What is guanfacine?
Guanfacine reduces nerve impulses in your heart and blood vessels. Guanfacine works by relaxing blood vessels, which lowers blood pressure and improves blood flow.
Guanfacine is used to treat high blood pressure (hypertension). It is sometimes given together with other blood pressure medications.
Guanfacine may also be used for other purposes not listed in this medication guide.
You should not use this medication if you are allergic to guanfacine.
Before taking guanfacine, tell your doctor if you are allergic to any drugs, or if you have:
- heart disease;
- coronary artery disease or a history of stroke;
- kidney disease;
- liver disease; or
- if you have recently had a heart attack.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take guanfacine.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether guanfacine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Guanfacine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid drinking alcohol. It can increase some of the side effects of guanfacine.
Tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by guanfacine.
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Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include drowsiness, weakness, slow heart rate, or feeling like you might pass out.
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- fast or slow heart rate;
- pounding heartbeats, chest tightness;
- numbness or tingling; or
- feeling like you might pass out.
Less serious side effects may include:
- drowsiness, dizziness;
- dry mouth;
- sleep problems (insomnia);
- constipation, diarrhea;
- stomach pain;
- impotence, loss of interest in sex; or
- mild itching or skin rash.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
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The following drugs can interact with guanfacine. Tell your doctor if you are using any of these:
- a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Luminal, Solfoton);
- diazepam (Valium) or similar medicines such as alprazolam (Xanax), lorazepam (Ativan), temazepam (Restoril), triazolam (Halcion), and others; or
- phenothiazines such as chlorpromazine (Thorazine), mesoridazine (Serentil), prochlorperazine (Compazine), thioridazine (Mellaril), and others.
This list is not complete and there may be other drugs that can interact with guanfacine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Tenex and guanfacine
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Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04