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What is Cyclophosphamide?

Cyclophosphamide is a nitrogen mustard alkylating agent that is used to treat various types of cancer. It is also used to prevent transplant rejection and autoimmune disorders; rheumatoid disorders, myasthenia gravis, nephrotic syndrome, multiple scelrosis, lupus and certain blood disorders.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
MS (Multiple Sclerosis) 52 29 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Lupus Nephritis 11 2 Efficacy_major
Other 8 3 Efficacy_moderate Efficacy_none Efficacy_cant_tell
Wegener's granulomatosis 8 3 Efficacy_major Efficacy_moderate Efficacy_slight
Systemic Lupus Erythematosus 6 2 Efficacy_major Efficacy_cant_tell
Improve mobility 5 1 Efficacy_moderate

See all 37 patients currently taking Cyclophosphamide

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Reported Side Effects

Side effects as an overall problem

Severe
 9
Moderate
 14
Mild
 15
None
 6

Commonly reported side effects, conditions, and hospitalizations associated with Cyclophosphamide

Nausea 12
Hair loss 12
Fatigue 8
Constipation 6
Vomiting 4
Nausea and vomiting 3
See all 28 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Cyclophosphamide. See all 23 dosages ►

  monthly 1 g monthly 100 mg monthly 200 mg monthly 25 mg daily 1,000 mg monthly 500 mg every other week 1,100 mg monthly 50 mg daily 100 mg daily
  3 Number of Patients: 3 7 Number of Patients: 7 2 Number of Patients: 2 4 Number of Patients: 4 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 2 Number of Patients: 2 3 Number of Patients: 3  

Reported Stop Reasons

Why Patients Stopped Taking Cyclophosphamide (multiple reasons could be selected)
Reason # Patients Percentage of patients
Course of treatment ended 51   Course of treatment ended: 59%
Did not seem to work 21   Did not seem to work: 24%
Doctor's advice 16   Doctor's advice: 19%
Side effects too severe 16   Side effects too severe: 19%
Other 8   Other: 9%
Personal research 3   Personal research: 3%

See all 85 patients who’ve stopped taking Cyclophosphamide

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Cyclophosphamide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Cyclophosphamide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Cyclophosphamide

Always
 41 93%
Usually
 1 2%
Sometimes
 0 0%
Never
 2 5%

Burden

Difficulty being on treatment

Burden of Cyclophosphamide

Very
 9 20%
Somewhat
 16 36%
A little
 7 16%
Not at all
 12 27%

Cost

Paid out of pocket

Cost of Cyclophosphamide

$200+
 3 12%
$100-199
 0 0%
$50-99
 2 8%
$25-49
 2 8%
< $25
 18 72%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 28, 2012.