most Recent

16 patient evaluations for Lacosamide

Purpose: Epilepsy (Started Nov 10, 2012)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Dec 23, 2012 200 mg Daily ?Can't tell ?Can't tell ?Can't tell NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Nov 11, 2012 200 mg Daily ?Can't tell ?Can't tell ?Can't tell NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
Purpose: Epilepsy (Started Jul 01, 2009)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Feb 11, 2012 600 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate ModerateModerateModerateModerateModerate AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
Purpose: Epilepsy (Started Dec 13, 2009)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Feb 01, 2012 200 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Date
Feb 01, 2012
Advice & Tips
Just try it, you may have to get used to it at first. It improved my overall motor skills.
  • Icon_thumb_off 0 helpful marks
1 2 3 4 5 6    You are at the first page First There is no previous page Prev | Next Go to the next page Last Go to the last page 

What is lacosamide?

Lacosamide is an antiepileptic drug.

Lacosamide is used together with other medications to treat partial-onset seizures in people with epilepsy who are at least 17 years old.

Lacosamide may also be used for other purposes not listed in this medication guide.


Precautions

You should not use this medication if you are allergic to lacosamide.

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take lacosamide, tell your doctor if you have:

  • kidney disease;
  • liver disease; or
  • a serious heart condition such as "AV block," heart failure, or sick sinus syndrome (unless you have a pacemaker).

You may have thoughts about suicide while taking this medication. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

FDA pregnancy category C. It is not known whether lacosamide is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

Your name may need to be listed on a antiepileptic drug pregnancy registry if you become pregnant while you are taking this medication. The purpose of this registry is to track the outcome of the pregnancy and delivery to evaluate whether lacosamide had any effect on the baby.

It is not known whether lacosamide passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medication to a child younger than 17 years old.

Lacosamide can cause side effects that may impair your vision or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Back to top

Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose can cause dizziness, blurred vision, confusion, fast heart rate, or fainting.

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

Back to top

Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, panic, or if you feel hyperactive, talkative, restless, agitated, aggressive, angry, impulsive, or have thoughts about suicide or hurting yourself.

Stop using lacosamide and call your doctor at once if you have a serious side effect such as:

  • confusion, thoughts of hurting yourself;
  • double vision;
  • feeling like you might pass out;
  • fast or pounding heartbeats;
  • feeling short of breath;
  • fever, swollen glands, easy bruising or bleeding;
  • nausea, pain in your upper stomach, jaundice (yellowing of your skin or eyes);
  • skin rash, bruising, severe tingling, numbness, pain, muscle weakness; or
  • lower back pain, cloudy or bloody urine, swelling, rapid weight gain, urinating less than usual.

Less serious side effects may include:

  • headache, ringing in your ears;
  • tremors, muscle spasms, numbness or tingly feeling;
  • drowsiness, trouble concentrating;
  • dizziness, spinning sensation;
  • loss of balance or coordination;
  • constipation, diarrhea, upset stomach, vomiting; or
  • blurred vision.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

Back to top

Interactions

There may be other drugs that can interact with lacosamide. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Other Names

lacosamide and Vimpat

Back to top

Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

Last updated: