Clonazepam Treatment Report

Category: Prescription Drugs

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Generic Name: Clonazepam

What is Clonazepam?

An example of Clonazepam

Clonazepam, a benzodiazepine, is used alone or as an adjunct in the treatment of seizure disorders and for panic disorders. Off label it is used for restless leg syndrome, neuralgia, multifocal tic disorder, parkinsonian dysarthria, bipolar disorder and as an adjunct in treatment of schizophrenia.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
1,399 404 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
390 75 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
371 119 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
317 76 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
246 81 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
193 46 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell

See all 3,470 patients currently taking Clonazepam

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Reported Side Effects

Side effects as an overall problem

Severe
69
Moderate
163
Mild
321
None
423

Commonly reported side effects, conditions, and hospitalizations associated with Clonazepam

131
73
54
38
34
25
See all 195 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Clonazepam. See all 122 dosages

  0.5mg as needed 1mg as needed 0.125 mg daily 0.25 mg daily 0.5 mg daily 1 mg daily 1.5 mg daily 2 mg daily 3 mg daily 4 mg daily
  297 Number of Patients: 297 160 Number of Patients: 160 69 Number of Patients: 69 111 Number of Patients: 111 603 Number of Patients: 603 854 Number of Patients: 854 207 Number of Patients: 207 483 Number of Patients: 483 197 Number of Patients: 197 136 Number of Patients: 136  

Reported Stop Reasons

Why Patients Stopped Taking Clonazepam (multiple reasons could be selected)
Reason # Patients Percentage of patients
Doctor's advice 203   Doctor's advice: 32%
Did not seem to work 183   Did not seem to work: 29%
Other 146   Other: 23%
Side effects too severe 137   Side effects too severe: 21%
Course of treatment ended 66   Course of treatment ended: 10%
Personal research 31   Personal research: 5%
Expense 20   Expense: 3%
Not indicated 16   Not indicated: 3%
Change in health plan coverage 13   Change in health plan coverage: 2%

See all 609 patients who’ve stopped taking Clonazepam

Currently Taking Clonazepam

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Clonazepam

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Clonazepam

Always
666 68%
Usually
197 20%
Sometimes
93 10%
Never
20 2%

Burden

Difficulty being on treatment

Burden of Clonazepam

Very
30 3%
Somewhat
64 7%
A little
149 15%
Not at all
733 75%

Cost

Paid out of pocket

Cost of Clonazepam

$200+
3 0%
$100-199
3 0%
$50-99
13 2%
$25-49
64 10%
< $25
581 88%

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186 patient evaluations for Clonazepam

  • carlo
    Data Quality: 1 star
    • Sex: M
    • Age: 69y
    • Duration: 37 yrs
    PRO survey: PRO 3
    Quality of Life:
    • Mental: Mild
    • Physical: None
    0 seizures
    1 week ago
  • Portrait_default_thumb
  • See carlo's full Clonazepam history
Purposes: Epilepsy and Anxious mood (Started Oct 10, 1988)
Date Dosage Epilepsy Perceived effectiveness Anxious mood Perceived effectiveness Side Effects Adherence Burden
May 12, 2013 4 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
May 01, 2011 4 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Nov 19, 2009 4 mg Daily Led_efficacy_2Led_efficacy_2Led_defaultLed_defaultSlight NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Date
May 12, 2013
Advice & Tips
I am able to function normally on a day to day basis. I travel w/o anxiety. participate in groups. take walks. ride the subway.etc.
Cost
< $25 monthly
Date
May 01, 2011
Advice & Tips
no problem
Cost
$25-49 monthly
Date
Nov 19, 2009
Advice & Tips
fewer anxiety attacks.
Cost
$25-49 monthly
  • Icon_thumb_off 0 helpful marks
  • gkygrl
    Sex: F
    Data Quality: 3 stars
    MS: 22 yrs
    Type: Relapsing-Remitting
    Sensation: Moderate
    Overall: Moderate
    Cognition: moderate
    Vision: moderate
    Speech: mild
    Swallowing: moderate
    Upper limb: mild
    Walking: moderate
  • 7484-thumb
  • See gkygrl's full Clonazepam history
Purposes: MS hug (tight chest or torso), Insomnia, Stiffness/Spasticity, and Anxious mood (Started Jun 23, 2009)
Date Dosage MS hug (tight chest or torso) Perceived effectiveness Insomnia Perceived effectiveness Stiffness/Spasticity Perceived effectiveness Anxious mood Perceived effectiveness Side Effects Adherence Burden
May 01, 2013 0.25 mg Daily Led_efficacy_1Led_defaultLed_defaultLed_default Led_efficacy_2Led_efficacy_2Led_defaultLed_default Led_efficacy_2Led_efficacy_2Led_defaultLed_default Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4 ModerateModerateModerateModerate AlwaysAlwaysAlwaysAlways A littleA littleA littleA little
Dec 22, 2010 1.5 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_default Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4 Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_default NoneNoneNoneNone AlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at all
Mar 04, 2009   ? NoneNoneNoneNone AlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at all
Date
May 01, 2013
Advice & Tips
This was a very addictive treatment. Took it for years and finally decided to stop it after a slow taper from .5 to .25 and then .0. I had my SSRI increased and this has assisted with anxiety.
Cost
< $25 monthly
Date
Dec 22, 2010
Advice & Tips
I use this for MS symptoms. I have been on it a long time. I take it when I need it for anxiety during the day but it is primarily for night time.
Cost
< $25 monthly
Date
Mar 04, 2009
Advice & Tips
I take this medication to help me fall asleep, for clenching and muscle tightness. I sleep a lot better on it. I was prescribed it after a sleep study that showed I had alpha wave intrusions >=146 times per night because of pain.
Cost
< $25 monthly
  • Icon_thumb_off 0 helpful marks
Purpose: Epilepsy (Started Mar 29, 2013)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Apr 23, 2013 1 mg Daily ?Can't tell MildMildMildMildMild AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
Date
Apr 23, 2013
Advice & Tips
Decreased symptoms of anxiety/muscle tension/bruxism
Cost
< $25 monthly
  • Icon_thumb_off 0 helpful marks
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What is clonazepam?

Clonazepam is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Clonazepam affects chemicals in the brain that may become unbalanced and cause anxiety.

Clonazepam is used to treat seizure disorders or panic disorder.

Clonazepam may also be used for other purposes not listed in this medication guide.


Precautions

Do not use this medication if you have severe liver disease, or if you are allergic to clonazepam or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), lorazepam (Ativan), or oxazepam (Serax).

Before taking clonazepam, tell your doctor if you are allergic to any drugs, or if you have:

  • kidney or liver disease;
  • glaucoma;
  • asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;
  • a history of depression or suicidal thoughts or behavior; or
  • a history of drug or alcohol addiction.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category D. Clonazepam may cause harm to an unborn baby, and may cause breathing or feeding problems in a newborn. But having a seizure during pregnancy could harm both the mother and the baby. Do not start taking clonazepam during pregnancy without telling your doctor you are pregnant.

If you become pregnant while taking clonazepam for seizures, do not stop taking clonazepam without your doctor’s advice. Seizure control is very important during pregnancy and the benefits of preventing seizures may outweigh any risks posed by taking clonazepam.

Clonazepam may pass into breast milk and could harm a nursing baby. Do not breast-feed a baby while taking this medication.

The sedative effects of clonazepam may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking clonazepam.

Clonazepam may be habit-forming and should be used only by the person it was prescribed for. Clonazepam should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Do not drink alcohol while taking clonazepam. This medication can increase the effects of alcohol.

Clonazepam can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

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Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, and fainting.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

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Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • confusion, hallucinations, unusual thoughts or behavior;
  • hyperactivity, agitation, hostility;
  • unusual or involuntary eye movements;
  • weak or shallow breathing;
  • depressed mood, thoughts of suicide or hurting yourself;
  • chest tightness, fast or pounding heartbeats;
  • painful or difficult urination, urinating more or less than usual;
  • pale skin, easy bruising or bleeding; or
  • new or worsening seizures.

Less serious side effects may include:

  • drowsiness, dizziness, spinning sensation;
  • memory problems;
  • tired feeling, muscle weakness, lack of balance or coordination;
  • slurred speech;
  • drooling or dry mouth, sore gums;
  • runny or stuffy nose;
  • loss of appetite, nausea, diarrhea, constipation;
  • blurred vision;
  • headache;
  • nervousness, sleep problems (insomnia);
  • skin rash; or
  • weight changes.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for depression or anxiety can add to sleepiness caused by clonazepam. Tell your doctor if you regularly use any of these medicines, or any other seizure medications.

Also tell your doctor if you are using any of the following drugs:

  • propantheline (Pro-Banthine);
  • an antifungal medication such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend);
  • an antidepressant such as amitriptyline (Elavil, Etrafon), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), and others;
  • a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Luminal, Solfoton);
  • an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate); or
  • medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), mesoridazine (Serentil), pimozide (Orap), or thioridazine (Mellaril).

This list is not complete and there may be other drugs that can interact with clonazepam. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Other Names

Klonopin, Klonopin Wafer, and clonazepam

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Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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